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WHO recommendations on antenatal care for a positive pregnancy experience

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a list of ANC outcomes was prioritized <strong>for</strong> the whole<br />

ANC period. However, due to important differences<br />

between the types of interventi<strong>on</strong>s and the range of<br />

potential outcomes, these outcomes were further<br />

prioritized separately <strong>for</strong> individual questi<strong>on</strong>s.<br />

In<strong>for</strong>med by the qualitative review of women’s views,<br />

including values and preferences related to ANC, we<br />

included assessment of maternal satisfacti<strong>on</strong> with<br />

a particular interventi<strong>on</strong>, and maternal rating of the<br />

usefulness of a particular interventi<strong>on</strong>.<br />

Throughout the scoping process, the Steering Group<br />

c<strong>on</strong>sulted and engaged with other <str<strong>on</strong>g>WHO</str<strong>on</strong>g> departments<br />

that have issued guidelines with implicati<strong>on</strong>s <strong>for</strong> the<br />

<strong>antenatal</strong> period, incorporating their feedback and<br />

technical expertise into the scoping. The process<br />

and approach were also presented at a number of<br />

meetings and internati<strong>on</strong>al c<strong>on</strong>ferences between<br />

April 2014 and March 2015 to elicit further feedback<br />

from stakeholders.<br />

This scoping and c<strong>on</strong>sultati<strong>on</strong> process led to the<br />

identificati<strong>on</strong> of priority questi<strong>on</strong>s and outcomes<br />

related to the effectiveness of clinical, test accuracy,<br />

and health systems interventi<strong>on</strong>s aimed at achieving<br />

a <strong>positive</strong> <strong>pregnancy</strong> <strong>experience</strong> that includes a<br />

healthy mother and a healthy baby. These questi<strong>on</strong>s<br />

and outcomes are listed in Web annex 1.<br />

the guideline user is referred to the relevant separate<br />

<str<strong>on</strong>g>WHO</str<strong>on</strong>g> guidance via a weblink provided al<strong>on</strong>g with the<br />

“remarks” following each recommendati<strong>on</strong>.<br />

2.8 Focus and approach<br />

To capture and examine the complex nature of the<br />

issues that are important during the ANC period,<br />

within the c<strong>on</strong>text of health systems and the<br />

c<strong>on</strong>tinuum of <strong>care</strong>, the focus of this guideline is the<br />

essential core package of ANC that all pregnant<br />

women and adolescent girls should receive, with the<br />

flexibility to employ a variety of opti<strong>on</strong>s based <strong>on</strong><br />

the c<strong>on</strong>text of different countries (i.e. in terms of the<br />

c<strong>on</strong>tent of the model, who provides the <strong>care</strong>, where<br />

the <strong>care</strong> is provided, and how the <strong>care</strong> is provided to<br />

meet women’s needs). There<strong>for</strong>e, the overarching<br />

questi<strong>on</strong>s addressed by this guideline focused <strong>on</strong> the<br />

following:<br />

• nWhat are the evidence-based practices during the<br />

ANC period <strong>for</strong> improving outcomes related to the<br />

following?<br />

––<br />

nutriti<strong>on</strong>al interventi<strong>on</strong>s (see secti<strong>on</strong> 3.A)<br />

––<br />

maternal and fetal assessment (see secti<strong>on</strong> 3.B)<br />

––<br />

preventive measures (see secti<strong>on</strong> 3.C)<br />

––<br />

interventi<strong>on</strong>s <strong>for</strong> comm<strong>on</strong> physiological<br />

symptoms (see secti<strong>on</strong> 3.D)<br />

<str<strong>on</strong>g>WHO</str<strong>on</strong>g> <str<strong>on</strong>g>recommendati<strong>on</strong>s</str<strong>on</strong>g> <strong>on</strong> <strong>antenatal</strong> <strong>care</strong> <strong>for</strong> a <strong>positive</strong> <strong>pregnancy</strong> <strong>experience</strong><br />

2.7 ANC-related <str<strong>on</strong>g>recommendati<strong>on</strong>s</str<strong>on</strong>g> in other<br />

<str<strong>on</strong>g>WHO</str<strong>on</strong>g> guidelines<br />

To avoid duplicati<strong>on</strong> and ensure harm<strong>on</strong>izati<strong>on</strong> of<br />

<str<strong>on</strong>g>recommendati<strong>on</strong>s</str<strong>on</strong>g> across <str<strong>on</strong>g>WHO</str<strong>on</strong>g> departments and<br />

publicati<strong>on</strong>s, we searched all relevant <str<strong>on</strong>g>WHO</str<strong>on</strong>g> GRCapproved<br />

guidelines and identified 21 guidelines<br />

c<strong>on</strong>taining <str<strong>on</strong>g>recommendati<strong>on</strong>s</str<strong>on</strong>g> relevant to ANC (see<br />

Annex 2). These <str<strong>on</strong>g>recommendati<strong>on</strong>s</str<strong>on</strong>g> were mapped<br />

to the priority questi<strong>on</strong>s <strong>for</strong> this new guideline<br />

and the Steering Group reached out to the <str<strong>on</strong>g>WHO</str<strong>on</strong>g><br />

departments and technical units that had issued the<br />

relevant guidance to engage and collaborate with<br />

them throughout the process of developing this new<br />

ANC guideline. Recommendati<strong>on</strong>s found in other<br />

<str<strong>on</strong>g>WHO</str<strong>on</strong>g> guidelines that related to health promoti<strong>on</strong><br />

and the identificati<strong>on</strong> of risk factors (e.g. smoking,<br />

HIV) during ANC were c<strong>on</strong>sidered to be within the<br />

scope of the guideline, whereas <str<strong>on</strong>g>recommendati<strong>on</strong>s</str<strong>on</strong>g><br />

<strong>on</strong> management and treatment of risk factors,<br />

complicati<strong>on</strong>s and c<strong>on</strong>current diseases were deemed<br />

to be bey<strong>on</strong>d the scope of the guideline; <strong>for</strong> these,<br />

• nHow should these evidence-based practices be<br />

delivered to improve outcomes?<br />

––<br />

health systems interventi<strong>on</strong>s to improve the<br />

utilizati<strong>on</strong> and quality of ANC (see secti<strong>on</strong> 3.E).<br />

The guideline focuses <strong>on</strong> the core ANC clinical<br />

package that all women should receive at routine<br />

ANC visits. The management of identified<br />

complicati<strong>on</strong>s or c<strong>on</strong>current diseases or risk factors<br />

that require additi<strong>on</strong>al treatment or specialist <strong>care</strong><br />

and follow-up is bey<strong>on</strong>d the scope of this guideline.<br />

The DECIDE framework is a tool that has been<br />

developed to help decisi<strong>on</strong>-makers c<strong>on</strong>sider a range<br />

of relevant criteria, including benefits, harms, values,<br />

resources, equity, acceptability and feasibility (17). To<br />

synthesize and examine evidence across the domains<br />

of DECIDE (see secti<strong>on</strong> 2.11), the preparatory work <strong>for</strong><br />

the ANC guideline was organized according to five<br />

work streams, using both quantitative and qualitative<br />

data sources, as summarized in Box 2.<br />

6

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