WHO recommendations on antenatal care for a positive pregnancy experience
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<str<strong>on</strong>g>WHO</str<strong>on</strong>g> <str<strong>on</strong>g>recommendati<strong>on</strong>s</str<strong>on</strong>g> <strong>on</strong> <strong>antenatal</strong> <strong>care</strong> <strong>for</strong> a <strong>positive</strong> <strong>pregnancy</strong> <strong>experience</strong><br />
Type of<br />
interventi<strong>on</strong><br />
Recommendati<strong>on</strong> Type of<br />
recommendati<strong>on</strong><br />
Eight scheduled ANC c<strong>on</strong>tacts<br />
(weeks of gestati<strong>on</strong>)<br />
1 2 3 4 5 6 7 8<br />
(12<br />
weeks)<br />
(20<br />
weeks)<br />
(26<br />
weeks)<br />
(30<br />
weeks)<br />
(34<br />
weeks)<br />
(36<br />
weeks)<br />
(38<br />
weeks)<br />
(40<br />
weeks)<br />
Tetanus toxoid<br />
vaccinati<strong>on</strong><br />
C.5: Tetanus toxoid vaccinati<strong>on</strong> is recommended <strong>for</strong> all pregnant<br />
Recommended X<br />
prevent ne<strong>on</strong>atal mortality from tetanus. y<br />
women, depending <strong>on</strong> previous tetanus vaccinati<strong>on</strong> exposure, to<br />
Malaria<br />
preventi<strong>on</strong>:<br />
Intermittent<br />
preventive<br />
treatment in<br />
<strong>pregnancy</strong> (IPTp)<br />
C.6: In malaria-endemic areas in Africa, intermittent preventive<br />
C<strong>on</strong>text-specific<br />
treatment with sulfadoxine-pyrimethamine (IPTp-SP) is<br />
recommendati<strong>on</strong><br />
recommended <strong>for</strong> all pregnant women. Dosing should start in the<br />
sec<strong>on</strong>d trimester, and doses should be given at least <strong>on</strong>e m<strong>on</strong>th apart,<br />
with the objective of ensuring that at least three doses are received. z<br />
X<br />
(13<br />
weeks)<br />
X X X X X<br />
Pre-exposure<br />
prophylaxis <strong>for</strong><br />
HIV preventi<strong>on</strong><br />
C.7: Oral pre-exposure prophylaxis (PrEP) c<strong>on</strong>taining tenofovir<br />
C<strong>on</strong>text-specific<br />
disoproxil fumarate (TDF) should be offered as an additi<strong>on</strong>al<br />
recommendati<strong>on</strong><br />
preventi<strong>on</strong> choice <strong>for</strong> pregnant women at substantial risk of HIV<br />
infecti<strong>on</strong> as part of combinati<strong>on</strong> preventi<strong>on</strong> approaches. aa<br />
X<br />
D. Interventi<strong>on</strong>s <strong>for</strong> comm<strong>on</strong> physiological symptoms<br />
Nausea and<br />
vomiting<br />
D.1: Ginger, chamomile, vitamin B6 and/or acupuncture are<br />
recommended <strong>for</strong> the relief of nausea in early <strong>pregnancy</strong>, based <strong>on</strong> a<br />
woman’s preferences and available opti<strong>on</strong>s.<br />
Recommended X X X<br />
Heartburn D.2: Advice <strong>on</strong> diet and lifestyle is recommended to prevent and<br />
relieve heartburn in <strong>pregnancy</strong>. Antacid preparati<strong>on</strong>s can be used to<br />
women with troublesome symptoms that are not relieved by lifestyle<br />
modificati<strong>on</strong>.<br />
Recommended X X X X X X X X<br />
y. This recommendati<strong>on</strong> is c<strong>on</strong>sistent with the 2006 <str<strong>on</strong>g>WHO</str<strong>on</strong>g> guideline <strong>on</strong> Maternal immunizati<strong>on</strong> against tetanus (134). The dosing schedule depends <strong>on</strong> the previous tetanus vaccinati<strong>on</strong> exposure; please refer to<br />
Recommendati<strong>on</strong> C.5 <strong>for</strong> details.<br />
z. Integrated from the 2015 <str<strong>on</strong>g>WHO</str<strong>on</strong>g> publicati<strong>on</strong> Guidelines <strong>for</strong> the treatment of malaria, which also states: “<str<strong>on</strong>g>WHO</str<strong>on</strong>g> recommends that, in areas of moderate-to-high malaria transmissi<strong>on</strong> of Africa, IPTp-SP be given to<br />
all pregnant women at each scheduled <strong>antenatal</strong> <strong>care</strong> visit, starting as early as possible in the sec<strong>on</strong>d trimester, provided that the doses of SP are given at least 1 m<strong>on</strong>th apart. <str<strong>on</strong>g>WHO</str<strong>on</strong>g> recommends a package of<br />
interventi<strong>on</strong>s <strong>for</strong> preventing malaria during <strong>pregnancy</strong>, which includes promoti<strong>on</strong> and use of insecticide-treated nets, as well as IPTp-SP” (153). To ensure that pregnant women in endemic areas start IPTp-SP as<br />
early as possible in the sec<strong>on</strong>d trimester, policy-makers should ensure health system c<strong>on</strong>tact with women at 13 weeks of gestati<strong>on</strong>.<br />
aa. Integrated from the 2015 <str<strong>on</strong>g>WHO</str<strong>on</strong>g> publicati<strong>on</strong> Guideline <strong>on</strong> when to start antiretroviral therapy and <strong>on</strong> pre-exposure prophylaxis <strong>for</strong> HIV (99). Substantial risk of HIV infecti<strong>on</strong> is defined by an incidence of HIV infecti<strong>on</strong> in<br />
the absence of PrEP that is sufficiently high (> 3% incidence) to make offering PrEP potentially cost-saving (or cost–effective). Offering PrEP to people at substantial risk of HIV infecti<strong>on</strong> maximizes the benefits<br />
relative to the risks and costs.<br />
114