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Dengue HaemorrhagicFever in Port Sudan LocalityDr. Amel Aziz Malik, MD. (Paediatrics)Head Dept. of Paediatrics, Faculty of Medicine, University of Red SeaDengue is the most important emerging tropical viral disease of humans in the worldtoday. It is a mosquito born disease transmitted by Aedes aegypti. WHO(l999) estimatedthat there are 2.5 billions of population worldwide are at risk of contracting thedengue fever where 50 to 100 million cases of dengue fever(DF)and about500,000cases of dengue hemorrhagic fever (DHF) each year which require hospitalization.Since 1967 DF has been reported in Sudan (WHO 1997), DF type 2(not DHF) wasdiagnosed virologically in Port Sudan locality in 1986 and 2003. Objectives: To studythe pattern of emerging DHF in Port Sudan.This study was conducted in Port Sudan Paediatric Hospital and SPC Hospital in theperiod 111112004 - 30/6/2005. Most of the cases of suspected DHF according to WHOcriteria (Excluding tourniquet test) were included in this study.Data were collected from 307 cases of suspected DHF 188(61.2%) male and 119(38.8%)female between the ageS-month to IS years. [Mean age 7.5 years old].Clinically all cases in our sample presented with fever [100%] of 4-7 days duration,(68%) presented with easy bruising and bleeding at vein puncture site and/or petechiaein skin, mucous membrane and bleeding from other sites,(33.2%)with epistaxis,(36.5%) with haematemesis and (27%) malena. Dengue shock syndrome (DSS) wasdiagnosed in 32 cases (9.1 %).The mortality rate was (2.2%).Platelets count was done in 280 pt thrombocytopenia (platelets 100,000 cells/cu mmor less)found in (69.5%) of them, u/s abdomen was done to 36 cases and 16 patienthave pleural effusion and/or ascites .Sample for serological test were collected from82 cases and 35 samples were discarded due to haemolysis. Dengue IgM antibodieswere detected in 37 cases, 10 undetected (possibly due to inappropriate time of samplecollection).Preventive measures should include community participation, environmental managementof the vector control tools, education of health personnel and improvement oflaboratory facilities.