11.12.2012 Views

MEDICINSKI GLASNIK - Aktuelno Ljekarska komora ZE - DO kantona

MEDICINSKI GLASNIK - Aktuelno Ljekarska komora ZE - DO kantona

MEDICINSKI GLASNIK - Aktuelno Ljekarska komora ZE - DO kantona

SHOW MORE
SHOW LESS

Create successful ePaper yourself

Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.

18<br />

Medicinski Glasnik, Volumen 8, Number 1, February 2011<br />

autoregulatory mechanisms (7,8). It has been<br />

reported that epileptic seizures decrease in individuals<br />

practicing yoga (23). This suggests the<br />

contribution of autonomic nervous system. It is<br />

known that the changes in sympathetic activation<br />

occur before and after epileptic seizures, and thus<br />

changes in blood pressure, heart rate and cardiac<br />

output occur. Also, this situation might be in relation<br />

to mortality in epileptic patients and rats<br />

(23,24). Therefore, it is theoretically possible that<br />

changes in the elastic properties of the aorta may<br />

occur from haemodinamyc changes during or<br />

after seizures. Arteryal stiffness has significant<br />

prediction in patients with heart failure, stoke,<br />

REFERENCES<br />

1. Rocamora R, Kurthen M, Lickfett L, Von Oertzen J, Elger<br />

CE. Cardiac asystole in epilepsy: clinical and neurophysiologic<br />

features. Epilepsia 2003; 44:179–85.<br />

2. Devinsky O, Pacia S, Tatambhotla G. Bradycardia and<br />

asystole induced by partial seizures: a case report and<br />

literature review. Neurology 1997; 48:1712–4.<br />

3. Jallon P. Arrhythmogenic seizures. Epilepsia 1997; 38<br />

(suppl 11):S43–7.<br />

4.Lim E CH, Lim S-H, Wilder-Smith E. Brain seizes, heart<br />

ceases: a case of ictal asystole. J Neurol Neurosurg<br />

Psychiatry 2000; 69:557–9.<br />

5. Hunt DP, Tang K. Long QT syndrome presenting as<br />

epileptic seizures in an adult. Emerg Med J 2005;<br />

22:600-1.<br />

6. Demiralp E, Kardesoglu E, Kiralp MZ, Cebeci BS, Keskin<br />

I, Ozmen N, Dursun H. Aortic elasticity in patients<br />

with ankylosing spondylitis. Acta Cardiol 2004;<br />

59:630-4.<br />

7. Laurent S, Boutouyrie P, Asmar R, Gautier I, Laloux B,<br />

Guize L, Ducimetiere P, Benetos A. Aortic stiffness is<br />

an independent predictor of all-cause and cardiovascular<br />

mortality in hypertensive patients. Hypertension<br />

2001; 37:1236-41.<br />

8. Stefanadis C, Dernellis J, Tsiamis E, Stratos C, Diamantopoulos<br />

L, Michaelides A, Toutouzas P. Aortic<br />

stiffness as a risk factor for recurrent acute coronary<br />

events in patients with ischemic heart disease. Eur<br />

Heart J 2000; 21:390-6.<br />

9. Madhavan S, Ooi WL, Cohen H, Alderman MH. Relation<br />

of pulse pressure and blood pressure reduction<br />

to the incidence of myocardial infarction. Hypertension<br />

1994; 3:395-401.<br />

10. Xu C, Zarins CK, Pannaraj PS, Bassiouny HS, Glagov<br />

S. Hypercholesterolemia superimposed by experimental<br />

hypertension induces differential distribution<br />

of collagen and elastin. Arterioscler Thromb Vasc<br />

Biol 2000; 20:2566-72.<br />

11. Metcalf CS, Radvanski PB, Bealer SL. Status epilepticus<br />

produces chronic alterations in cardiac sympathovagal<br />

balance. Epilespsia 2009; 50:747-54.<br />

12. Stefanidis C, Wooley CF, Bush CA, Kolibash AJ, Boudoulas<br />

