Chapter 133
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Implications for Humanitarian<br />
Anesthesia<br />
George A. Gregory<br />
<strong>133</strong><br />
CHAPTER<br />
Many people in developing countries live their whole lives without<br />
having congenital anomalies repaired. Patients with congenital<br />
heart lesions, for instance, may die for lack of a surgeon, anesthesiologist,<br />
equipment, hospital, or operating room. Some die<br />
because they lack funds to pay for the surgery. Organizations in<br />
many developed countries provide free plastic, orthopedic, cardiac,<br />
or ophthalmologic surgery for poor people in developing countries.<br />
These programs, in one form or another, have existed for ore than<br />
100 years: missionaries went to Africa and Hawaii in the 18th and<br />
19th centuries and established hospitals to care for needy patients.<br />
In the mid-20th century, Orbis and the ship Hope began providing<br />
care in developing countries for patients with ophthalmologic and<br />
other problems. In 1969, Interplast (Mountain View, CA) began<br />
providing free reconstructive surgery for needy patients who had<br />
cleft lips, cleft palates, and burns. 1 Now more than 100 organizations<br />
throughout the world provide similar care. Unfortunately, there is<br />
no regulation of organizations providing care, and mortality rates<br />
are higher than those in developed countries for the same surgery. 2<br />
The purpose of this chapter is to discuss the environment in which<br />
these surgical trips take place and to describe ways that needed care<br />
can be provided in austere environments.<br />
There are many ways for organizations to deliver care for these<br />
patients. Some organizations consist of a few people that work<br />
together all of the time. Others consist of large groups of people<br />
who seldom or never have worked together. This chapter is written<br />
from the point of view of a larger organization that provides care<br />
for poor people in developing countries, but the principles<br />
discussed can be applied to small as well as large groups.<br />
GOALS<br />
The primary goal of most medical nonprofit organizations working<br />
overseas is to provide free, safe, effective care for poor patients.<br />
These groups seek to provide a level of care commensurate with<br />
that provided at home. A second goal is to educate local physicians<br />
and nurses and to provide them with the resources that will allow<br />
them to deliver needed care themselves.<br />
Needy patients receive care from overseas groups in one of<br />
several ways. First, a group of physicians and nurses from a<br />
developed country goes to a less-developed country and provides<br />
direct care to patients (e.g., surgery). They treat a number<br />
of patients during each short trip, but many patients remain<br />
untreated. A second and more effective way to provide care is to<br />
give local surgeons, anesthesiologists, and nurses the education,<br />
equipment, and materials they need to do the surgery themselves.<br />
ORGANIZATION<br />
Organizations that provide free care for poor patients in developing<br />
countries are generally not-for-profit, although there is no<br />
reason they have to be. Funding for these organizations usually<br />
comes from private industry and from individuals. Larger organizations<br />
have a board of directors that oversees the running of the<br />
organization and aids in fund raising. The board of directors<br />
provides guidance to a chief executive officer (CEO). The CEO is<br />
responsible for the day-to-day running of the organization and for<br />
fund raising. A chief medical officer (CMO) provides medical<br />
leadership and visits possible new surgical sites and deals with<br />
local governments and physicians. The CMO is the liaison between<br />
the medical personnel and the organization’s administration.<br />
Larger groups have surgical, anesthesia, pediatric, and translator<br />
committees that may meet several times a year to set policy for<br />
each group. Many organizations have a steering committee that is<br />
made up of members of each of these groups and is responsible<br />
for setting policy for trips and for sending these policies to the<br />
CMO, CEO, and board of directors for action. One of the most<br />
important components of these organizations is the supply department,<br />
which organizes donated and purchased supplies for trips<br />
and sends them at the appropriate time to the appropriate location<br />
so teams can do their work.<br />
Surgical teams are made up of volunteers who may not have<br />
worked together and must now work as a team in less-than-ideal<br />
conditions. Teams include a team leader, anesthesiologists/nurse<br />
anesthetists, surgeons, operating room and recovery room nurses,<br />
a pediatrician/general practitioner who is responsible for pre- and<br />
postoperative care of the patients and the health of the team, and<br />
translators. Some teams include physical therapists, dentists, dental<br />
technicians, and/or speech therapists.<br />
Team members must adapt easily to change and must be able<br />
be to get along with each other in difficult and often fatiguing<br />
situations. Egos must be left at home. The extreme poverty of some<br />
sites is especially difficult for some team members. The anesthesia<br />
providers, nurses, surgeons, and translators usually have leaders<br />
who are responsible to the team leader. The team leader is in<br />
charge of the entire trip and deals with local physicians, hospital<br />
authorities, and others. The role of each team member must be<br />
made clear at the outset and people should stay within those roles.<br />
It is a good idea to have team members meet via a telephone<br />
call several weeks before the departure time. This phone call allows<br />
people to introduce themselves to each other and for the organization’s<br />
administration to make themselves known to the team.<br />
Questions can be answered, and the team can be told the kind and
2174 PART 6 ■ Specific Considerations<br />
quantity of surgeries to expect. The administration can make clear<br />
the goals of the trip and the rules of team conduct.<br />
Sexual harassment, either physical or verbal, is not to be<br />
tolerated and may result in a team member being sent home for<br />
engaging in these activities. Romantic liaisons with a team member<br />
or a local person may threaten the present trip and future trips<br />
to that site. Logistic details such as living arrangements, costs to<br />
the team (meals and other expenses) should be made clear. Team<br />
members should be told approximately how much money they<br />
will require for expenses. One member of the team should be<br />
designated as the “team physician”; the most appropriate person<br />
for this role is the pediatrician/general practitioner, if there is one<br />
as part of the team. This person should be made aware of health<br />
problems of team members (e.g., diabetes, asthma) before the trip<br />
begins (not during the phone call, for reasons of confidentiality).<br />
If infectious diseases such as avian flu are prevalent at the trip site,<br />
the team should be told how sick team members will be treated<br />
medically and how they will be evacuated home. Team members<br />
who have previously been to the site can address local customs<br />
and dress code. Drugs, tobacco, and alcohol use can be discussed<br />
and the rules made clear by the organization’s leaders. Giving<br />
individual gifts or money to patients or their families often causes<br />
problems, because one group may perceive that they received a<br />
lesser gift than another. The organization can indicate during the<br />
phone call that the organization will give the same gift to each<br />
patient/family and avoid these problems. Often the hosts at a site<br />
give small gifts to team members. It is difficult to refuse these gifts<br />
without seeming rude.<br />
TEAM LEADERSHIP<br />
Each trip should have a team leader who is responsible for the dayto-day<br />
running of the trip and for solving problems. Each specialty<br />
group (anesthesiologists, surgeons, nurses, etc) should have a<br />
