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ABSTRACTS OF THE 21st ANNUAL MEETING OF THE ITALIAN ...

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largest published single surgeon series and it shows<br />

encouraging perioperative, continence and oncologic<br />

outcomes.<br />

140<br />

ROBOT-ASSISTED RADICAL PROSTATECTOMY<br />

IN PATIENTS WITH A HISTORY <strong>OF</strong><br />

ENDOSCOPIC TREATMENT FOR BENIGN<br />

HYPERPLASIA <strong>OF</strong> <strong>THE</strong> PROSTATE<br />

Bernardo Rocco, Pietro Acquati and Giancarlo Albo<br />

Dipartimento di Scienze Chirurgiche Specialistiche Sezione<br />

di Urologia, Università degli Studi di Milano Fondazione<br />

IRCCS Ca’ Granda Ospedale Maggiore Policlinico<br />

U.O. di Urologia, Milano, Italy<br />

Aim: The purpose of this study was to determine whether<br />

previous prostate surgery has an adverse effect on the<br />

perioperative, histopathological and functional outcomes of<br />

robot-assisted radical prostatectomy (RARP). Patients and<br />

Methods: We retrospectively identified 42 patients (Group 1)<br />

who had a history of endoscopic prostate surgery for the<br />

treatment of benign prostate hyperplasia (BPH). We performed<br />

one-to-one matching based upon ten variables (age, BMI,<br />

PSA, SHIM, AUA-SS, c stage, biopsy Gleason score, median<br />

lobe presence, pathological stage and the extent of nervesparing)<br />

using a propensity score matching algorithm to<br />

generate a control group (Group 2). The perioperative,<br />

histopathological and functional outcomes were compared<br />

between these groups. All the patients were evaluated for<br />

continence outcomes, while only those patients who had a<br />

preoperative SHIM score of 17 and had a nerve-sparing<br />

surgery (unilateral, bilateral or partial) were examined for<br />

potency outcomes. Results: The patient demographics after<br />

matching are listed in Table I. The perioperative<br />

histopathological and functional outcomes were evaluated.<br />

There was no statistically significant difference at any point in<br />

time for either continence or potency outcomes Conclusion:<br />

RARP is a safe and effective procedure in patients who have<br />

a history of endoscopic prostate surgery. Although the OR<br />

time is higher in these patients, the PSM rates, complications,<br />

histopathological and functional outcomes are comparable to<br />

those of patients who have no prior prostate surgery.<br />

141<br />

RENAL LEIOMYOMA: A RARE BENIGN<br />

TUMOR <strong>OF</strong> KIDNEY. A CASE REPORT<br />

Cristian Vincenzo Pultrone, Eugenio Brunocilla,<br />

Riccardo Schiavina, Christian Rocca,<br />

Davide Diazzi and Giuseppe Martorana<br />

1884<br />

ANTICANCER RESEARCH 31: 1807-1956 (2011)<br />

Clinica Urologica - Università di Bologna, Policlinico S.<br />

Orsola Malpighi, Bologna, Italy<br />

Aim: We present a case of renal leiomyoma in a 31-year-old<br />

man who presented with hematuria and abdominal pain on the<br />

left flank at the first aid unit of our institution. Case Report:<br />

Ultrasonography and computed tomography (CT) were<br />

performed. A conventional pathological analysis, including<br />

immunohistochemistry, was performed after radical<br />

nephrectomy. Ultrasonography detected enlargement of the<br />

left kidney with a mass occupying the caudal half of the organ,<br />

hypoechoic with irregular central fluid collection and destructuration<br />

of the normal renal echo-structure. The power-<br />

Doppler appearance was hypovascular without visualization<br />

of the renal vein. At CT scan, the lesion was described as a<br />

voluminous heterogeneous mass of 8.6×11 cm in the lower<br />

pole of the left kidney. Before contrast medium injection, the<br />

lesion appeared hyperdense compared with the surrounding<br />

renal parenchyma, with signs of bleeding. It also revealed a<br />

renal pelvis and ureter dilatation with non-flow of contrast<br />

medium into the bladder. Radical nephrectomy was<br />

performed. On gross examination, the mass was well<br />

circumscribed and encapsulated, with a well-defined limit<br />

between the thin rim of renal tissue and the lesion. The outer<br />

surface was lobular and the cut surface showed a solid<br />

whorled white appearance. The tumor was very hard in<br />

consistency. No cystic change, hemorrhage, or necrosis was<br />

evident. On microscopic examination, the lesion showed<br />

fascicles of long spindle cells, showing a whirling pattern with<br />

intervening areas of collagen deposition. Nuclei were regular<br />

oval with bland chromatin. Mitoses were not evident. No<br />

tumor cell pleomorphism, epithelial components or immature<br />

elements were evident on multiple sections that were studied.<br />

On immunohistochemical evaluation, tumor cells were<br />

strongly positive for smooth muscle actin and negative for<br />

cytokeratin and HMB 45. Discussion and Conclusion: Renal<br />

leiomyomas are rare benign tumors of the kidney originating<br />

from muscle cells. A few cases of leiomyoma are described in<br />

the literature. They can be found directly at autopsy as they<br />

are asymptomatic, or diagnosed by the appearance of<br />

symptoms (abdominal/flank pain, hematuria, palpable mass).<br />

Today the widespread use of ultrasonography and CT has<br />

increased the detection of clinically asymptomatic renal<br />

leiomyomas. Ultrasonographic evaluation detects leiomyoma<br />

as a hypoechoic lesion that may appear solid or cystic. At CT<br />

scan leiomyomas appear hyperdense compared to the<br />

surrounding tissue, with density similar to that of muscles. The<br />

differential diagnosis between leiomyoma and other malignant<br />

lesions (above all renal cell carcinoma and leiomyosarcoma) is<br />

still possible only by histological examination. Macroscopically,<br />

leiomyoma is described as a white or red peripheral lesion, well<br />

defined, with a solid aspect and elastic consistence. Color is<br />

related to mass vascularization. Histologically, renal

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