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Staff Members of the Institute of Biochemistry, TU - Institut für ...

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R. Yates, Department <strong>of</strong> <strong>Biochemistry</strong> and Molecular Biology, Faculty <strong>of</strong> Medicine,<br />

University <strong>of</strong> Calgary, Calgary, Canada,<br />

N. Faergeman, Department <strong>of</strong> <strong>Biochemistry</strong> and Molecular Biology, University <strong>of</strong> Sou<strong>the</strong>rn<br />

Denmark, Odense, Denmark<br />

Research Projects:<br />

BM.W_F Genomforschung in Österreich (GEN-AU): Exploring <strong>the</strong> lipolytic proteome.<br />

Phospholipases (GOLD 3 project-Genomics <strong>of</strong> Lipid-associated Disorders, coordinated<br />

by KFU Graz).<br />

FWF Special Research Program (SFB) LIPOTOX (coordinated by KFU Graz): Toxicity <strong>of</strong><br />

oxidized phospholipids in macrophages.<br />

FWF Doctoral Program Molecular Enzymology: Functional enzyme analysis.<br />

FWF EUROCORES-EuroMEMBRANE-OXPHOS-Protein targets and apoptotic signaling <strong>of</strong><br />

oxidized phospholipids<br />

TIG Research center Applied Biocatalysis (coordinated by <strong>TU</strong> Graz): Novel lipases with<br />

specific substrate acceptance.<br />

Invited lectures:<br />

1. Signaling <strong>of</strong> oxidized phospholipids in vascular cells. Fluorescent inhibitors for<br />

functional proteomic analysis <strong>of</strong> lipases. Biocrates, Innsbruck, January 21, 2009.<br />

2. Toxicity <strong>of</strong> oxidized phospholipids in macrophages. COST meeting “Free radicals in<br />

Chemical Biology”, Gniezno, Poland, September 11, 2009.<br />

3. The lipolytic proteomes <strong>of</strong> mouse adipose tissue and liver. Cornell University, Ithaca,<br />

NY, USA, September 22, 2009<br />

4. Fluorescent inhibitors for functional proteomic analysis <strong>of</strong> lipolytic enzymes. Euro Fed<br />

Lipid, Graz, Austria, October 20, 2009<br />

Publications:<br />

1. Rhode S, Grurl R, Brameshuber M, Hermetter A, Schütz GJ<br />

Plasma membrane fluidity affects transient immobilization <strong>of</strong> oxidized phospholipids in<br />

endocytotic sites for subsequent uptake.<br />

J. Biol. Chem. 284, 2258-65, 2009<br />

2. Watschinger K, Keller MA, Hermetter A, Golderer G, Werner-Felmayer G, Werner ER<br />

Glyceryl e<strong>the</strong>r monooxygenase resembles aromatic amino acid hydroxylases in metal<br />

ion and tetrahydrobiopterin dependence.<br />

Biol. Chem. 390, 3-10, 2009<br />

3. Yates RM, Hermetter A, Russell DG<br />

Recording phagosome maturation through <strong>the</strong> real-time spectr<strong>of</strong>luorometric<br />

32

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