leader who deals with the day-to-day details of the trip related to<br />
their specialty. Trips function better when there are frequent<br />
discussions between the leaders and the team members. Having<br />
team meetings at breakfast or dinner, when everyone is together,<br />
is one way to accomplish this. Cases for the day or any problems<br />
that occurred with the surgery schedule can be discussed. Before<br />
the first surgery takes place, it is helpful to have a team meeting<br />
to orient team members to the site and let them know where the<br />
fire extinguisher, emergency oxygen tanks, emergency drugs, defibrillator,<br />
and so on are located. During this meeting, team<br />
members can be told how to contact the pediatrician/general<br />
practitioner during the day and how emergencies will be handled,<br />
especially if a patient must return to surgery for any reason. If a<br />
patient requires intensive care, some organizations put the patient<br />
in the hospital’s intensive care unit (ICU) and others have an<br />
anesthesiologist and a postanesthesia care unit (PACU) nurse care<br />
for the patient in the PACU. If an anesthesiologist and nurse are up<br />
all night caring for a patient, they may be tired and not function<br />
well the following day. This may necessitate canceling some<br />
surgery. Canceling cases may be difficult, but if it is safer for<br />
patients it must be done. A surgeon, anesthesiologist, nurse, and<br />
translator should make rounds after dinner and see all patients<br />
operated upon that day to determine whether there are any<br />
problems and if the patients have adequate pain relief. The same<br />
group can take night call that night. The hospital must be able to<br />
contact the team leader at all times, including night and weekends.<br />
CHOOSING AND EVALUATING SITES<br />
Although different organizations use different models for site<br />
selection, it is generally considered best if organizations are invited<br />
to provide surgery in a country by physicians, governments (local<br />
or federal), or service groups (Rotary clubs, Lions clubs, etc). If<br />
local medical professionals are not involved in the invitation, they<br />
may feel the trip was forced on them and refuse to work or<br />
cooperate with the team. Government officials also must be aware<br />
of the invitation. Without the government’s cooperation, the team<br />
may be denied entrance to the country and may be prevented from<br />
doing surgery. After all, it is the government that allows team<br />
members to practice medicine in their country without a license.<br />
Most countries allow us to practice medicine, nursing, and so on<br />
in-country without having a license to do so, for the time we are<br />
there. Malpractice insurance is seldom available for this type of<br />
work. To date, there have been no lawsuits for such care. Host<br />
physicians are responsible for all interactions with the team and<br />
the parent organization. The host must be able to communicate<br />
with the organization’s offices by e-mail or by telephone.<br />
When an organization considers performing surgery in a<br />
country, a letter asking certain questions should be sent to whoever<br />
it was that proffered the invitation, such as questions regarding the<br />
stability of the government and whether bribes are expected to<br />
permit teams to work in the country are important. It is illegal for<br />
Americans to take or give bribes in this situation, according to the<br />
Foreign Corrupt Practices Act (http://www.justice.gov/criminal/<br />
fraud/fcpa). Whether it is safe for foreigners to be in the country<br />
must be addressed.<br />
Are there sufficient patients who require the type of surgery<br />
that can be provided? If there are, how will they be recruited? Will<br />
newspaper, television, and radio advertisements be used? Who<br />
will place the advertisements, when will they be placed, and who<br />
will pay for them? Are similar surgical groups working in the area<br />
and when were they last there? If other teams have been in the area<br />
recently or recruiting was inadequate, insufficient patients may be<br />
available to make the trip cost-effective or satisfying for the team<br />
members.<br />
The parent organization and CMO must make clear to the host<br />
what type of surgery the team can and will do. Orthopedic<br />
surgeons will not repair cleft lips and plastic surgeons will not do<br />
pelvic osteotomies. It is then up to the host physician(s) to find<br />
appropriate candidates for surgery. The host(s) must be willing<br />
and able to provide needed follow-up care for the patients after<br />
the team leaves. Ideally, this person should be a surgeon who will<br />
be the focus of teaching during a trip and who has the potential to<br />
lead her/his own team and provide the same type of surgery for<br />
poor patients in the future. For burn patients in particular, the<br />
personnel and the facilities must be available for postoperative<br />
care, including splinting and physical therapy if required.<br />
Who will help with customs, transport of the team and<br />
equipment from the airport to the hotel, and from the hotel to the<br />
hospital? Will someone be available every day to help solve<br />
problems? If the team’s equipment is confiscated or delayed by<br />
customs, as it sometimes is, how will this problem be resolved? Is<br />
there a locked, safe room in which to store equipment and drugs?<br />
Who will have access to this area at night? How will the team<br />
access this room at night if they must provide emergency surgery?<br />
Is the operating environment adequate? Are there sufficient<br />
rooms in which to perform surgery without compromising patient<br />
safety or the ability of local surgeons to care for their patients?<br />
How many operating rooms will be available to the team? Placing
CHAPTER <strong>133</strong> ■ Implications for Humanitarian Anesthesia 2175<br />
two operating tables in one room and having two teams operate at<br />
the same time, as is done daily in many developing countries, is<br />
usually safer because anesthesiologists can share equipment when<br />
necessary and can help one another if a problem arises. Surgeons<br />
can easily consult with each other about the surgery. Teaching is<br />
improved because local surgeons and anesthesia personnel can be<br />
shown interesting findings and techniques. At times the operating<br />
rooms can be very crowded and noisy. (If they are, as your mother<br />
said, “patience is a virtue.”)<br />
Is safe, well-maintained anesthesia equipment available?<br />
Anesthesia vaporizers may not have been serviced for years, if<br />
ever, making it impossible to know what concentration of anesthetic<br />
is being delivered. Is oxygen available? If so does it come<br />
from the wall, from tanks, or from concentrators? Are replacement<br />
oxygen tanks available on-site? Can empty oxygen tanks be<br />
replaced quickly? Can they be accessed rapidly 24 hours a day?<br />
Are the hose fittings on the reducing valves the same as those on<br />
the hoses and regulators brought by the team? If not, how can this<br />
problem be solved? One possible solution is to rent appropriate<br />
equipment from firms in the country where the work will be done.<br />
This is rarely possible; when it is, the rental costs may be excessive.<br />
Is oxygen available for transport of the patient from the<br />
operating room to the PACU? The distance between these two<br />
areas can be great enough that oxygen desaturation will occur by<br />
the time the patients arrives in the PACU if added oxygen is not<br />
used during transport. This is especially true when surgery is<br />
performed at altitude (Table <strong>133</strong>–1).<br />
The 20 patients described in Table <strong>133</strong>–1 were studied at greater<br />
than 10,000 feet (3,048 meters) above sea level. They breathed<br />
100% oxygen for 5 minutes in the operating room before being<br />
quickly taken to the PACU, which was about 50 yards (46 meters)<br />
away. No oxygen was available for transport. Ten of the patients<br />
were hyperventilated to an end-tidal PaCO 2<br />
