Syllabus - MBBS

16 Syllabus MBBS — AIIMS
Environmental biochemistry, cancer and cancer makers
(a) Xenbiotics, interaction with biomolecules, effects, metabolism, detoxication,
(b) Biochemical characteristics of cancer
(c) Environmental pollutants and carcinogenensis.
PRACTICALS
1. Laboratory Instrumentation.
2. Protein fractionation, denaturation, separation of proteins and amino acids.
3. Colour reactions of amino acids and proteins.
4. Estimation of blood analytes: glucose, total cholesterol and HDL cholesterol, uric acid, electrolytes,
urea.
5. Cerebrospinal fluid analyses.
6. Gastric juice analyses.
7. Urine analyses.
8. Amniotic fluid analyses.
9. Enzymes: amylase, lactate dehydrogenase and alkaline phosphatase
10. Liver function tests
11. Renal function tests.
12. Gel electrophoresis of DNA.
13. Immunodiffusion techniques, RIA and ELISA
14. Case-oriented discussions (enzymes, metabolites, function tests)
Biochemistry is taught in two semesters in the 1st year of the MBBS curriculum.
1st Semester : Aug-December
2nd Semester : Jan-June
TEACHING-LEARNING METHODOLOGY
1. Didatic lectures: three and a half hours/week of interactive classroom lectures to facilitate learning
of terminology, principles and concepts. Books and resource material are suggested to encourage
self- directed learning.
2. Tutorials; Two hours/week. Problem based small group discussions, questions-answer sessions,
revision and reinforcement of difficult concepts in tutorial hours. The purpose is to inculcate skills
of reasoning, meaningful approaches to learning and facilitate understanding of the subject.
3. Laboratory exercises: (Biochemistry practicals) three hours/week: a) to substantiate and clarify
theoretical concepts with experimental evidence b) to develop skills of performing basic biochemical
tests important in clinical investigations c) to develope familiarity with biochemical laboratory
instrumentations techniques.
(1) Practical bench work