Table of Contentabstract #37 Expression of a multidrug-resistance protein (p-glycoprotein) gene (MDR-1) in the placenta of HIV infected<strong>and</strong> HAART-Exposed Women .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 48Eszter Papp, Deborah Money, Laura Oliveira, Tuhina Imam, Beheroze Sattha, Izabella Gadawski, Evelyn Maan,Jack Forbes, Hélène Côté38 Cardiolipotoxicity <strong>and</strong> hepatic dysfunction is augmented in Cbs +/- mice with diet-induced obesity .. . . . . . . . . . . . . . . . 49Melissa B Glier 1 , Dian C Sulistyoningrum 2 , Sanjoy Gosh 1 , <strong>and</strong> Angela M Devlin 1,239 Promoting pathology <strong>and</strong> laboratory medicine to medical students: The UBC <strong>Pathology</strong> <strong>and</strong> <strong>Laboratory</strong><strong>Medicine</strong> Student Interest Group (PaLM-SIG). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 50Serena Siow, Jacalynne Hern<strong>and</strong>ez-Lee40 Characterization of patients with very high plasma HDL-cholesterol, with <strong>and</strong> without vascular pathology .. . . . . . . . . . 51Ahmad Al-Sarraf MD 1, 2 , Gautamn Sarwal, BMLSc 2, 3 , Catalin Taraboanta, MD MSc 1 , <strong>and</strong> Jiri Frohlich, MD FRCP(C) 1,241 Deregulation of oncogene <strong>and</strong> tumor suppressor expression by methylation in early stage oral c .. . . . . . . . . . . . . . . . . . . 52Shevaun E. Hughes 1 , Ivy F.L. Tsui 1 , Catherine Poh 2,3 , <strong>and</strong> Cathie Garnis 1,242 Molecular characterization of anaplastic thyroid carcinomas .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 53Rebecca Towle 1 , Danielle MacNeil 1 , Ken Berean 2 , Don Anderson 1 , Cathie Garnis 143 Is the third AFB smear necessary to remove patients from respiratory isolation. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 54Am<strong>and</strong>a Wilmer 1,2 , Elizabeth Bryce 1,2 , Jennifer Grant 1,244 Skin aging as an indicator of cardiovascular health in apolipoprotein E knockout mice.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 55Paul R. Hiebert 1,2 , Thomas Abraham 1 , Sara Pazooki 1 , Wendy A. Boivin 1,2 , Hongyan Zhao 1 , David J. Granville 1,245 DNA quantity <strong>and</strong> quality from paraffin blocks: a comparison of fixation, processing <strong>and</strong> nucleic acidextraction techniques. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 56Gulisa Turashvili 1 , Melinda Carrier 1 , Nadia Gale 1 , Ying Ng 1 , Katie Chow1, Lynda Bell 1 , Margaret Luk 2 , Steve Kalloger 1 , Blake Gilks 2 ,Samuel Aparicio 1 , David Huntsman 146 Microbial sequence characterization of ovarian cancer tissue .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 57V. Montoya 1 , J. Gardy 1,2 , K. Jewell 1 , S. Shah 1,3 , D. Huntsman 1,3 , P. Tang 1,247 20(S)-protopanaxatriol affects the expression of cytochrome P450 3A4.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 58Nga Ting Colette Chiu 1 , Emma Tomlinson Guns 2 , William Jia 348 Death by boric acid - was Surekiller® a sure killer? .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59Walter Martz <strong>and</strong> Henry Kaliciak49 Combination of high performance liquid chromatography fluorescence detection <strong>and</strong> modern massspectrometry for analysis of primary amine derivatives in biological fluids <strong>and</strong> tissues .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 60Josephine H. Cheng 1 , Christine Joseph 1 , <strong>and</strong> Bernd O. Keller 150 Protein targets regulated by polyunsaturated fatty acid maternal diet in fetal rat brain.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 61Katelyn J. Janzen 1 , Elizabeth M. Novak 2 , Sheila M. Innis 2 , <strong>and</strong> Bernd O. Keller 151 Short antimicrobial peptides immobilized copolymer brushes on titanium surface. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 62Guangzheng Gao, Jason Kindrachuk, Donald E. Brooks, Robert E.W. Hancock, <strong>and</strong> Jayach<strong>and</strong>ran N. Kizhakkedathu52 Macromolecular iron chelators: a novel therapeutic agent for the treatment of secondary iron overload .. . . . . . . . . . . . 