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Discover the ESC Textbook of Cardiovascular Imaging 2nd edition

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Chapter 9<br />

<strong>Imaging</strong> during cardiac<br />

interventions<br />

Luis M. Rincón and José L. Zamorano<br />

Contents<br />

Introduction 116<br />

Catheterization laboratory procedures 116<br />

Patent foramen ovale (PFO) 116<br />

Atrial septal defects (ASDs) 117<br />

Ventricular septal defects (VSDs) 119<br />

Echocardiography in trans-septal<br />

catheterization 120<br />

Alcohol septal ablation for hypertrophic<br />

obstructive cardiomyopathy 120<br />

Percutaneous closure <strong>of</strong> left atrial appendage<br />

(LAA) 121<br />

Use <strong>of</strong> echocardiography to guide myocardial<br />

biopsy 123<br />

Use <strong>of</strong> echocardiography to guide<br />

pericardiocentesis 123<br />

Use <strong>of</strong> echocardiography in<br />

electrophysiological procedures 123<br />

Introduction 123<br />

Use <strong>of</strong> echocardiography for cardiac catheter<br />

ablation <strong>of</strong> atrial fibrillation 124<br />

Use <strong>of</strong> echocardiography for other EP ablation<br />

procedures 125<br />

Echocardiography in cardiac resynchronization<br />

therapy procedures 125<br />

References 125<br />

Introduction<br />

Interventional cardiology has evolved during the last decades and the number <strong>of</strong><br />

procedures and indications has increased. This <strong>of</strong>fers a new therapeutic option for<br />

conditions that previously required surgery or that were not amenable to any intervention.<br />

In parallel, cardiac imaging has experienced a similar technological development<br />

and it is commonly required in the catheterization laboratory to evaluate, guide and<br />

improve results <strong>of</strong> several percutaneous procedures [1] ( Table 9.1).<br />

Percutaneous treatment can <strong>of</strong>fer an alternative to surgery in many cases <strong>of</strong> nonvalvular<br />

structural heart diseases, such as atrial septal defects (ASDs) and patent foramen<br />

ovale (PFO), with cardiac imaging routinely used in this context.<br />

Atrial fibrillation with pulmonary veins ablation and left atrial appendage percutaneous<br />

occlusion are commonly guided by cardiac imaging. Other supraventricular and<br />

ventricular tachyarrhythmias ablation procedures performed in the electrophysiology<br />

laboratory (EP) have become clinical settings in which imaging can be useful.<br />

Echocardiography is routinely used for evaluation, guidance, and follow-up <strong>of</strong> patients<br />

undergoing alcohol septal ablation for hypertrophic cardiomyopathy (HCM).<br />

Trans-catheter interventions for valvular heart disease, such as aortic stenosis or<br />

mitral regurgitation, are in constant evolution due to their clinical importance and<br />

high prevalence. The use <strong>of</strong> echocardiography in this context is discussed in a separate<br />

chapter.<br />

Catheterization laboratory procedures<br />

Patent foramen ovale<br />

Diagnosis and indications <strong>of</strong> PFO closure<br />

The foramen ovale plays a role by letting the blood flow across the atrial septum before<br />

birth. Afterwards, right heart pressures and pulmonary resistances decrease due to<br />

breathing and left atrial pressure rises with the beginning <strong>of</strong> pulmonary venous return.<br />

Septum primum is then shoved against the septum secundum, and a permanent fusion<br />

can be seen by the age <strong>of</strong> two in most children. Patent foramen ovale (PFO) can occur as a<br />

result <strong>of</strong> an absence in the fusion <strong>of</strong> the septum primum with the septum secundum, and<br />

can be seen in 24–27% <strong>of</strong> adult population. This persistence can cause a blood flow from<br />

the right to the left atrium whenever the pressure is higher in the first. Approximately 30%<br />

<strong>of</strong> survivors <strong>of</strong> stroke are said to be cryptogenic, and PFO by TEE has been reported to be<br />

present in around 50% in comparison with 24% for the general population. This has led<br />

clinicians to think that the underlying cause <strong>of</strong> the stroke was frequently a PFO. In the last<br />

two years several clinical trials such as RESPECT, PC Trial, and CLOSURE I have tried

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