of 20 to 25 mmHg<br />
before leaving the operating room to cause apnea. They remained<br />
apneic during transport and their SaO 2<br />
was acceptable upon arrival<br />
in the PACU. Patients who were not hyperventilated breathed<br />
spontaneously during transport and had lower initial SaO 2<br />
s on<br />
arriving at the PACU.<br />
Are gurneys or stretchers available for transport of patients to<br />
the PACU, or does someone have to carry the patient? Carrying<br />
larger patients is a problem. Is oxygen available in the PACU? Does<br />
it come from the wall or from tanks? How many oxygen outlets are<br />
there? Will one or more patients have to share the same oxygen<br />
source? Is suction available from the wall or from a suction<br />
machine? Is suction available for each patient? Are monitors<br />
available? Can heart rate, noninvasive arterial blood pressure,<br />
electrocardiogram (ECG), and SpO 2<br />
be monitored? If not, the<br />
team must provide appropriate monitors for use in the PACU.<br />
Although there are many ways to do things, organizations<br />
usually do not charge patients for services they receive from<br />
visiting teams. During the site visit, hospital administrators and<br />
TABLE <strong>133</strong>-1. Oxygen Saturation Upon Arrival in the<br />
Postanesthesia Care Unit (PACU)<br />
SaO 2<br />
in PACU<br />
Without<br />
SaO 2<br />
in PACU With<br />
SaO 2<br />
in Operating Hyperventilation, Hyperventilation,<br />
Room, % (No.) % (No.) % (No.)<br />
100 (20) 86 ± 8 (10) 95 ± 6 (10)<br />
others should be made aware that this is the policy of the organization.<br />
Some hospitals have been known to extract fees from<br />
patients for care provided by visiting teams.<br />
Discrimination against anyone on the basis of color, race, or<br />
religion is strictly prohibited. Nonprovision of care is based solely<br />
for medical reasons or the inability of the team to perform the<br />
required surgery. Competent translators are required throughout<br />
the trip, both for patient care and for teaching.<br />
Is the hotel clean and free of “varmints”? Does the hotel have<br />
hot water and electricity? Is it safe to leave personal belongings<br />
such as cameras, laptops, and other equipment in the hotel? Will<br />
it be safe to leave these items around the operating and recovery<br />
rooms? The cost of this equipment is more than the income<br />
received by many doctors over several years. How will lunch be<br />
provided and who will provide it? What will the cost be? Will the<br />
organization pay for lunch? Is there malaria, dengue fever, bird<br />
flu, HIV, and so on in the area? Plans for acute and long-term care<br />
of infected team members should be clearly defined. AIDS is<br />
endemic in some developing countries. This increases the risk to<br />
team members who are accidently stuck with needles from<br />
infected patients. A rapid HIV test kit should accompany each<br />
team so the team physician can quickly determine if the person<br />
from whom the blood originated is HIV-positive. If the patient is<br />
HIV-positive and the team member is HIV-negative, there is a 4-<br />
hour window from the time the needle stick occurs to treatment<br />
with appropriate drugs to reduce her/his likelihood of becoming<br />
infected. By taking drugs such as combivir with them, the team<br />
physician can treat potentially infected team members quickly and<br />
plan for their evacuation home. It is better not to count on<br />
obtaining these drugs within the country where the team is<br />
working. It may not be possible to acquire them in the requisite 4<br />
hours.<br />
CHOOSING PATIENTS FOR SURGERY<br />
Candidates for surgery should be healthy and have an American<br />
Society of Anesthesiologists (ASA) physical status 1 or 2. Whether<br />
children with congenital anomalies (other than those for which<br />
they are receiving surgery) are appropriate candidates for surgery<br />
by these groups should be determined on a case-by-case basis.<br />
Patients with clefts, orthopedic anomalies, and ophthalmologic<br />
anomalies are usually appropriate candidates, assuming they have<br />
no other serious anomalies and the blood loss will be small.<br />
Patients with congenital heart disease other than those scheduled<br />
for cardiac surgery or patients with significant lung disease (e.g.,<br />
severe asthma) are seldom appropriate candidates for surgery by<br />
visiting groups. Patients with syndromes that include cardiac,<br />
respiratory, renal, hepatic, or facial anomalies that make it difficult<br />
to ventilate the patient’s lungs with a bag and mask are not<br />
candidates for surgery, because their perioperative complication<br />
rates may be excessive. If a team cannot operate on the patient,<br />
attempts should be made to find surgery for the patient within the<br />
country or in another country. Patients with chronic undernutrition<br />
are seldom candidates for surgery because they heal poorly. If<br />
the team can help improve the patient’s nutritional state by helping<br />
the family purchase food, it may be possible for the patient to have<br />
surgery at a later date.<br />
WORK ENVIRONMENT<br />
The environment in which visiting teams and local physicians and<br />
nurses must work can often be difficult. Hospitals range from
2176 PART 6 ■ Specific Considerations<br />
makeshift buildings in a jungle that are used rarely, or only when<br />
teams from developed countries go there to perform surgery, to<br />
hospitals that are quite modern but may only be open when<br />
visiting teams are there because the government lacks sufficient<br />
funds to staff and furnish the hospital. In between are many<br />
hospitals with multiple problems. Electricity is available in most<br />
hospitals, although it may cut off several times a day. When it does<br />
the team has to rely on backup systems. The site visitor must<br />
determine if there is a backup electrical generator and if it actually<br />
works. Battery-operated headlights and bright, focused flashlights<br />
will usually suffice until the electricity is restored. The water<br />
supply may be unclean and may cut off several times a day. Many<br />
sites are warm and humid. Others are cold, especially those located<br />
in high mountains (e.g., the Andes or Himalayas). Teams going to<br />
high-altitude sites should be prepared to deal with high-altitude<br />
pulmonary and/or cerebral edema in team members. 3 Because<br />
most team members live near sea level, sudden changes in altitude<br />
may induce one or both of these problems if the person is<br />
susceptible.<br />
ORGANIZATION OF THE TRIP<br />
Screening<br />
Many teams hold a clinic the day after they arrive at a site to<br />
determine who will receive surgery. More than 200 people may<br />
show for evaluation; not all will be appropriate surgical candidates.<br />
Many appropriate candidates will be denied surgery because there<br />
is no room on the surgery schedule for them; they can be told to<br />
return the following year. All patients must be seen and examined<br />
by the surgeons to determine if it is possible to do the required<br />
surgery. The pediatrician/general practitioner must clear the<br />
patients medically for surgery; the anesthesiologist must determine<br />
the risk of anesthesia and potential intra- or postoperative<br />
problems. These evaluations overlap, which usually prevents<br />
inappropriate surgery from taking place. Acute or chronic illnesses<br />
commonly prevent surgery from taking place. Children with an<br />
upper respiratory tract infection (URI) are not candidates for<br />
surgery during a trip, because the potential risk for airway<br />
problems is too high. 4 Patients who have an URI should not be<br />
treated with antibiotics and told to return for surgery the following<br />
week. Even if they do not have problems during surgery, many<br />
patients who have an URI may have respiratory and airway<br />
problems in the PACU. 5 Whether to proceed with surgery is a joint<br />
decision by all physicians who saw the patient. It may be possible<br />
to accomplish surgery safely, but it may not be possible to provide<br />
the level of postoperative care required. If this is the case, the<br />
