Management of stage Ⅳ rectal cancer - World Journal of ...

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of osteomalacia with oral 25-hydroxyvitamin D. Gastroenterology 1980; 78: 512-517 8 Crawford BA, Kam C, Donaghy AJ, McCaughan GW. The heterogeneity of bone disease in cirrhosis: a multivariate analysis. Osteoporos Int 2003; 14: 987-994 9 Fisher L, Fisher A. Vitamin D and parathyroid hormone in outpatients with noncholestatic chronic liver disease. Clin Gastroenterol Hepatol 2007; 5: 513-520 10 Crawford BA, Labio ED, Strasser SI, McCaughan GW. Vitamin D replacement for cirrhosis-related bone disease. Nat WJG|www.wjgnet.com Malham M et al . Vitamin D deficiency in liver cirrhosis Clin Pract Gastroenterol Hepatol 2006; 3: 689-699 11 Lips P. Which circulating level of 25-hydroxyvitamin D is appropriate? J Steroid Biochem Mol Biol 2004; 89-90: 611-614 12 Maunsell Z, Wright DJ, Rainbow SJ. Routine isotope-dilution liquid chromatography-tandem mass spectrometry assay for simultaneous measurement of the 25-hydroxy metabolites of vitamins D2 and D3. Clin Chem 2005; 51: 1683-1690 13 Pappa HM, Bern E, Kamin D, Grand RJ. Vitamin D status in gastrointestinal and liver disease. Curr Opin Gastroenterol 2008; 24: 176-183 S- Editor Sun H L- Editor Webster JR E- Editor Lin YP 925 February 21, 2011|Volume 17|Issue 7|
Online Submissions: http://www.wjgnet.com/1007-9327office wjg@wjgnet.com doi:10.3748/wjg.v17.i7.926 BRIEF ARTICLE Natural orifice transluminal endoscopic wedge hepatic resection with a water-jet hybrid knife in a non-survival porcine model Hong Shi, Sheng-Jun Jiang, Bin Li, Deng-Ke Fu, Pei Xin, Yong-Guang Wang Hong Shi, Bin Li, Pei Xin, Yong-Guang Wang, Institute of Minimally Invasive Medicine, Tongji University, Shanghai 200092, China Hong Shi, Sheng-Jun Jiang, Bin Li, Deng-Ke Fu, Pei Xin, Yong-Guang Wang, Department of Minimally Invasive Surgery, Beijing Chuiyangliu Hospital, Beijing 100022, China Author contributions: Shi H, Jiang SJ and Wang YG designed the study; Shi H wrote the first draft of the paper; all the authors contributed to the design and interpretation of the study and to the final manuscript. Correspondence to: Yong-Guang Wang, MD, PhD, Department of Minimally Invasive Surgery, Beijing Chuiyangliu Hospital, No. 2, Chuiyangliu South Street, Chaoyang District, Beijing 100022, China. endowang@vip.sina.com Telephone: +86-10-67718822 Fax: +86-10-67711960 Received: October 6, 2010 Revised: November 17, 2010 Accepted: November 24, 2010 Published online: February 21, 2011 Abstract AIM: To explore the feasibility of a water-jet hybrid knife to facilitate wedge hepatic resection using a natural orifice transluminal endoscopic surgery (NOTES) approach in a non-survival porcine model. METHODS: The Erbe Jet2 water-jet system allows a needleless, tissue-selective hydro-dissection with a preselected pressure. Using this system, wedge hepatic resection was performed through three natural routes (trans-anal, trans-vaginal and trans-umbilical) in three female pigs weighing 35 kg under general anesthesia. Entry into the peritoneal cavity was via a 15-mm incision using a hook knife. The targeted liver segment was marked by an APC probe, followed by wedge hepatic resection performed using a water-jet hybrid knife with the aid of a 4-mm transparent distance soft cap mounted onto the tip of the endoscope for holding up the desired plane. The exposed vascular and ductal structures were clipped with Endoclips. Hemostasis was applied to the bleeding WJG|www.wjgnet.com 926 World J Gastroenterol 2011 February 21; 17(7): 926-931 ISSN 1007-9327 (print) ISSN 2219-2840 (online) © 2011 Baishideng. All rights reserved. cut edges of the liver parenchyma by electrocautery. After the procedure, the incision site was left open, and the animal was euthanized followed by necropsy. RESULTS: Using the Erbe Jet2 water-jet system, transanal and trans-vaginal wedge hepatic resection was successfully performed in two pigs without laparoscopic assistance. Trans-umbilical attempt failed due to an unstable operating platform. The incision for peritoneal entry took 1 min, and about 2 h was spent on excision of the liver tissue. The intra-operative blood loss ranged from 100 to 250 mL. Microscopically, the hydro-dissections were relatively precise and gentle, preserving most vessels. CONCLUSION: The Erbe Jet2 water-jet system can safely accomplish non-anatomic wedge hepatic resection in NOTES, which deserves further studies to shorten the dissection time. © 2011 Baishideng. All rights reserved. Key words: Natural orifice transluminal endoscopic surgery; Hepatic resection; Water-jet; Hybrid knife; Triangulation Peer reviewer: Chih-Chi Wang, MD, Department of Surgery, Chang Gung Memorial Hospital-Kaohsiung Medical Center, 123 Ta-Pei Road, Niao-Sung, Kaohsiung 833, Taiwan, China Shi H, Jiang SJ, Li B, Fu DK, Xin P, Wang YG. Natural orifice transluminal endoscopic wedge hepatic resection with a water-jet hybrid knife in a non-survival porcine model. World J Gastroenterol 2011; 17(7): 926-931 Available from: URL: http://www. wjgnet.com/1007-9327/full/v17/i7/926.htm DOI: http://dx.doi. org/10.3748/wjg.v17.i7.926 INTRODUCTION Liver resection, a surgical procedure consisting of he- February 21, 2011|Volume 17|Issue 7|
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World Journal of Gastroenterology W
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Robert JL Fraser, Daw Park Jacob Ge
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Italy Donato F Altomare, Bari Piero
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Fernando Azpiroz, Barcelona Ramon B
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Contents BRIEF ARTICLE WJG|www.wjgn
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Online Submissions: http://www.wjgn
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expressed miRNAs including known on
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Oh et al [73] have shown that upreg
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5 Bardeesy N, DePinho RA. Pancreati
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Fazli L, Motoo Y, Wang Q, Rocchi P,
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standard investigation to confirm t
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proximity to a T3 tumor or nodules
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CONCLUSION Imaging in rectal cancer
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Ronnekleiv-Kelly SM et al . Palliat
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Popek S et al . Neoadjuvant vs adju
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esection [19] . Conversely, approxi
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that option again, than patients wh
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Mulsow J et al . Treatment options
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most significant is ensuring oncolo
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tive times and concerns over both l
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Sharma C et al . Clinical advances
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Page 96 and 97: Table 2 Neuronal density and mean a
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Page 104 and 105: Table 2 Details of patients who nee
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Page 142 and 143: INTRODUCTION Hepatocellular carcino
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Page 151 and 152: Instructions to authors Indexed and
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