Syllabus - MBBS

32 Syllabus MBBS — AIIMS
B. TOXICOLOGY
1. GENERAL TOXICOLOGY
History of Toxicology, Definition of Toxicology, Forensic Toxicology, Clinical toxicology and Poison,
Laws in relation to poisons, Medicolegal aspects of poisons, Classification of poisons, Toxicokinetics
and Toxicodynamics, diagnosis of poisoning in living and dead, General principles of management of
poisoning, Antidotes and its types, Medicolegal autopsy in cases of poisoning, preservation and despatch
of viscera for chemical analysis.
2. CLINICAL TOXICOLOGY
Types of poison, Clinical signs and Symptoms, diagnosis, management and medicolegal aspects of :
1. Corrosive poisons – sulphuric acid, phenol ,oxalic acid, nitric acid, hydrochloric acid, organic acids
and alkalies.
2. Irritant non metallic poisons- Phosphorus, Halogens, Organophosphorus, chlorinated hydrocarbons,
miscellaneous preparation & mechanical irritatants.
3. Agricultural poisons- Organophosphorous, Organochlorine. Classification and description of common
insecticides and pesticides used in India
4. Metallic poison - arsenic, lead, iron, copper, zinc, thallium.
5. Animal poisons – snake bite, scorpion bite , wasp, bee, cantherides & toxic fishes.
6. Somniferous poisons – opium & its derivatives, synthetic preparations, pethidine & codeine.
7. Deliriant poisons – Dhatura , hemlock, cannabis, LSD, muscaline & cocaine .
8. Spinal & peripheral nerve poisons – strychnine, curare & domestic poisons – kerosene, cleansing
agents, disinfectants, household medicines.
9. Barbiturate poisoning, drug abuse & common drug overdoses.
10. Vegetable poisons – abrus, ricinus, croton, ergot, capsicum, camphor, argemone, lathyrus &
calotropis.
11. Describe and examine Alcohol poisoning (ethyl & methyl alcohol) and drunkenness, its medicolegal
aspects & benzodiazepine poisoning.
12. Cardiac poisons – HCN, aconite, tobacco, quinine, digitalis and oleander.
13. Asphyxiant poisons – carbon monoxide, , carbon dioxide, hydrogen sulphide, phosgene and phosphine.
14. Definition of food adulteration. Names of common adulterants and general methods of detection for
food adulterants, Common food poisonings- Botulism, Chemical Poisoning, Poisonous Mushrooms
and epidemic dropsy.
3. ENVIRONMENTAL TOXICOLOGY
15. Description of toxic pollution of environment, its medico-legal aspects & toxic hazards of occupation
and industry.
16. Description and medico-legal aspects of poisoning in Workman’s Compensation Act.
4. ANALYTICAL TOXICOLOGY
17. General principles of analytical toxicology and its application in management , prevention and control