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Indian Medicinal Plants An Illustrated Dictionary

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stems and bark cause hypotension in<br />

cats and inhibit intestinal movements<br />

in rabbits. The acetone and chloroform<br />

extracts and a resinous fraction<br />

from the alcoholic extract of leaves depress<br />

respiration. The petroleum ether<br />

extract decreases the rate of heartbeat<br />

and contraction in isolated heart of<br />

frog.<br />

<strong>An</strong> alcoholic (50%) extract of the<br />

flowers lowered blood pressure in dogs<br />

and albino rats.<br />

Cyanidin-3-galactoside and cyanidin-3-arbinoside<br />

are present in the<br />

pigments of flowers. The leaves of<br />

var. nilgiricum and var. cinnamonum<br />

contain ursolic acid, friedelin, epifriedelanol,<br />

quercetin. A triterpenoid,<br />

campanulin, has been isolated from<br />

the leaves of var. nilagaricum.<br />

Rhododendron barbatum<br />

Wall. ex G. Don.<br />

Family ◮ Ericaceae.<br />

Habitat ◮ The Himalayas from<br />

Kumaon to Bhutan, extending to<br />

Assam.<br />

English ◮ Giantblood Rhododendron.<br />

Folk ◮ Chimal (Nepal), Kurbak,<br />

Guraans.<br />

Action ◮ Respiratory depressant,<br />

emetic, toxic.<br />

The leaves and flowers gave andromedotoxin<br />

which resembles tertiary<br />

amine veratrum alkaloids, particularly<br />

protoveratrine, in pharmacological<br />

action. Intravenous administration<br />

of andromedotoxin to dogs<br />

Rhododendron campanulatum D. Don. 547<br />

resulted in 20–40% reduction in blood<br />

pressure. It also closely resembles<br />

protoveratrine in its stimulating effect<br />

on the barostatic-pressor-reflexmechanism,<br />

respiratory effects and<br />

emetic action. It produces reflex vasodepressor<br />

responses in intact animals;<br />

in debuffered dogs, it produced<br />

vasopressor responses. It also produced,<br />

both direct and indirect, positive<br />

ionotropic effects, the latter being<br />

more pronounced.<br />

The leaves contain ursolic acid,<br />

alpha-amyrin, epi-friedelinol, campanulin<br />

and hyperoside. Chloroform<br />

extract of the leaves and shoots showed<br />

a depressant action. The honey from<br />

flowers is poisonous; contains andromedotoxin.<br />

Rhododendron campanulatum<br />

D. Don.<br />

Synonym ◮ R. aeruginosum Hk. f.<br />

Family ◮ Ericaceae.<br />

Habitat ◮ Throughout the Himalayas<br />

at altitudes of 2,400–5,200 m.<br />

Folk ◮ Chimal (Kumaon, Nepal),<br />

Gagger vurmi, Nichnai (Kashmir).<br />

Cherailu, Taalis-far.<br />

Action ◮ Leaves—used in chronic<br />

rheumatism and sciatica. As a snuff,<br />

in colds and hemicrania.<br />

The leaves gave a toxic substance<br />

which resembles andromedotoxin; besides<br />

ericolin, ursolic acid, alpha-amyrin,<br />

friedelin, epi-friedelinol, campanulin,<br />

quercitin. The pigments of flowers<br />

contain myricetin and quercetin.<br />

R

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