VACCINE

Vaccine • August 2009
Quadrivalent Human Papillomavirus
recombinant vaccine associated lipoatrophy
Author information
Ojaimi S1, Buttery JP, Korman TM.
Department of Infectious Diseases
Monash Medical Centre, Clayton, Monash University
246 Clayton Rd, Clayton, Victoria, Australia
samojaimi@yahoo.com.au
Abstract
Involutional lipoatrophy, a loss of subcutaneous fat, may be idiopathic,
associated with inflammatory skin conditions, or trauma, and
has also been reported following injections of medications including
insulin, corticosteroids and penicillin. There have also been reports
in association with Diptheria Pertussis Tetanus (DPT) vaccine. We
report on two cases of lipoatrophy associated with the new Quadrivalent
Human Papillomavirus (HPV) recombinant vaccine (Gardasil).
“Involutional lipoatrophy, a loss of subcutaneous fat, may be
idiopathic, associated with inflammatory skin conditions, or
trauma, and has also been reported following injections of
medications including insulin, corticosteroids and penicillin.
There have also been reports in association with Diptheria
Pertussis Tetanus (DPT) vaccine. We report on two cases of
lipoatrophy associated with the new Quadrivalent Human
Papillomavirus (HPV) recombinant vaccine (Gardasil).”
http://www.ncbi.nlm.nih.gov/pubmed/19555713