surgery should not take place.<br />
There is often pressure from the team, from local physicians,<br />
and from hospital administrators to operate on patients because<br />
the patient came from far away. This may be her/his only chance<br />
to have surgery. However, if there are good medical reasons to<br />
delay or to not perform surgery, it should not be done.<br />
Patients usually arrive at the hospital the day before surgery.<br />
The pediatrician/generalist evaluates them and determines if they<br />
have had an intercurrent infection or other problem after the clinic<br />
visit. Information provided during the clinic visit must be<br />
confirmed. Patients or their families may hide or alter information<br />
(such as regarding fasting) if they think disclosing that information<br />
will prevent surgery from occurring. A thorough physical<br />
examination and further questioning about heart, lung, renal,<br />
central nervous system, and hepatic disease is required. Many<br />
patients in developing countries have asthma that has never been<br />
diagnosed or treated. A careful asthma history and examination<br />
are mandatory. If a patient is found to have bronchospasm, the<br />
surgery may have to be delayed while appropriate therapy is<br />
begun. It is not uncommon to find patients who have significant<br />
asthma and have never been treated for this problem. Laboratory<br />
work is done and blood for transfusion is ordered if needed. If a<br />
blood transfusion is needed, a family member may have to donate<br />
blood for the patient. Most organizations pay the costs of blood<br />
banking and laboratory tests.<br />
The patient/parents are informed during the clinic visit and<br />
during preoperative rounds the night before surgery when they or<br />
their child must be made NPO. NPO times are the same as those<br />
of the ASA: 6 hours for milk, formula, or solids; 4 hours for breast<br />
milk; and 2 hours for clear liquids. Clear liquids are fluids the<br />
patient/parents can see through (water, apple juice). Many people<br />
in developing countries believe that patients require a hearty<br />
breakfast before surgery to assure a good outcome. If they fear that<br />
the surgery will be canceled if the patient drank or ate, they may<br />
not tell the anesthesiologist that they or their child is not NPO.<br />
Families must understand the reason for NPO and the dangers of<br />
eating or drinking before surgery. On the morning of surgery the<br />
anesthesiologist should again question the patient/parents about<br />
the NPO status. You might find they ate steak and eggs an hour<br />
ago. Asking “What did you have for breakfast?” is usually more<br />
effective than asking “Did you eat or drink anything this morning?”<br />
The former often catches them off guard and they disclose<br />
what they ate or drank.<br />
Young children can be premedicated with a mixture of<br />
midazolam and 30 to 50 mL of cola, depending on the patient’s age. 6<br />
Place 0.5 to 1.0 mg/kg of midazolam in a small cup and show them<br />
the cola container; pour cola into the cup and hand the cup to the<br />
parents to give to the child. Children will almost always drinks the<br />
mixture quickly. After 15 to 20 minutes, the child will be relaxed<br />
and can be taken to the operating room for the induction of<br />
anesthesia. Adding 2 to 3 mg/kg of ketamine and 0.5 mg/kg of<br />
midazolam to a cup, along with cola, and having the child drink the<br />
solution usually produces a sleeping child in 15 to 20 minutes. Half<br />
of the oral ketamine and midazolam are metabolized by the firstpass<br />
effect. 7 Naturally, the children are afraid of strangers and do<br />
not want to leave their parents. Premedication overcomes the<br />
reluctance of many of these patients. It also facilitates the induction<br />
of anesthesia, especially if the anesthesiologist does not speak<br />
the local language. Local physicians seldom premedicate infants and<br />
children. If we teach them to do so, we must also teach them the<br />
potential problems and the postoperative care of premedicated<br />
patients.<br />
Mixing 0.9 ml of lidocaine (1%) and 0.1 ml of sodium bicarbonate<br />
in a 1-mL syringe and using a 30 or 32-gauge needle to<br />
inject 0.2 to 0.5 mL of the solution into the skin prevents the pain<br />
of injection and of catheter insertion. When the I.V. is in place,<br />
0.05 to 0.2 mg/kg of midazolam can be given intravenously. Rectal<br />
premedication is not used in some countries due to cultural taboos.<br />
Equipment<br />
Most groups take all surgical supplies and instruments, monitors,<br />
drugs, and anesthetics required with them to the site. Narcotics<br />
and other schedule II to IV drugs should not be taken into the<br />
country unless one wishes to become familiar with the inside of
CHAPTER <strong>133</strong> ■ Implications for Humanitarian Anesthesia 2177<br />
the local jail. Fentanyl is readily available in most countries. Table<br />
<strong>133</strong>–2 is a list of the drugs commonly taken on trips. Many of these<br />
drugs can be purchased in the country where the team will work.<br />
However, one should be aware that drug names are often different,<br />
and language barriers can further increase the risk of making a<br />
drug error. The dosage of drugs from local companies may be<br />
different from the dosage of drugs usually used by team members,<br />
which increases the risk of administering an incorrect dose of drug<br />
during an emergency. It is best to check the dose to be given with<br />
a colleague before administering the drug. Drugs drawn into<br />
TABLE <strong>133</strong>-2. Drugs Commonly Provided by Teams on Medical Trips<br />
Vagolytics, Vasopressors<br />
Atropine sulfate, injectable, 0.4 mg/mL, 1-mL vial<br />
Ephedrine sulfate, injectable, 50 mg/mL, 1-mL vial<br />
Epinephrine, injectable, 1:1000 (1 mg/mL), 1-mL ampule<br />
Glycopyrrolate, injectable, 0.2 mg/mL, 1-mL vial<br />
Neuromuscular Blockers, Reversal Agents<br />
Succinylcholine chloride, injectable, (Quelicin), 200 mg<br />
(20 mg/mL)<br />
Rocuronium (Zemuron), 0.45–0.65 mg/kg for tracheal intubation;<br />
0.05–0.2 mg/kg if reparalysis is required, 50-mg vial<br />
Vecuronium (Norcuron), 0.08–0.1 mg/kg, 10-mg vial<br />
Neostigmine methylsulfate, 0.5 mg/mL, 1:2000, 10-mL vial<br />
Analgesics and Sedatives<br />
Ketamine HCL (Ketalar), injectable, 100 mg/mL, 5-mL vial<br />
Nalbuphine (Nubain), injectable, 10 mg/mL, 1 mL ampule<br />
Naloxone HCL (Narcan) injectable, 0.4 mg/mL, 1 mL ampule<br />
Butorphanol tartrate, injectable (Stadol), 0.5–2 mg, 2 mg/mL,<br />
1 mL vial<br />
Tramadol (Ultram), 2 mg/kg up to 100 mg/dose; maximum<br />
dose 300 mg/day, 100-mg tablets<br />
Anti-Emetics, Steroids, and Antihistamines<br />
Diphenhydramine HCL (Benadryl), injectable, 50 mg/mL<br />
Droperidol, injectable, 2.5 mg/mL<br />
Metoclopramide HCL injectable, 10 mg/mL<br />
Major Anesthetic Agents<br />
Sevoflurane (Ultane), 250-mL bottle<br />
Isoflurane (Forane), 250-mL bottle<br />
Propofol 1% (10 mg/mL), 20-mL vial<br />
Local Anesthetics (Not for Spinal or Epidural)<br />
Bupivicaine HCL 0.5%, injectable (Sensorcaine), 50-mL vial<br />
Lidocaine HCL 2%, injectable (Xylocaine), 50-mL vial<br />
Lidocaine 1% plain, 50-mL bottle<br />
Lidocaine 1% with epinephrine, 50-mL bottle<br />
Antibiotics<br />
Cefazolin, 1 gm, 1-gm vial<br />
Sterile water for injection, 50-mL vial<br />
Antibiotic ointment (1-oz tube)<br />
Cephalexin, 250-mg capsules (500/bottle)<br />
Cephalexin, 500-mg capsules (100/bottle)<br />
Bacitracin ointment, 32-oz packets<br />
Other Drugs<br />
Adenosine injectable, 6 mg (3 mg/mL) (Adenocard), 2-mL vial<br />
Albuterol USP, inhaler<br />
Atropine sulfate, injectable, 0.5 mg (0.1 mg/mL) 5-mL-PFS<br />
Calcium gluconate 10% (0.465 mg/mL), 10-mL vial<br />
Dexamethasone phosphate, injectable, 4 mg/mL (Decadron),<br />
5-mL vial<br />
Dextrose injectable, 50% in water, 25 g (0.5 g/mL), 50-mL vial<br />
Dopamine HCL injectable, 200 mg (40 mg/mL), 5-mL vial<br />
Epinephrine injectable, 1:10000, 1 mg (0.1 mg/mL), 10-mLprefilled<br />
syringe<br />
Furosemide injectable (Lasix), 20 mg/mL 2-mL vial<br />
Hydralazine HCL, 20 mg/mL, 1-mL vial<br />
