Diagnosis and Management of Pituitary Tumors

CHAPTER 16 / PROLACTINOMAS 285term of up to 8 yr (84–87). Most microprolactinomas remain stablein size; 25 yr). Lisuride (92,93) has also beenused extensively over the years. The other newer compounds haveonly been recently introduced into the therapeutic armamentariumoutside the US.BROMOCRIPTINE At present, oral bromocriptine is consideredthe “gold standard” of DA agonist therapy (5,32,88,91,94).About 25–30% of the drug is absorbed. It is rapidly and effectivelyremoved by the liver and undergoes hepatic degradation into biologicallyinactive metabolites. Only