H. Aortic distensibility abnormalities in coronary<br />

artery disease. Am J Cardiol 1987; 59:1300-4.<br />

renal failure and previous myocardail infarction<br />

too (23,24). We could not find any other study<br />

investigating the elastic properties of the aorta in<br />

epilepsy patients and our study is the first one on<br />

this issue in the literature .<br />

In conclusion, it appears that the elastic characteristics<br />

of the aorta may change in epileptic<br />

patients, with a decrease of the distensibility of<br />

the aorta and an increase of the stiffness. But we<br />

think that more studies are needed in relation to<br />

this subject.<br />

ACKNOWLEDGMENT/DISCLOSURES<br />

Competing interests: none declared.<br />

13. Metcalf CS, Poelzing S, Little JG, Bealer SL. Status<br />

epilepticus induces cardiac myofilament damage and<br />

increased susceptibility to arrhythmias in rats. Am J<br />

Physiol Heart Circ Physiol 2009; 297:H2120-7.<br />

14. Franklin SS, Larson MG, Khan SA, Wong ND, Kannel<br />

WB, Levy D. Does the relation of blood pressure<br />

to coronary heart disease risk change with aging?<br />

The Framingham Heart Study. Circulation 2001;<br />

103:1245–9.<br />

15. Vaccarino V, Berger A, Abramson J, Black H, Setaro J,<br />

Davey J, Krumholz H.Pulse pressure and risk of cardiovascular<br />

events in the systolic hypertension in the<br />

elderly program. Am J Cardiol 2001; 88:980–6.<br />

16. Benetos A, Safar M, Rudnichi A, Smulyan H, Richard,<br />

J-L, Ducimetie`re P,Guize L. Pulse pressure: a predictor<br />

of long-term cardiovascular mortality in a french<br />

male population. Hypertension 1997; 30:1410 –5.<br />

17. Galis ZS, Khatri JJ. Matrix metalloproteinases in vascular<br />

remodeling and atherogenesis. Circ Res 2002;<br />

90:251–62.<br />

18. Akalın F, Tırtır A, Yılmaz Y. Increased QT dispersion<br />

in epileptic children Acta Pediatr 2003; 92:916-20.<br />

19. Lee RT, Kamm RD.Vascular mechanisms for the cardiologists.<br />

J Am Coll Cardiol 1994; 23:1289-95.<br />

20. Lehmann ED, Hopkıns KD, Jones RL, Rudd AG,<br />

Goslıng RG. Aortic distensibility in patients with cerebrovascular<br />

disease. Clin Sci 1995; 89:247-53.<br />

21. Harloff A, Strecker C, Reinhard M, Kollum M, Handke<br />

M, Olschewski M, Weiller C, Hetzel A. Combined<br />

measurement of carotid stiffness and intima-media<br />

thickness improves prediction of complex aortic<br />

plaques in patients with ischemic stroke. Stroke 2006;<br />

37:2708-12<br />

22. Nemes A, De Coo IF, Spruijt L, Smeets HJ, Chinnery<br />

PF, Soliman OI, Geleijnse ML, Ten Cate SJ. Is there<br />

alteration in aortic stiffness in Leber hereditary optic<br />

neuropathy? Eur J Ophthalmol 2008; 18:309-12.<br />

23. Sathyaprabha TN, Satishchandra P, Pradhan C, Sinha<br />

S, Kaveri B, Thennarasu K, Murthy BT, Raju TR.<br />

Modulation of cardiac autonomic balance with adjuvant<br />

yoga therapy in patients with refractory epilepsy.<br />

Epilepsy Behav 2008; 12:245-52.<br />

24. Benetos A, Laurent S, Hoeks AP, Boutouyrie PH, Safar<br />

ME. Arterial alterations with aging and high blood<br />

pressure. A noninvasive study of carotid and femoral<br />

arteries. Arterioscler Thromb 1993; 13:90 –7.

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!