Labetalol hydrochloride injection, USP (5 mg/mL), 20-mL vial<br />
Lidocaine HCL, 2% (Xylocaine), 100 mg (20 mg/mL),<br />
5-mL-PFS<br />
Metoprolol tartrate, 1 mg/mL, 5-mL ampule<br />
Phenylephrine HCL, injectable, 1% (10 mg/mL)<br />
(Neosynephrine), 1-mL vial<br />
Sodium bicarbonate, injectable, 4.2% (Infant), 10-mL-PFS<br />
Sodium bicarbonate, injectable, 8.4%, 50 mEq (1mEq/mL),<br />
50-mL vial<br />
Verapamil HCL, injectable (2.5 mg/mL), 2-mL ampule<br />
Vasopressin, 200 units/10 mL, 10-mL vial<br />
Nitroglycerine, sublingual, 0.4 mg (25/bottle)<br />
Dantrolene sodium injectable (Dantrium), 20 mg, 60-mL vial<br />
Sterile water for injection for Dantrium, 50-mL vial<br />
Intralipid 20%, 250 mL<br />
Lidocaine HCI 2% PFS, 5 mL<br />
Amiodarone, 50 mg/mL, 3 mL<br />
Sodium bicarbonate, 1 mg/mL, 8.4%, 50 mL<br />
Glucose (dextrose) 50%, 50 mL<br />
Calcium chloride 10%, 10 mL<br />
Mannitol 25%, 50 mL<br />
Sterile water, 1000 mL<br />
Furosemide (Lasix), 10 mg/mL, 2-mL vial<br />
Mineral oil<br />
Methylene blue, 1-mL vial<br />
Analgesics<br />
Acetaminophen suppositories, 120 mg, 12/box<br />
Acetaminophen suppositories, 325 mg, 12/box<br />
Acetaminophen suppositories, 650 mg, 12/box<br />
Acetaminophen with codeine solution, 120 mg/12 mg/5 mL/1 tsp<br />
Acetaminophen with codeine tablets, 300 mg/30 mg<br />
Tylenol infant drops, 80 mg/0.8 mL/1 dropperful<br />
Tylenol children’s liquid, 160 mg/5 mL/1 tsp<br />
Tylenol regular strength, 325 tablets<br />
Tylenol liquid (extra strength), 500 mg/tbs (15 mL)<br />
Tylenol caplets (extra strength), 500 mg<br />
Children’s Motrin suspension, 100 mg/5 mL/1 tsp<br />
Motrin infant drops, 50 mg/1.25 mL<br />
Ibuprophen (Motrin IB) 200-mg caplets<br />
For Aspiration Pneumonia<br />
Antibiotic: amoxicillin, 875-mg tablets<br />
Antibiotic: amoxicillin, 400-mg tablets<br />
Inhalation: albuterol, 2.5 mg/3 mL unit-dose vials<br />
Epinephrine, 1:1000, 1-mL ampule<br />
Anti-Inflammatory<br />
Dexamethasone phosphate, injectable, (Decadron), 4 mg/mL,<br />
5-mL vial<br />
Sepsis<br />
Ceftriaxone sodium (Rocephin), 1-g vial<br />
Lidocaine HCL 1%, 50-mg vial<br />
Narcotic Antagonist<br />
Naloxone HCL, 0.4 mg/mL, 1-mL ampule
2178 PART 6 ■ Specific Considerations<br />
syringes should not be used for multiple patients. Emergency drugs<br />
should be drawn up daily and discarded at the end of the day.<br />
Some people argue that because children seldom have ventricular<br />
fibrillation (VF), a defibrillator is not required on trips. The<br />
counter-argument is that children of varying ages, and some<br />
adults, are treated on these trips and can develop VF. Also, supraventricular<br />
and ventricular tachycardia can occur with inadvertent<br />
intravascular injection of epinephrine by the surgeon. Successful<br />
treatment of these dysrhythmias may require cardiac shock. For<br />
these reasons, a defibrillator must be immediately available.<br />
It may be impossible to determine when and if locally available<br />
anesthesia machines have been serviced. Consequently, it is safer<br />
to use anesthesia equipment, including vaporizers, brought by the<br />
team. Portable anesthesia machines are available that have many<br />
of the features of larger machines. These small machines are<br />
durable and function well in hot and cold climates. The vaporizers<br />
are both pressure- and temperature-compensated. Standard halothane,<br />
sevoflurane, and isoflurane vaporizers can be used with<br />
them. Halothane is the most common inhaled anesthetic used in<br />
developing countries but is disappearing from many hospitals in<br />
developed countries. Consequently, many young anesthesiologists<br />
and nurse anesthetists have no experience using it. A medical trip<br />
is not the place to learn to do so. Many trip sites have halothane<br />
vaporizers. If the team’s isoflurane or sevoflurane vaporizers fail,<br />
there is a tendency to try and solve the problem by placing a<br />
different agent in a halothane vaporizer. This may lead to the<br />
delivery of very high concentrations of anesthetic. As pointed out<br />
by Fisher et al., the isoflurane vaporizer can deliver 5% halothane;<br />
an enflurane vaporizer can deliver 10% to 12% halothane when<br />
the vaporizer is set to 7%. 8 The following must be emphasized: We<br />
do not mix drugs and vaporizers at home. We should not do so<br />
on trips. It is too dangerous.<br />
Patient monitoring should include oxygen saturation, body<br />
temperature, heart rate, arterial blood pressure, ECG, and end-tidal<br />
CO 2<br />
. 9 Anesthetic gas concentrations are not measured routinely. A<br />
precordial stethoscope keeps the anesthesiologist attached to the<br />
patient during the case and may help detect respiratory and cardiac<br />
problems early. However, if the operating room is noisy, it may be<br />
difficult to hear cardiac and respiratory sounds with a precordial<br />
stethoscope. A preoperative note should be placed in the patient’s<br />
chart along with a copy of the anesthetic record. Anesthetic records<br />
should contain the same information recorded in the United States,<br />
Canada, and Europe. Returning a copy of the anesthesia record and<br />
the surgery and anesthesia notes to the sponsoring organization<br />
will aid in quality improvement evaluations.<br />
Although it is better to use new circuits and endotracheal tubes<br />
for each patient, most anesthesiologists living in developing<br />
countries routinely reuse circuits and endotracheal tubes. Some<br />
anesthesia providers do this on trips. If they do, the circuits must<br />
be washed with soap and water and dried between cases. Endotracheal<br />
tubes must be cleaned with soap and water and scrubbed<br />
with an endotracheal tube brush to remove all blood and mucus.<br />
Once the tubes are clean, they should be soaked in Cidex OPA<br />
(Johnson and Johnson Co.) for 10 to 20 minutes to sterilize them.<br />
Then they should be rinsed thoroughly with large volumes of<br />
sterile water to remove all traces of the Cidex. Cidex OPA<br />
effectively kills both bacteria and viruses (including the HIV virus)<br />
and is not irritating to tissues. This is a very acceptable protocol for<br />
reuse of endotracheal tubes if it can be followed in a busy<br />
operating room. If the protocol cannot be strictly followed, a new<br />
endotracheal tube is required for each patient.<br />
Wall suction may not be available. If not, portable suction<br />
devices can be used by anesthesiologists for the induction and<br />
awakening from anesthesia and by the surgeons during surgery.<br />
Suction catheters that enter the airway, nose, or mouth should be<br />
discarded or, if they must be reused, they should be thoroughly<br />
cleaned and sterilized after each patient use.<br />
Mechanical ventilators are seldom available in the operating<br />
rooms of most sites. Consequently, most patients breathe spontaneously<br />
throughout surgery. If a Jackson-Reese system is used<br />
to deliver anesthesia, gas inflows should exceed 1.75 to 2 × the<br />
predicted minute ventilation of the patient (minute ventilation =<br />
respiratory rate × tidal volume) to prevent CO 2<br />
rebreathing. These<br />
high flow rates can deplete the oxygen supply of the hospital in<br />
a short time. Circle systems save gas, are low-resistance, and<br />
are economical. Ambu bags should be available in both the PACU<br />
and the operating rooms for emergencies (e.g., when the oxygen<br />
supply fails).<br />
Endotracheal intubation is often required on trips, especially<br />
when the surgery is performed on the face or mouth. RAE tubes<br />
are the standard for oral/facial surgery. Surgeons frequently place a<br />
throat pack during oral surgery to prevent blood from entering the<br />
trachea and to reduce the amount of oxygen and anesthetic gases<br />
that leak into the mouth. Every member of the operating room team<br />
is responsible for assuring that throat packs are removed before<br />
endotracheal tubes are removed. Deaths still occur from retained<br />
throat packs. 10 Since most patients undergoing intraoral surgery<br />
breathe 100% oxygen, there is always the possibility that an airway<br />
