Page 1 .76 .. 1993 ANNUAL MEETING ABSTRACTS Session A ...

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IJiokI&ically oct;"" &lm:>MIs..nd thio hH hem III impcIVI in de\lelopin& foci .. maIIod:I
for chie;rprepanulon. Then has hem considmoble In!~ in reidallkpoaicb. A mix!",", ofKMn04-CuS04 in ",nux;n, methylene
chloride. in ,he. p.HtflCc of. cuaI)'Iic amount of WlI~r III1d ,olIphatidylinosilol (0.4'.11»"'ere lo",eml.
The moaI abundanl racly ..dd in PE was 18: I 1-40'1.); in PC and SPtll6:O 1-60'1.
eK!I) _ moll abundanl. Ow dac.a suggest iliac lipKe diff.mlliacion ocaon in che
PI' juncti0n5 01 bovine lms fiber cells ond iliac ~ mIIY be .. opcciaI requm,mau
r.,..choIeSICIuI in OJ ~ PE and SPH an: ee IWO _ pI'OnIinem claucs 01
phoIphoIiplds ~ willi ttt.. OJ mriched mernbnne fnctioIl.
es
Sepa .. 11on oICOI\Iuplrei OIe ..... F.ny Adds from Dln"trttu Soun:a In Anlm.]
.nd Human T"bsuts. Sebtlstiaoo 8anni. Mari. AYunta [)asl. Maria Paola Mel••
and FnncelCO P. Comn,iu, Dip. 8;0Io,i. SperimenUlle·Se~. Pllolngi. Sper .. ViQlc
R.,ina Mnrghcrila. 45 09100o..giiari, Italy.
Tht! pracnc:e Ofronjll'Bled diCOC$(CD) in lipid .nvi .......m.m Iw been lliken for
yean! u ."idenee of lipid penuidalion due 10 ee cceerreoce ofilli. 51~lIre in flllty
acid h)'droptn:>~jdel. Small amnunts of CD filly acid i..,....,n an: aI~formed during
partial hydrusenation of fIlS.. A ... consequence. chey an: prucnt in diets prepared
with partially hydn:>aena1CldfllU. M(II'llOVa",il has bcen ....... 1hat co.fany.,id iM>men
art ab50rbed ond dqIoIiIcd in animal MIl hIInIan liuuell. Hence. due 10 !he .
CI8:)n·3: 0.7", C20:40-6; 0.1'.11>.C20:6o-3: 0.]'.11».The ..im oflhis study "'1510
verify iflhis fll CQrnpct-ition and panicul ... ly Mer could Iff tel mcmlnne ionlldlain
poI)'lWalwatcd r.IlY acids (PUfA). Since red blood ""II (R8Cj mcmbnno.
PUFA reflecled brain membrantCQrnposilinll. _1UIdiCd by pI·liquid ch.romaIOJraphy
OLe -')'IiI (capillary column CP Sil 88 SOm ~ 0.23) in .. multicentric
study. filly acid """'J'OJiIions of RBC phoIspiIaIidylethanolamine (PE)in 1_ poup.
oIprenw_ inf ....
IS96.t n; OA:)2
: Group A fed In HM + InAl..FARE(n. 12.,...,.,·_;8W:
...b .. I); Group 8 fed HM ("'ilh.ool lipick modifocacion. only
IlUpplcmcnled ",ilh CltJcin hydrolywc. minerlband du.1rinc-ma/105C!) (n. II. BW;
16J81 ± n; 0....... : 31 ± I ",k). The weigh'pin .....,CQrnpantble in the t_ ,"",ps
IGroup A: 16.2 &lkgld: Group 8: 14.2 gIkgId). The PUFA CQrnpolilinn In Group A
in dlCIC PE did not demo:>mIrate any imporwtl nuauation, and lhere wllSll'l any
IUIOOUIlyfor C20:)n.9 ond CI6:1n-1. AIIhc 37th wk of .... !he two JIOOPS 1II'CI"I'
comparable. In oonclutlon HM fac modifocacion "'ith ALFAR~did not diMurb
mc:mbrane:s' 1ont~lWn PUFA.
Compa .. U"'SludyolSp/llngocny~Un Filly Addlln Er)'lhO"OC"Jln or Prtmalu",
Inflnu Frel wllh Mllernal Milk. Formula or a-Unolenk Acid Enriched formula.
F. B.bin and 8.lHlCOIrIps.INSERM U..58. 60 rue de Nlv.,dlcs. 34090
Montpellier. P. SInb and D. Ricu. N6onaut1ogic. A. Craloln de Paule!. Biochimie A.
and F. Mmdy, OnIdol,C~liGm. Paris. FI"IIICe.
The essenlialily 01 n-3 fany ..-ids: Iw been ""lemivtly documented and .. ve
rUe 10 llUdies 01 «-linolenace supplcmenlacion in formula f«