63Jasmine L. Hamilton, Muhammed Imran ul-haq, Iren Constantinescu, <strong>and</strong> Jayach<strong>and</strong>ran N. Kizhakkedathu53 Synthesis of biomimicking glycopolymer brushes containing different carbohydrate residues <strong>and</strong> theirnon-biofouling properties .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 64Kai Yu, Jayach<strong>and</strong>ran N Kizhakkedathu54 A novel lung tumor suppressor implicated in somatic <strong>and</strong> familial cancers.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 65Ian M. Wilson 1 , Katey S. S. Enfield 1 , Emily A. Vucic 1 , Raj Chari 1 , Yu-An Zhang 2 , Ming You 3 , Calum MacAulay 1 , Stephen Lam 1 ,Adi F. Gazdar 2 , Wan L. Lam 155 Amplification status of GAS41 <strong>and</strong> MDM2 in lung adenocarcinomas.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 66Larissa Pikor 1 , William W. Lockwood 2 , Raj Chari 1 , Emily A. Vucic 1 , Stephen Lam 1 , Adi F. Gazdar 3 <strong>and</strong> Wan L. Lam 156 Frequent DNA deletion of miRNA-101, a c<strong>and</strong>idate tumour suppressor, in lung cancer. .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 67Kelsie L. Thu 1,3 , Raj Chari 2,3 , Wan L. Lam 2,38
Table of Contentabstract #57 The role of eukaryotic translation initiation factor 2 alpha related pathways in autophagosome formationduring Coxsackievirus B3 induced myocarditis .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 68Tak Kwong Poon 1 , Jerry Wong 1 , John Zhang 1 , Guang Gao 1 , Honglin Luo 158 Avitene-induced necrotizing granulomatous inflammation developing post-craniotomy: a pediatric case series .. . . . 69Liat Apel-Sarid 1 , Doug Cochrane 2 , Paul Steinbok 2 , Angela Byrne 3 , Christopher Dunham 159 <strong>University</strong> of British Columbia microbiology curriculum Improvement report.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 70Kristel Lobo Prabhu 1 , Niamh Kelly 1 , Linda Hoang 1 , Muhammad Morshed 160 Using tissue microarrays to develop an immunohistochemical panel for basal-like breast cancer .. . . . . . . . . . . . . . . . . . . . 71Jennifer R. Choo 1,2 , Samuel Leung 2 , Dongxia Gao 2 , Christine Chow 2 , Sherman Y.H. Lau 2 , Jinjin Cheng 2 <strong>and</strong> Torsten O. Nielsen 1,261 Integrin-induced protein tyrosine phosphatase alpha (PTPa) tyrosine phosphorylation regulates cas-mediatedcell migration. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 72Suzanne Cheng 1,4 , Guobin Sun 2,4 , Catherine J. Pallen 1,2,3,462 Herpesviruses enhance generation of the clot-dissolving enzyme, plasmin, by tissue plasminogen activator:Correlation to virus-surface annexin II .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 73Edwin S. Gershom 1 , Michael R. Sutherl<strong>and</strong> 1, 2 <strong>and</strong> Edward L. G. Pryzdial 1, 263 Phenotypic <strong>and</strong> genomic variability of the 1q21.1 copy number variant (CNV) region in multigenerational families.. . 74*Harvard C. 1-3 , *Strong E. 1-3 , Martell S. 1-3 , Tyson C. 6 , McGillivray B. 4 , Hamilton S. 4 , Marles S. 7 , Mhanni A. 7 , Chow E. 10 ,Pavlidis P. 5 , Qiao Y. 1-4 , Holden J.J. A. 8,9 , Lewis M.E. S. 1,4 , <strong>and</strong> Rajcan-Separovic, E. 1-4 (*1st & 2nd author contributed equally to this work)64 Outcome of array CGH analysis for 255 subjects with intellectual disability (ID) <strong>and</strong> search for c<strong>and</strong>idategenes using bioinformatics .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 75Ying Qiao 1, 2 , Chansonette Harvard 1 , Christine Tyson 3 , Xudong Liu 4 , Celina Fawcett 3 , Paul Pavlidis 5 , Jeanette J.A. Holden 4 , SuzanneM.E. Lewis 2 , Evica Rajcan-Separovic 165 Effect of iron on antigen presenting cells: implications for transfusion dependent hemoglobinopathies. .. . . . . . . . . . . . 76Ibrahim Mustafa, Duncheng Wang <strong>and</strong> Mark D. Scott66 Mechanical properties of asthmatic airway smooth muscle revisited. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 77Leslie YM Chin 1,4 , Ynuk Bossé 4 , Dennis Solomon 4 , Tillie L Hackett 3,4 , Peter D. Paré 2,4 , <strong>and</strong> Chun Y. Seow 1,467 Y box binding protein-1 is a major contributor to sarcoma cells motility <strong>and</strong> aggressiveness. .. . . . . . . . . . . . . . . . . . . . . . . . 