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Staff Members of the Institute of Biochemistry, TU - Institut für ...

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Highlights <strong>of</strong> 2009<br />

In April 2009 <strong>the</strong> restructuring <strong>of</strong> <strong>the</strong> Faculty <strong>of</strong> Technical Chemistry, Chemical Engineering<br />

and Biotechnology resulted in a partial reunification <strong>of</strong> <strong>the</strong> <strong><strong>Institut</strong>e</strong> <strong>of</strong> Food Chemistry and<br />

Technology with <strong>the</strong> <strong><strong>Institut</strong>e</strong> <strong>of</strong> <strong>Biochemistry</strong>. During this reshaping Michael Murkovic with<br />

his research group "Chemistry <strong>of</strong> Functional Foods” joined <strong>the</strong> <strong><strong>Institut</strong>e</strong> <strong>of</strong> <strong>Biochemistry</strong>.<br />

The research group <strong>of</strong> Michael Murkovic is mainly interested in<br />

<strong>the</strong> evaluation <strong>of</strong> reaction mechanisms in foods with respect to <strong>the</strong><br />

reactivity <strong>of</strong> antioxidants in relation to <strong>the</strong> formation <strong>of</strong><br />

carcinogenic substance during heating <strong>of</strong> foods. Merging <strong>of</strong> <strong>the</strong><br />

two research units has led to a reinforcement <strong>of</strong> <strong>the</strong> infrastructure<br />

with emphasis on techniques <strong>of</strong> liquid chromatography and <strong>the</strong><br />

identification <strong>of</strong> small molecules.<br />

As in <strong>the</strong> years before, <strong>the</strong> group <strong>of</strong> Peter Macheroux was very active in publishing <strong>the</strong>ir<br />

research results in scientific journals. Among <strong>the</strong> published articles, one was again selected as<br />

best paper <strong>of</strong> <strong>the</strong> week by <strong>the</strong> editors <strong>of</strong> <strong>the</strong> Journal <strong>of</strong> Biological Chemistry (“Hold on to that<br />

flavin” published in July). This publication also marked <strong>the</strong> end <strong>of</strong> a very successful PhD<br />

<strong>the</strong>sis project submitted by Andreas Winkler who left <strong>the</strong> institute and joined <strong>the</strong> Max-Planck-<br />

<strong><strong>Institut</strong>e</strong> <strong>of</strong> Medical Research in Heidelberg, Germany, as an EMBO long-term postdoctoral<br />

fellow. Just before Christmas, Peter Macheroux was awarded <strong>the</strong> Styrian Research Award for<br />

studies on redox-regulated degradation <strong>of</strong> proteins by <strong>the</strong> quinone reductase-proteasome<br />

complex. This project dates back to Peter Macheroux’ early days at <strong>the</strong> institute and was<br />

supported by several outstanding students and postdocs, most notably Sonja Sollner, Andrea<br />

Wagner, Sigrid Deller and Markus Schober.<br />

P. Macheroux (right), Styrian Research Award 2009<br />

4<br />

G. Daum (right), Euro Fed Lipid Conference 2009<br />

As in previous years, research in <strong>the</strong> laboratory <strong>of</strong> Gün<strong>the</strong>r Daum was supported by grants <strong>of</strong><br />

<strong>the</strong> Austrian Science Fund (FWF). In 2009, a new project devoted to “Phosphatidylserine<br />

Decarboxylases <strong>of</strong> <strong>the</strong> Yeast” started with two new graduate students, Martina Gsell and Vid<br />

V. Flis. In 2009, ano<strong>the</strong>r project named ACIB (Austrian Center <strong>of</strong> Industrial Biotechnology)<br />

supported by <strong>the</strong> Austrian Research Promotion Agency (FFG) and industry was approved. In<br />

this joint project Gün<strong>the</strong>r Daum’s group will be involved in applied research devoted to<br />

Pichia pastoris cell biology. Ano<strong>the</strong>r highlight <strong>of</strong> 2009 was <strong>the</strong> Euro Fed Lipid Conference<br />

(European Federation for <strong>the</strong> Science and Technology <strong>of</strong> Lipids) which was held in October

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