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Indian Medicinal Plants An Illustrated Dictionary

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492 Piper nigrum Linn.<br />

P<br />

used for enhancing the efficacy of coadministered<br />

medicaments.<br />

Piperine enhanced bioavailability of<br />

hexobarbital, phenytoin, propranolol<br />

and theophylline. (Sharon M. Herr.)<br />

(Piperine is also a component of Piper<br />

nigrum.)<br />

N-isobutyl-deca-trans-2-trans-4dienamide,<br />

isolated from the fruit, exhibited<br />

antitubercular property.<br />

Milk extract of the fruit effectively<br />

reduced passive cutaneous anaphylaxis<br />

in rats. It protected guinea-pigs against<br />

antigen-induced bronchospasm.<br />

In China, Piper longum oil constituents<br />

were reported to inhibit the<br />

increase in serum total cholesterol inducedbytritoninmice.<br />

The root powder exhibited antifertility<br />

activity.<br />

A related species, P. peepuloides<br />

Roxb., is known as Saamvali Peepal.<br />

It is used specifically against obstinate<br />

skin diseases and as a sialagogue.<br />

Dosage ◮ Fruit—1–3 mg (API, Vol.<br />

IV); root—1–3 g powder. (CCRAS.)<br />

Piper nigrum Linn.<br />

Family ◮ Piperaceae.<br />

Habitat ◮ Native of the Indo-<br />

Malaysian region; cultivated<br />

in Western Ghats, Karnataka,<br />

Maharashtra, Assam and Kerala.<br />

English ◮ Black Pepper.<br />

Ayurvedic ◮ Maricha, Vellaja,<br />

Uushna, Suvrrita, Krishnaa.<br />

Unani ◮ Filfil Siyaah, Safed.<br />

Siddha/Tamil ◮ Milagu. Milaguver<br />

(root).<br />

Action ◮ Stimulant, carminative,<br />

diuretic, anticholerin, sialagogue,<br />

bechic, antiasthmatic. Used in<br />

fevers,dyspepsia,flatulence,indigestion,<br />

and as mucous membrane<br />

and gastro-intestinal stimulant. Externally—rubefacient<br />

and stimulant<br />

to the skin. Used as a gargle for sore<br />

throat. Used with ginger and Piper<br />

longum for viral hepatitis.<br />

The fruit yielded piperine, piperatine<br />

and piperidine; amides, piperyline,<br />

piperoleins A and B, and N-isobutyl-cicosa-trans-2-trans-4-dienamide.<br />

The aqueous extract of roasted black<br />

pepper is reported to show cholinomimetic<br />

effect on rat abdominis muscles.<br />

Dosage ◮ Fruit—500 mg to 1 g.<br />

(CCRAS.)<br />

Piper schmidtii Hook. f.<br />

Family ◮ Piperaceae.<br />

Habitat ◮ Assam, Western Ghats,<br />

the Nilgiris and Palni hills above<br />

1,500 m.<br />

English ◮ Nilgiri Pepper.<br />

Action ◮ Carminative.<br />

The neolignan schmiditin, together<br />

with lignin galgravin as well as<br />

friedelin, beta-sitosterol and its beta-<br />

O-glucoside have been isolated from<br />

the extract of aerial parts. The extract<br />

exhibited antiamoebic activity.<br />

Piper sylvaticum Roxb.<br />

Family ◮ Piperaceae.

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