fire will occur. The three things needed for a fire are present:<br />
>30% oxygen, a spark source (cautery), and a combustible material<br />
(endotracheal tube). Surgeons must constantly be aware of the<br />
danger of airway fires and prevent the cautery from touching the<br />
endotracheal tube. Laryngeal mask airways (LMAs) are commonly<br />
used to provide an airway and can be used for intermittent positive<br />
pressure ventilation with normal lungs. They do not prevent<br />
aspiration of blood or gastric contents, and they have a large dead<br />
space (Table <strong>133</strong>–3). The end-tidal CO 2<br />
is often 60 to 70 mmHg<br />
during anesthesia when a LMA is used. The smaller the child, the<br />
higher the dead space–induced CO 2<br />
. The elevated CO 2<br />
is usually<br />
not a problem, but can contribute to the total anesthetic level.<br />
ANESTHETIC TECHNIQUES<br />
General Anesthesia<br />
Because many of the patients on trips are children, general<br />
anesthesia is frequently used. In most cases, a mask induction is<br />
done with sevoflurane. Once the patient is asleep, an I.V. is placed<br />
and 1 mg/kg of lidocaine (without epinephrine) plus 0.5 mcg/kg<br />
of fentanyl (or 0.5 mcg/kg of fentanyl and 1 mg/kg of propofol)<br />
can be given to facilitate tracheal intubation. These “cocktails”<br />
prevent or blunt stimulation of the airways associated with<br />
TABLE <strong>133</strong>-3. Dead Space of Laryngeal Mask Airways (LMA)<br />
LMA size<br />
Dead Space (mL)<br />
1.0 6<br />
1.5 7<br />
2.0 7<br />
2.5 13<br />
3.0 22
CHAPTER <strong>133</strong> ■ Implications for Humanitarian Anesthesia 2179<br />
endotracheal intubation. Preventing stimulation of these reflexes<br />
is especially important, because children may have undiagnosed<br />
asthma. Intraoperative narcotic administration reduces the need<br />
to use high concentrations of inhaled anesthetic. Because N 2<br />
O is<br />
seldom available, many anesthesiologists switch from sevoflurane<br />
to isoflurane to reduce cost. Isoflurane may also reduce the<br />
incidence of postoperative dysphoria. 11<br />
Since most patients breathe spontaneously during surgery,<br />
muscle relaxants are seldom used. If muscle relaxants are used, the<br />
patient’s lungs must be ventilated by hand when no mechanical<br />
ventilator is available. Succinylcholine is reserved for airway<br />
emergencies because succinylcholine has been associated with<br />
masseter muscle spasm 12 and death. 13 Spontaneous ventilation<br />
allows the patient to breathe if the endotracheal tube is accidentally<br />
dislodged. It also reduces the amount of oxygen expelled into<br />
the pharynx, lessening the likelihood of an airway fire during oral<br />
surgery. If there is no need to hand ventilate the patient’s lungs,<br />
the anesthesia provider is free to do other things, including give<br />
aid if an emergency occurs with another patient.<br />
Awakening from anesthesia is frequently a dangerous time.<br />
Pharyngeal blood may narrow the nasal passages and cause<br />
laryngospasm. Closure of a cleft palate can significantly reduce<br />
the space available for the tongue, especially if some degree of<br />
Pierre Robin syndrome exists. This increases the likelihood of<br />
upper airway obstruction. Patients should usually be awake before<br />
the endotracheal tube is removed. If no oxygen is available for use<br />
during transport to the PACU, patients should demonstrate<br />
adequate oxygen saturations while breathing room air before<br />
being taken to the PACU.<br />
REGIONAL ANESTHESIA<br />
Spinal, caudal, and epidural anesthesia and peripheral nerve<br />
blocks are commonly used in appropriate patients. Nerve stimulators<br />
are very helpful when performing peripheral nerve blocks,<br />
especially if the needle must go through a burn scar. Ultrasoundguided<br />
blocks are seldom available. Block anesthesia is cost<br />
effective and can reduce operating room turnover time if the block<br />
is placed before the previous surgery ends. An extra anesthesiologist<br />
can help with this. Blocks done in infants and children are<br />
usually done during general anesthesia. Continuous infusion of<br />
local anesthetics or narcotics into epidural catheters for postoperative<br />
pain relief is rarely done because the infrastructure<br />
required for the postoperative care of the patients is lacking.<br />
Single-shot caudal blocks with local anesthetics can be done for<br />
postoperative pain when appropriate. Peripheral nerve blocks are<br />
effective for hand and extremity surgery. Before doing a block one<br />
must be certain that the patient can be adequately monitored<br />
postoperatively for potential complications. Bilateral infraorbital<br />
nerve blocks with 0.25% bupivacaine decrease the postoperative<br />
pain associated with cleft lip repair. Injecting 0.25% bupivacaine<br />
with 1:200,000 epinephrine into the wound edges or bilateral<br />
sphenopalatine ganglion blocks also provide postoperative pain<br />
relief after cleft palate repair. Nerve blocks reduce the need for<br />
postoperative narcotic administration and the risk for airway<br />
obstruction and apnea.<br />
POSTOPERATIVE PAIN RELIEF<br />
Regional blocks effectively reduce postoperative pain. A combination<br />
of a regional block and oral or rectal analgesics are even<br />
more effective. Rectally administered acetaminophen (40 mg/kg)<br />
reduces pain associated with lip and peripheral procedures. Half<br />
of this dose (20 mg/kg) can be administered rectally 4 to 6 hours<br />
later if the patient is not taking oral medications by then. Once<br />
patients are taking oral medications, the dose of acetaminophen<br />
can be reduced to 15 mg/kg with a maximum of 1 gram of drug<br />
every 6 hours. The combination of acetaminophen and codeine is<br />
commonly used to relieve moderate pain. Administering the<br />
appropriate dose of oral acetaminophen (15 mg/kg to 1 g maximum)<br />
provides the correct dose of codeine. Ten percent of people<br />
cannot convert codeine to morphine and get no pain relief from<br />
codeine. They will have some pain relief from the acetaminophen<br />
that accompanies the codeine.<br />
Fentanyl, methadone, and morphine effectively relieve postoperative<br />
pain, but morphine and methadone are unavailable in<br />
many countries. Intravenous nalbuphine 5 to 10 µg/kg provides<br />
mild sedation and good postoperative pain relief. Adequate pain<br />
medication reduces agitation in the PACU and may reduce<br />
unwanted bleeding. Intravenous ketorolac effectively relieves<br />
postoperative pain, but its use is often limited by the perception<br />
that ketorolac causes bleeding.<br />
Many patients in developing countries have never taken a drug<br />
of any kind before arriving at the hospital for surgery. As a<br />
consequence, narcotics may be metabolized more slowly than they<br />
are in patients from developed countries. Reduced narcotic<br />
metabolism may cause respiratory depression or apnea with<br />
commonly-used doses of narcotics in drug-naive children. When<br />
used, narcotics should be titrated to effect. If respiratory depression<br />
occurs, naloxone can be titrated to restore breathing without<br />
reversing pain relief. The beneficial effects of most narcotic<br />
reversal agents last 30 to 45 minutes, whereas narcotic effects may<br />
be longer. Therefore, patients given naloxone must be observed<br />
for more than an hour after administering the drug to assure that<br />
respiratory depression does not recur.<br />
POSTOPERATIVE CARE<br />
Responsibility for patient care in the PACU usually is the purview<br />
of the anesthesiologist, who is responsible for providing pain relief,<br />
correcting airway problems, administering appropriate fluids, and<br />
discharging patients to the ward. Standing PACU orders have their<br />
proponents. However, it is usually better to write specific orders<br />
for each patient, including the type and quantity of fluid to be<br />
administered per hour; the type, dose, and frequency of pain<br />
medication administration; whether and when the hemoglobin<br />
concentration should be determined; who should be called if<br />
