Gastroenterology Today Autumn 2020
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FEATURE<br />
RETHINKING HOW WE TREAT<br />
CONSTIPATION IN THE UK<br />
Professor Anton Emmanuel, Consultant Gastroenterologist at UCLH and the National Hospital for Neurology & Neurosurgery<br />
In 2018 alone, the UK’s national health system (NHS) saw more<br />
than 52,000 emergency hospital admissions for constipation –<br />
the cost of which adds up to a staggering £71 million per year. 1<br />
Managing such avoidable costs out of the healthcare system<br />
is now even more of a priority given the effects of the Covid-19<br />
pandemic and its aftermath. The NHS urgently needs nonconsultation<br />
pathways to transform sufferers’ lives, yet also<br />
minimise impact on precious resources.<br />
Pyramid” which clearly plots an effective course of treatment. The pyramid<br />
diagram shows that effective treatment of constipation should be done in<br />
incremental stages whereby patients are moved further up the treatment<br />
ladder until their condition comes under control. Starting from the base<br />
layer of the pyramid, patients will first begin treatment with the most<br />
conservative options such as adjustment of diet and fluid intake, lifestyle<br />
alteration oral medications including stool softeners and laxatives, digital<br />
stimulation, suppositories and biofeedback.<br />
GASTROENTEROLOGY TODAY - AUTUMN <strong>2020</strong><br />
We have to start from the question, “why is an easily manageable and<br />
treatable condition like constipation resulting in such a high number<br />
of unplanned emergency hospital admissions?”. The emergency<br />
admission numbers demonstrate the urgent need to revise the current<br />
treatment for constipation and prevent so many cases from escalating<br />
into unwanted admissions. Unplanned hospital visits could certainly be<br />
reduced if symptoms were identified and dealt with at the primary care<br />
stage, but many healthcare professionals lack the right information to<br />
effectively treat the condition. In fact, beyond standard interventions<br />
such as laxatives and dietary changes, there is little supporting<br />
material to guide healthcare professionals through the next stages of<br />
treatment. Drawing on the Bowel Interest Group’s (BIG) newly published<br />
management pathway, this article seeks to help bridge this information<br />
gap by underlining best practices in bowel management.<br />
One of the first barriers to effective treatment of constipation is its<br />
perceived taboo nature. The stigma attached to constipation means that<br />
people are suffering in silence needlessly until the condition becomes<br />
too difficult to bear. Patients are reluctant to share symptoms with their<br />
doctor at the early stages of the condition – with as many as one in<br />
five stating they would be too embarrassed to talk about it at all 2 – and<br />
therefore receive less timely treatment than they should. In parallel, the<br />
high prevalence of these symptoms results in it being perceived by some<br />
healthcare professionals as low risk and of minor significance, further<br />
delaying treatment. Unfortunately, this potentially sets the stage for more<br />
invasive interventions and unwanted hospital admissions in the long run.<br />
With bowel behaviour serving as an important indicator of our health,<br />
it is crucial that we break down this wall and promote more open<br />
conversations about bowel health. Greater awareness about constipation,<br />
as well as correct advice and treatment, will help to make people feel<br />
more comfortable talking to their GP. Without intervention, people with<br />
bowel disorders can suffer from reduced quality of life including feelings<br />
of embarrassment, anxiety and depression – as well as a number of<br />
unwanted side-effects such as urinary tract infections (UTIs). Failure to<br />
deal with symptoms promptly can lead to more complex problems such<br />
as haemorrhoids, anal fissures or rectal prolapse, so it is important to<br />
diagnose and treat the condition as early as possible.<br />
The next step is ensuring that healthcare professionals themselves are<br />
sufficiently informed about treatment options for constipation. In support,<br />
the Bowel Interest Group has developed a ‘Bowel Dysfunction Treatment<br />
If these standard interventions are not effective within the prescribed<br />
three-month period, patients would typically then progress onto the next<br />
stage of treatment: minimally invasive treatment options such as transanal<br />
irrigation (TAI). It is important that the prescribed length of treatment is<br />
consistently adhered to at every level and that patients are moved up the<br />
pyramid once the given timeframe has elapsed. This ensures that patients<br />
suffering from constipation can reach the appropriate therapy level and<br />
resume their normal lives as quickly as possible. The upper layers of the<br />
treatment pyramid are comprised of more invasive treatment options such<br />
as nerve stimulation implants and surgical colonic irrigation. Finally, the<br />
last recourse if these are ineffective, is the creation of a permanent stoma<br />
– which constitutes the peak of the pyramid.<br />
Another important consideration for GPs and Clinical Commissioning<br />
Groups is the cost associated with each therapy. BIG’s pyramid diagram<br />
provides this valuable information, sub-categorized into the one-off cost,<br />
the annual cost and the 7-year cost for each treatment. For instance,<br />
while the cost of standard starting treatment should amount to £2,539,<br />
this figure can reach up to £32,298 over seven years if practitioners do not<br />
progress their patients up the pyramid towards more effective treatment<br />
within the recommended timeframe. 3 Respecting the designated<br />
timeframe for each treatment echelon therefore makes sense from both a<br />
patient-outcome perspective as well as from a financial outlook.<br />
Bowel management in the UK is in need of urgent reform, despite<br />
pockets of excellence scattered across the country. <strong>Today</strong>, constipation<br />
is often perceived as low priority despite having a hugely detrimental<br />
impact on the patients it affects, as well as the financial burden that its<br />
ineffective treatment imposes on the healthcare system. Having the right<br />
pathways in place at the primary level is crucial to ensuring patients<br />
do not require unplanned emergency interventions within already<br />
overstretched facilities. The Covid-19 experience has served to highlight<br />
even further the requirement for non-consultation pathways to transform<br />
sufferers’ lives, yet also minimise impact on precious resources.<br />
Securing these outcomes will take a nationwide effort to rebuild our<br />
understanding of the management of constipation.<br />
Please find the Bowel Interest Group’s full report - Dealing with Chronic<br />
Constipation: Information for General Practitioners:<br />
https://bowelinterestgroup.co.uk/resources/dealing-with-chronicconstipation-information-for-general-practitioners/<br />
12<br />
1<br />
Bowel Interest Group, Cost of Constipation Report, Second edition, 2019<br />
2<br />
Ibid<br />
3<br />
Bowel Interest Group, Dealing with Chronic Constipation: Information for General Practitioners, <strong>2020</strong>