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Balloon Valvuloplasty for Critical Neonatal Aortic Stenosis: InitialResults and Long Term Follow-upO. H. EL Shazali, J. J. O'Sullivan, D. S. CrosslandPaediatric Cardiology, Freeman Hospital, Newcastle upon Tyne, UKThe purpose of this study is to assess the safety and effectiveness of aortic valve ballooningfor critical neonatal aortic stenosis and to look at intermediate and long termfollow up.The study is a retrospective review of notes, echocardiograms and haemodynamic dataof all babies (less than 3 months of age), treated at our institution between August 1985and December 2002.28 babies underwent balloon valvuloplasty for critical aortic stenosis, mean age was 25days (range 1-89), mean weight was 3.3 Kg (range 2.1 - 5.6), mean follow up periodwas 6.3 years (range 0.5 - 16 years).There were 7 deaths (25%), all of them occurred within 4 weeks post ballooning, 3of them had severe heart failure and were ventilated and on inotropic support withevidence of multi-organ failure pre-ballooning. There was no death within the last 5years.8 babies developed significant aortic regurgitation and 12 babies had significant residualaortic stenosis and 2 of them needed re-ballooning, one at 1 year of age and thesecond one at 2 years of age.4 patients underwent Ross procedure at 4,9, 10, 10 years of age.Conclusion: Ballooning of neonatal critical aortic stenosis is associated with significantmortality and morbidity especially in very sick neonates, patients should haveregular and long term follow up.Audit of Management of Sickle Cell CrisesIn Children in a London HospitalDr. Abdelmoniem Mohamed Hamid, MBBS, MRCPCH.Consultant Paediatrician, Kettering General Hospital, Kettering, UKAfrica is the birthplace of sickle cell disease with millions with sickle cell trait, andnewboms affected by sickle cell disease (SCD) are estimated at 200,000 per year.The disease is also prevalent in variable degrees in other parts of the world includingUK, USA, the Caribbean, the Mediterranean, Saudi Arabia and India. There are about10000 in UK. Whereas management of children with SCD in the developed world iswell structured and organised by protocols and close follow up, it is lacking behind inAfrica.