Understanding Hair Transplants and Hair Loss - Pacific Hair

Increasing the length of the telomere restores the cells to an earlier state of develop-
ment, at least from the standpoint of chromosome length, as young cells have longer
chromosomes . This now permits us to expand the number of different types of stem
cells, since there appears to be a heterogeneous population (Ghazizadeh and Taichman,
2001) . Furthermore, we can increase our understanding of the signaling factors which
are required to grow cells for hair follicle replacement and possible also for replacing the
heart, brain, liver, pancreas, and essentially all organs of the body .
The New Revolution: Plastic Cells
A major advance in biology has just occurred; dynamic Plastic Cells throughout the body
have been discovered . And as we work on creating immortal stem cells, we must integrate
the plastic cell concept into our research programs . Plastic cells can be anything
that they want to be . The view of the adult stem cell is rapidly changing . Adult bone marrow
cells are one form of plastic cells that can not only restore the immune cells of the
blood but can also repopulate brain, blood vessels, heart, liver and muscle (Blau et al .,
2001) . Muscle cells and brain cells may also be a source of blood cells .
It appears that cells can move from one organ to another and differentiate in an environment-dependent
manner . Therefore, a cell can change its morphology as required and
start performing the function as its neighbors dictate . Human hair follicle stem cells appear
to move around to different parts of the follicle (Akiyama, et al ., 2000), although it is
possible that these cells provide evidence for the properties of mobile Plastic Cells . The
signal molecules which determine the fate of these hair follicle Plastic Cells appear to be
beta-1 integrin and epidermal growth factor and the cells have keratin 19 markers . These
findings are very unsettling because it can set the entire practice of medicine upside
down . New therapeutic procedures which use a patient’s own stem cells have already
been performed. In fact, Modex, a Swiss firm established in June 2000, has a produced
called EpiDex, which is a skin product that the company makes from a patient’s own
outer root sheath hair follicle cells . Repair of damaged heart muscles has been accomplished
after intravascular injection of bone-marrow-derived stem cells (Jackson et al.,
2001)
Mineral Ascorbates and the Growth of Plastic Cells
One view that has not been turned upside down is the fundamental need of all cell types
to have the proper amount of mineral ascorbates within their cells . A plastic cell requires
U n d e r s t a n d i n g H a i r T r a n s p l a n t s a n d H a i r L o s s
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