78Amal M. El-Naggar 1 ,2 , Cristina Tognon 2 , Fan Zhang 2 , Joan Mathers 2 , <strong>and</strong> Poul HB. Sorensen 1,268 The activation of the phosphatidyl-inositol-3 kinase pathway in response to the burkholderia cepaciacomplex infection .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79Billie Velapatiño 1 <strong>and</strong> David P Speert 269 Evaluation of two chromogenic media for screening of group b streptococcus in pregnant women .. . . . . . . . . . . . . . . . . 80Laura Book 1 , Ghada N. Al-Rawahi 1,2 , Eva Thomas 1,270 The role of brain high density lipoproteins in facilitating beta-amyloid degradation. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 81Sophie Stukas 1 , Sharon May 1 , Braydon Burgess 2 ,, Nicole DeValle 2 , Anna Wilkinson 1 , Veronica Hirsch-Reinshagen 1 ,M<strong>and</strong>ie Baker 2 , Michael N. Oda 2 <strong>and</strong> Cheryl L. Wellington 171 Coxsackievirus B3-induced downregulation of p58ipk is involved in shifting endoplasmic reticulumstress to cell apoptosis.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 82Mary Zhang, Xin Ye, Gomaa MH Hemida, Stefanie Mak <strong>and</strong> Decheng Yang72 Effect of polymer species <strong>and</strong> size on immunocamouflage <strong>and</strong> antigenicity .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 83Kyluik DL <strong>and</strong> Scott MD73 Regulation of cd1d expression in human b cells by retinoic acid receptor .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 84Lenka L. Allan, Annelein M. Stax, Dong-Jun Zheng, Brian K. Chung, Rusung Tan, <strong>and</strong> Peter van den Elzen74 T regulatory cell mediated protection of allograft in type 1 diabetes. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 85Joel Montane 1 , Loraine Bischoff 1 , Galina Soukhatcheva 1 , Lei Dai 1 , Gijs, Hardenberg 2 , Megan K. Levings 2 , Rusung Tan 1 , C. Bruce Verchere 1,275 Sulfatide-reactive T cells in multiple sclerosis .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 86Annelein Stax, Lenka Allan, Dong Jun Zheng, Peter van den Elzen9
- Page 2: PathDay: Keynote Speaker (4:30 pm)T
- Page 5: Conference Outline2010abstract #14
- Page 11 and 12: ResidentClinical SciencesArwa Al-Ri
- Page 13 and 14: ResidentTitus Wong 1 , Marc Romney,
- Page 17 and 18: ResidentD. Turbin 1 , D. Gao 2 , J.
- Page 19 and 20: ResidentDavid F Schaeffer 1 , Eric
- Page 21 and 22: ResidentMajid Zolein 1 , Daniel T.
- Page 23 and 24: Graduate StudentAshish K. Marwaha 1
- Page 25 and 26: Graduate StudentAmanda Vanden Hoek
- Page 27 and 28: Graduate StudentXin Ye 1 , Mary Zha
- Page 29: Graduate StudentLisa S. Ang 1 , Sar
- Page 32 and 33: Graduate StudentAbstract # 22Brian
- Page 36 and 37: OtherAbstract # 25Crystal Leung, Li
- Page 38 and 39: OtherAbstract # 27Lise Matzke 1 , W
- Page 40 and 41: Graduate StudentAbstract # 29Varun
- Page 42 and 43: Graduate StudentAbstract # 31Maite
- Page 44 and 45: Post-doctoral FellowAbstract # 33Ra
- Page 46 and 47: Graduate StudentAbstract # 35Hayley
- Page 48: Post-doctoral FellowAbstract # 37Es
- Page 51 and 52: ResidentAhmad Al-Sarraf MD 1, 2 , G
- Page 53 and 54: OtherRebecca Towle 1 , Danielle Mac
- Page 55 and 56: Graduate StudentPaul R. Hiebert 1,2
- Page 57 and 58:
Graduate StudentV. Montoya 1 , J. G
- Page 59 and 60:
OtherWalter Martz and Henry Kalicia
- Page 61 and 62:
OtherKatelyn J. Janzen 1 , Elizabet
- Page 63 and 64:
Graduate StudentJasmine L. Hamilton
- Page 65 and 66:
Graduate StudentIan M. Wilson 1 , K
- Page 67 and 68:
Graduate StudentKelsie L. Thu 1,3 ,
- Page 69 and 70:
OtherLiat Apel-Sarid 1 , Doug Cochr
- Page 71 and 72:
Graduate StudentJennifer R. Choo 1,
- Page 73 and 74:
Graduate StudentEdwin S. Gershom 1
- Page 75 and 76:
OtherYing Qiao 1, 2 , Chansonette H
- Page 77 and 78:
Graduate StudentLeslie YM Chin 1,4
- Page 79 and 80:
Graduate StudentBillie Velapatiño
- Page 81 and 82:
Graduate StudentSophie Stukas 1 , S
- Page 83 and 84:
Graduate StudentKyluik DL and Scott
- Page 85 and 86:
Post-doctoral FellowJoel Montane 1
- Page 87 and 88:
IndexAAbozina A. 45Abraham T. 55All
- Page 89:
Ye X. 27, 82Yee S. 31Yoshida E. 12Y