Common Methods in Microbial Control
Common Methods in Microbial Control
Common Methods in Microbial Control
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Regrowth (recovery)<br />
A rapid resumption of biofilms after antimicrobial<br />
treatment was term<strong>in</strong>ated.<br />
The rema<strong>in</strong><strong>in</strong>g biofilms conta<strong>in</strong> enough viable<br />
organisms.<br />
The residual biofilm enhances transport and sorption<br />
of microbial cells and other compounds to the surface.<br />
Some oxidiz<strong>in</strong>g antimicrobial agents preferentially<br />
removes EPS and not biofilm cells.<br />
EPS is rapidly created by surviv<strong>in</strong>g organisms.<br />
P. aerug<strong>in</strong>osa<br />
Regrowth after -ALA-mediated PDT<br />
1st 2nd<br />
<strong>Control</strong><br />
29<br />
30<br />
Microorganisms<br />
Photosensitizers<br />
Exogenous PS<br />
MC540, MB, HpD<br />
Endogenous PS<br />
-ALA<br />
Natural PS<br />
C-Phycocyan<strong>in</strong><br />
Bacteria<br />
Gram + Gram -<br />
S. aureus P. aerug<strong>in</strong>osa<br />
S. epidermidis E. coli<br />
S. aureus<br />
S. epidermidis<br />
S. aureus<br />
S. epidermidis<br />
P. aerug<strong>in</strong>osa<br />
E. coli<br />
P. aerug<strong>in</strong>osa<br />
E. coli<br />
Gram-positive cell wall Gram-negative cell wall<br />
31<br />
32
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