Oral Presentations - Pathology and Laboratory Medicine - University ...

Graduate StudentV. Montoya 1 , J. Gardy 1,2 , K. Jewell 1 , S. Shah 1,3 , D. Huntsman 1,3 , P. Tang 1,21University of British Columbia, 2 BC Centre for Disease Control, 3 BC Cancer AgencyVincent MontoyaAbstract # 46microbial sequence characterization of ovarian cancertissueBackround/ObjectivesEpithelial ovarian cancer stands as the deadliest of all gynaecological malignancies. Among the heterogeneous subtypesof ovarian cancer, high-grade serous ovarian carcinomas (SOC) are clinically the most important. The known riskfactors associated with SOCs correlate with and include a history of upper genital tract infections collectively termedPelvic Inflammatory Disease (PID).MethodsWe sought to identify microbial sequences in SOC samples using 16S rRNA RT-PCR, a pan-viral microarray, andwhole transcriptome sequence analyses using next generation sequence data.Results and ConclusionsOur preliminary data provide evidence that SOC tissue is not as sterile as previously thought since bacteria, includingsome that are involved in PID and uterine tract infections, were recovered.Poster Presentations * 2 0 1 057