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EAU 2013 - Programme Book - YouMed

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Monday, 18 March - <strong>EAU</strong> <strong>Programme</strong><br />

Abstract Session<br />

14.00 - 15.30 Renal tumours: Drug related basic research<br />

Red Hall 2 - Level N1<br />

Poster Session 80<br />

Chairs: F. Birkhäuser, Berne (CH)<br />

T. Klatte, Vienna (AT)<br />

Poster viewing of 20 minutes. Presentations will take place on stage. Standard presentations are 2 minutes<br />

in length, followed by 2 minutes for discussion. Extended presentations (*) are 4 minutes in length, followed<br />

by 2 minutes for discussion.<br />

975 Pre-clinical trial of a new dual mTOR inhibitor: INK128 for renal cell carcinoma<br />

A. Ingels, A. Thong, M. Saar, M.P. Valta, R. Nolley, J. Santos, H. Zhao, D. Peehl (Stanford, United States of<br />

America)<br />

976 Panobinostat and bortezomib inhibit renal cancer growth in vitro and in vivo by inducing endoplasmic<br />

reticulum stress and ubiquitinated protein accumulation synergistically<br />

A. Sato, T. Asano, K. Ito, T. Asano (Tokorozawa, Japan)<br />

977 Ritonavir, a potent inhibitor of CYP3A4, enhances the anticancer effects of panobinostat in renal cancer<br />

cells in vitro and in vivo<br />

A. Sato, T. Asano, K. Ito, T. Asano (Tokorozawa, Japan)<br />

978 A novel therapeutic approach for renal cell cancer cells using orally available phenylpiperazine derivative<br />

naftopidil<br />

Y. Iwamoto, H. Kanda, M. Kato, T. Sasaki, K. Ishii, K. Arima, T. Shiraishi, Y. Sugimura (Tsu, Japan)<br />

979 Zoledronic acid sensitizes renal cell carcinoma cells to radiation by downregulating STAT1<br />

T. Kijima, F. Koga, Y. Fujii, S. Yoshida, M. Tatokoro, K. Kihara (Tokyo, Japan)<br />

* 980 Optimization of Lutetium-177-G250 radioimmunotherapy in an intraperitoneal clear cell renal cell<br />

carcinoma xenograft model<br />

C.H.J. Muselaers, O.C. Boerman, D.L. Bos, W.J.G. Oyen, E. Oosterwijk, P.F.A. Mulders (Nijmegen, The<br />

Netherlands)<br />

981 Predictive value of angiogenic biomarkers in tuberous sclerosis complex (TSC) patients with renal<br />

angiomyolipoma (AML)<br />

K. Budde, J.C. Kingswood, T. Brechenmacher, K. Stein, D. Chen, J.J. Bissler (Berlin, Germany; Brighton,<br />

United Kingdom; Rueil-Malmaison, France; East Hanover, New Jersey, Cincinnati, Ohio, United States of<br />

America)<br />

982 Sorafenib enhances the anti-tumor effect of anti-CTLA-4 antibody to kidney cancer<br />

T. Motoshima, Y. Komohara, Y. Kawano, Y. Wada, M. Eto (Kumamoto, Japan)<br />

983 Acquired resistance to sunitinib in human renal cell carcinoma cells is mediated by constitutive activation<br />

of signal transduction pathways associated with tumor cell proliferation<br />

H. Miyake, I. Sakai, M. Fujisawa (Kobe, Japan)<br />

* 984 Potential predictive markers for a response to sunitinib and their association with survival of patients with<br />

metastatic renal cell carcinoma<br />

J. Dornbusch, M. Meinhardt, K. Erdmann, A. Zacharis, S. Zastrow, S. Füssel, M.P. Wirth (Dresden, Germany)<br />

<strong>EAU</strong> Milan <strong>2013</strong><br />

293<br />

Monday

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