Hypoplasia-Hyperplasia
Hypoplasia-Hyperplasia
Hypoplasia-Hyperplasia
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Musculoskeletal anomalies<br />
In Moebius syndrome<br />
Club foot (Bilateral)- 33%<br />
Partial syndactyly<br />
Axillary webs<br />
Arthrogryposis<br />
Congenital amputations<br />
<strong>Hypoplasia</strong> of truncal muscles<br />
(Poland’s synd) 15%<br />
Differential diagnosis<br />
Abducens CN (VI) palsy<br />
Brainstem syndromes<br />
Basilar artery thrombosis<br />
Brainstem gliomas<br />
Congenital muscular dystrophy<br />
Congenital myopathies<br />
Myasthenia gravis<br />
Toxic neuropathies<br />
Spinal muscular dystrophy<br />
Myopathies &<br />
Neuropathies are<br />
progressive<br />
Moebius is static but<br />
may be severe or<br />
even lethal (9/26)<br />
Even tend to improve<br />
with time<br />
Inability to smile
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