problems arise; and how to reach that person (walkie-talkies are<br />
very helpful in for this purpose). The number of PACU beds<br />
usually equals the number of operating tables. Oxygen is required<br />
for each patient. Monitoring includes SaO 2<br />
, arterial blood pressure,<br />
heart rate, respiratory rate, and body temperature. Many<br />
patients are febrile after surgery due to elevated environmental<br />
temperatures or to surgery on infected areas. The latter seeds the<br />
circulation with bacteria. Excessive bleeding should prompt the<br />
PACU nurse to seek help, save the bloody sponges for review by<br />
the surgeons, and determine the patient’s hemoglobin concentration<br />
with a hemoglobinometer. Nurses working in the PACU<br />
usually care for no more than two patients at a time.<br />
The pediatrician/general practitioner assumes care for patients<br />
after they are discharged from the PACU. Many hospital wards in
2180 PART 6 ■ Specific Considerations<br />
developing countries have one nurse for more than 50 patients,<br />
especially at night. Consequently, postoperative care becomes the<br />
purview of the family. The family must assure that their family<br />
member receives sufficient pain medication, that I.V. fluids are<br />
administered and do not run out, and that postoperative wound<br />
care is done. The pediatrician or general practitioner must teach<br />
the parents to provide this care and tell them to contact the ward<br />
nurse if there is a problem. Discharge of patients from the hospital<br />
is the joint responsibility of the pediatrician/general practitioner<br />
and the surgeons. The family should be taught to care for the<br />
patient’s wound, including boiling water and cooling it before using<br />
it to cleanse the wound. Patients should go home with all of the<br />
materials (dressings, tape, antibiotics) needed for their wound care.<br />
Before discharge form the hospital, the family should be given a<br />
date, time, and place to return for suture removal if required.<br />
Before the team arrives, there should be a plan to manage<br />
postoperative complications that occur after patients are discharged<br />
from the hospital, especially when the team is no longer<br />
in the country. A host surgeon who is capable of providing this<br />
care is identified and provided with the resources needed. He or<br />
she usually removes sutures from patients who underwent surgery<br />
during the last week of the trip.<br />
Complicated procedures should be done early in the trip.<br />
Doing large procedures just before the team leaves for a weekend<br />
away or during their last week in the country may lead to<br />
unwanted problems. If possible, all patients should be discharged<br />
from the hospital before the team departs the site.<br />
QUALITY ASSURANCE<br />
Quality assurance (QA) is required to evaluate complications and<br />
untoward events. If a serious event occurs (e.g., death, near death,<br />
need for intensive care, return to the operating room for bleeding),<br />
the complication should be discussed by the team shortly after it<br />
occurs. The discussion should be nonaccusatory and should seek<br />
to determine the facts, much as a root cause analysis is performed<br />
in hospitals in the United States. Once the facts have been gathered<br />
and the cause(s) of the event determined, steps can be taken to<br />
prevent the complication from occurring again. Information<br />
collected should be sent to an interdisciplinary QA committee for<br />
further review. Each person involved in the event should send a<br />
written account of the event to the QA committee. If questions<br />
remain, the head of the committee can call people to obtain more<br />
information. Even events that lead to no harm (e.g., laryngospasm<br />
or return to the operating room for bleeding) should be reported<br />
to the QA committee so the committee can determine if there is a<br />
systemwide problem.<br />
Cardiac and respiratory arrest and death occur more commonly<br />
on trips than in developed countries. Fisher et al. 2 clearly<br />
outlined a method of dealing with these problems. This includes<br />
stopping surgery for a period of time to determine the cause(s) of<br />
the problems and to deal with peoples’ feelings. Not allowing<br />
people to express their feelings may interfere with the care of<br />
subsequent patients. A discussion should take place with family<br />
members shortly after the event so the family understands the<br />
problem and its possible causes. Host colleagues are usually very<br />
helpful with the family, because they understand the language and<br />
the culture and are best able to understand family needs. Also, the<br />
host must remain in the country and will be the one who will have<br />
to deal with the aftermath of these events. Discussions of deaths<br />
with host country sponsors are very important.<br />
EDUCATION<br />
One of the primary goals of a trip is to provide education that will<br />
help local physicians, nurses, and technicians provide surgical care<br />
for the patients themselves. The reasons why local groups cannot<br />
provide this care usually include lack of training, facilities, equipment,<br />
and people. Teams, not just surgeons, are needed. Teaching<br />
someone to do craniofacial surgery without someone who can<br />
provide an airway for the patient or people and facilities to<br />
appropriately care for the patient postoperatively is dangerous. If<br />
the site lacks the resources to do the surgery safely, the parent<br />
organization may be able to help the team succeed by helping the<br />
team acquire the needed equipment and supplies.<br />
Every trip is a chance to teach and learn; education is usually<br />
bidirectional. Physicians and nurses in the countries visited have<br />
devised interesting and ingenious ways of providing care for<br />
patients in systems that lack many things, 14 and we should learn<br />
from them. If we ask local anesthesiologists several months in<br />
advance of the trip if they are interested in didactic or other<br />
teaching, appropriate people can be staffed on the trip and time<br />
can be scheduled for teaching. If the site has residents, it can be<br />
determined if they can work with the team.<br />
What subjects do local physicians and nurses want discussed?<br />
Giving canned lectures that interest us but are of no benefit to the<br />
local doctors and nurses is a waste of time. Almost every site is<br />
interested in the difficult airway, block anesthesia, fluid and<br />
electrolytes, and blood replacement. Local anesthesia providers<br />
want to know how they can provide an airway safely for patients<br />
who have a difficult airway, and they want to know how to do it in<br />
the environment in which they work. There probably is no<br />
fiberoptic bronchoscope within hundreds or thousands of miles.<br />
Most local anesthesiologists have never heard of, let alone seen, a<br />
Glide scope. Teaching how to use these devices is seldom helpful.<br />
Teaching how to use a lightwand, however, especially if the team<br />
can leave a lightwand and stylets with them, may be life-saving. 15<br />
Showing them how to use very expensive anesthetic techniques<br />
may also be a waste of time if the local system cannot afford the<br />
drugs and equipment required. Teaching them to provide appropriate<br />
fluids and electrolytes, postoperative care, and postoperative<br />
pain relief is important. Hospitals in many countries do not<br />
provide narcotics or analgesics for postoperative pain relief. The<br />
patients or their families must buy the drugs from a pharmacy. If<br />
the family cannot afford the drugs, the patient receives no postoperative<br />
pain relief. Teaching practitioners how to use inexpensive<br />
drugs and techniques for pain relief will be advantages to<br />
many people.<br />
Another method of teaching is to send a visiting educator to a<br />
site to teach a specific technique or method. Visiting educators<br />
can be surgeons, anesthesiologists, nurses, or physical or speech<br />
therapists. The goal is to have local physicians, nurses, and therapists<br />
do sufficient procedures with the visiting educator to become<br />
