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BDI-International Magazine -SUMMER 2021

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(e.g., the University of Sassari, the<br />

University of Brescia, the University<br />

of Cagliari) and the University of<br />

Cincinnati in Ohio.<br />

The researchers in the Radiology study<br />

examined records of 725 patients that<br />

were treated at three key locations in<br />

Italy: the University of Sassari, the<br />

University of Brescia, and<br />

the University of Eastern Piedmont<br />

in Novara. The records show that<br />

15% of the patients were reported as<br />

experiencing neurological symptoms<br />

or disease. Of this group, 59% of<br />

the patients experienced an “altered<br />

mental state,” while 31% experienced<br />

ischemic strokes. In this context,<br />

altered mental state (or altered mental<br />

status) actually encompasses several<br />

notable neurological symptoms, such as<br />

delirium, confusion, and coma.<br />

The aforementioned altered mental<br />

state and ischemic strokes were the two<br />

most common neurological symptoms<br />

in this study. Some less common, but<br />

still notable, reported neurological<br />

symptoms were headache (12%), seizures<br />

(9%), and dizziness (4%). In addition<br />

to this, there were apparent signs of<br />

intracranial hemorrhaging in 6% of the<br />

patients.<br />

The Virus Could Be Damaging<br />

Brain Blood Vessels<br />

Fast forward to the start of<br />

<strong>2021</strong>. Many scientists and<br />

researchers are now shifting<br />

gears to focus on the longterm<br />

neurological effects<br />

of the virus, particularly<br />

in regards to the damage<br />

it inflicts on the brain.<br />

As of yet, numerous studies<br />

have shown no signs of<br />

SARS-CoV-2 in the brains<br />

of people that are infected.<br />

However, several scientists have<br />

observed blood vessel damage in<br />

the postmortem brains of individuals<br />

that had tested positive for COVID-19.<br />

An inflammatory response due to the<br />

virus is thought to have caused this<br />

blood vessel damage, and this has led to<br />

the conclusion that the virus indirectly<br />

attacks the brain.<br />

Dr. Avindra Nath, senior author of<br />

a study and clinical director of the<br />

National Institute of Neurological<br />

Disorders and Stroke (NINDS) at the<br />

National Institutes of Health, stated<br />

that they were initially not expecting to<br />

see such blatant signs of inflammatory<br />

damage:<br />

“We were completely surprised.<br />

Originally, we expected to see<br />

damage that is caused by a<br />

lack of oxygen. Instead, we saw<br />

multifocal areas of damage<br />

that are usually associated with<br />

strokes and neuroinflammatory<br />

diseases.”<br />

Nevertheless, researchers are remain<br />

unsure whether the virus had been<br />

present in the brains at some point in<br />

time. In fact, they are still weighing two<br />

possibilities: the viral copy numbers<br />

were below the level of detection, or the<br />

virus was simply cleared by the time of<br />

death.<br />

Researchers are hesitant to rule out the<br />

presence of the virus in the brain, at least<br />

at some point. This is because like rabies<br />

and mumps, SARS-CoV-2 is technically<br />

a neurotropic virus and thus has the<br />

ability to infect nerve cells.<br />

<strong>BDI</strong> <strong>International</strong> <strong>Magazine</strong> | Page 8<br />

BestDoctorsInsurance.com | Page 9

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