proficient at doing them themselves. Visiting educators are less<br />
expensive because only one or two people go to the site. Like other<br />
trips, the outcome of these programs should be evaluated at the<br />
end of the course and 6 months as well as 1 year later. Did the local<br />
people actually use what they were taught? If so, was it used to<br />
treat the poor? If what they learned was not used, what prevented<br />
them from doing so? Was it lack of facilities, lack of equipment, or<br />
lack of patients? The parent organization many be able to help<br />
correct these deficits.<br />
Local teams can provide surgery for more poor people at a<br />
lower cost than visiting teams. Some organizations make this
CHAPTER <strong>133</strong> ■ Implications for Humanitarian Anesthesia 2181<br />
TABLE <strong>133</strong>-4. Cost of Doing Surgery: Teams From<br />
Developed Countries vs Local Teams During a 5-Year Period<br />
Foreign Teams<br />
Local Teams<br />
4800 patients 5800 patients<br />
$750 per operation $300 per operation<br />
83 surgical expeditions 6 sites<br />
1,162 volunteers 6 surgeons plus local staff<br />
Outcomes—good<br />
Outcomes—good<br />
Data are from Interplast, Mountain View, California.<br />
possible by providing equipment and supplies and by paying teams<br />
to do the surgery. Surgery by local groups costs about half as much<br />
per patient as it does for a team from a developed country to do<br />
the same procedure (Table <strong>133</strong>–4).<br />
By funding local teams, more patients can be treated more<br />
quickly and often at a more appropriate time in development. For<br />
example, cleft lips can be repaired when infants are 3 to 4 months<br />
of age, as they are in developed countries. This assumes that the<br />
anesthesiologists are comfortable and capable of caring for very<br />
young infants. Cleft palates can be repaired before patients begin<br />
to speak (usually at 10–11 months of age), which usually prevents<br />
long-term speech problems. Dislocated hips can be treated early.<br />
Local teams can provide effective follow-up of patients after surgery.<br />
Problems such as palatal fistulas can be dealt with immediately.<br />
Visiting surgical teams many never know a fistula occurred.<br />
How can we monitor the quality of surgery performed by local<br />
teams? One method is to provide the surgeon with a computer<br />
and a digital camera to take pictures pre- and postoperatively and<br />
send them to a group of volunteer surgeons for review. If standards<br />
are met, the local group is paid.<br />
Despite the best efforts of many people, surgery will, unfortunately,<br />
continue to be performed in many places by visiting<br />
surgical teams, because there is no one to train.<br />
Another way to educate is to establish Web sites that are available<br />
to anesthesiologists and surgeons in developing countries.<br />
This provides ongoing education and fosters increased local<br />
capacity. Surgeons can contact the Web site, present a case and the<br />
problem(s) associated with it, and send pictures of the lesion.<br />
Volunteer surgeons can comment on how they would solve the<br />
problem(s), keeping in mind the conditions in the country where<br />
the patient resides. Surgeons working in developing countries can<br />
also comment, and they often have better, more practical solutions<br />
to the problems than volunteers from developed countries. Anesthesiologists<br />
can send potentially difficult cases for discussion, and<br />
volunteer anesthesiologists can describe how they would solve the<br />
problem.<br />
Physicians, nurses, and technicians in most developing<br />
countries often cannot afford textbooks or journals. Providing<br />
them with recent journals is very helpful, assuming there is<br />
someone who can translate the material into the local tongue.<br />
Giving them CDs of recent conferences provides up-to-date information.<br />
In some places, physicians have no stethoscopes. Providing<br />
them with inexpensive stethoscopes is greatly appreciated.<br />
Team members, who return to the same location several years in<br />
a row, will better understand the needs of the physicians, nurses,<br />
and hospital and will be in a better position to help them. Leaving<br />
equipment people cannot use or do not know how to use results<br />
in the equipment being placed in a closet and forgotten. Broken<br />
equipment that cannot be repaired will sit unused, possibly<br />
forever.<br />
The most effective way to teach is to use the 8 or so hours a<br />
day in the operating room for one-on-one discussions and<br />
demonstrations. PowerPoint lectures on a laptop computer can be<br />
used effectively to convey information, assuming you speak the<br />
language or have a translator. There is no better way to find out the<br />
strengths and weaknesses of a person than to spend 8 to 10 hours<br />
with them in the operating room and to ask questions. If you<br />
cannot answer some of their questions, you can go to the Internet,<br />
find the answers, and give the answers to them the next day.<br />
Surgeons can determine if there is someone who can be trained to<br />
lead a group that will perform the surgery themselves. Working<br />
together in the operating room is a great way to build relationships.<br />
CONCLUSION<br />
Trips are an exciting way to improve care in developing countries.<br />
Being able to help patients and to contribute to the development<br />
of physicians, nurses, and technicians is rewarding and is a great<br />
way to give back for all we have. For the right people, medical trip<br />
work can be an exciting part of their practice.<br />
REFERENCES<br />
1. Samuels SI, Wyner J, Brodsky JB, Laub DR. A successful model for<br />
anesthesia and plastic surgery in developing countries. JAMA. 1984;252:<br />
3152–3155.<br />
2. Fisher QA, Nichols D, Stewart FC, et al. Assessing pediatric anesthesia<br />
practices for volunteer medical services abroad. Anesthesiology. 2001;95:<br />
1315–1322.<br />
3. West JB, Schoene RB, Miledge JS. High Altitude Medicine and Physiology.<br />
4th ed. London: Hodder Arnold; 2007.<br />
4. Tait AR, Malviya S. Anesthesia for the child with an upper respiratory<br />
tract infection: still a dilemma? Anesth Analg. 2005;100:59–65.<br />
5. von Ungern-Sternberg BS, Boda K, Schwab C, et al. Laryngeal mask<br />
airway is associated with an increased incidence of adverse respiratory<br />
events in children with recent upper respiratory tract infections.<br />
Anesthesiology. 2007;107:714–719.<br />
6. Gutstein HB, Johnson JL, Heard MB, Gregory GA. Oral ketamine<br />
preanesthetic medication in children. Anesthesiology. 1992;76:28–33.<br />
7. Thummel KE, O’Shea D, Paine MF, et al. Oral first-pass elimination of<br />
midazolam involves both gastrointestinal and hepatic CYP3A-mediated<br />
metabolism. J Clin Pharmacol Ther. 1996;59:491–502.<br />
8. Fisher QA, Politis GD, Tobias JD, et al. Pediatric anesthesia for voluntary<br />
services abroad. Anesth Analg. 2002;95:336–350.<br />
9. Eichhorn JH, Cooper JB, Cullen DJ, et al. Standards for patient<br />
monitoring during anesthesia at Harvard Medical School. JAMA. 1986;<br />
256:1017–1020.<br />
10. Gray H, Brett C, Worthington J. Retained throat packs represent a<br />
potentially catastrophic airway hazard. Anaesth Intensive Care. 2006;34:<br />
119–120.<br />
11. Bortone L, Ingelmo P, Grossi S, et al. Emergence agitation in preschool<br />
children: double-blind, randomized, controlled trial comparing sevoflurane<br />
isoflurane anesthesia. Paediatr Anaesth. 2006;11:1138–1143.<br />
12. Ramirez JA, Cheetam ED, Lawrence AS, Hopkins PM. Suxamethonium,<br />
masseter spasm and later malignant hyperthermia. Anaesthesia. 1998;53:<br />
1111–1116.<br />
13. Rosenberg H, Gronert GA. Intractable cardiac arrest in children given<br />
succinylcholine. Anesthesiology. 1992;77:585–588.<br />
14. Hodges SC, Mijumbi C, Okello M, et al. Anesthesia services in developing<br />
countries: defining the problems. Anaesthesia. 2007;62:4–11.<br />
15. Fox DJ, Matson MD. Management of the difficult pediatric airway in the<br />
austere environment using the lightwand. J Clin Anesth. 1990; 2:123–125.