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Management of pregnancy - VA/DoD Clinical Practice Guidelines ...

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<strong>VA</strong>/<strong>DoD</strong> <strong>Clinical</strong> <strong>Practice</strong> Guideline<br />

For Pregnancy <strong>Management</strong><br />

Table 5. Indications for Ultrasonography During Pregnancy<br />

A. Evaluation Of Known Or Suspected<br />

Complications Of Pregnancy:<br />

- confirm intrauterine <strong>pregnancy</strong><br />

- suspected ectopic <strong>pregnancy</strong><br />

- vaginal bleeding<br />

- abdominal and pelvic pain<br />

- maternal pelvic or adnexal masses<br />

- uterine abnormalities<br />

- cervical insufficiency<br />

- suspected amniotic fluid abnormalities<br />

- suspected placental abruption<br />

- premature rupture <strong>of</strong> membranes<br />

- premature labor<br />

- suspected placenta previa<br />

- suspected hydatidiform mole<br />

- evaluate abdominal / pelvic pain or mass<br />

-<br />

B. Pregnancy Dating:<br />

- uncertain gestational age<br />

- assigned gestational age and clinical size<br />

discrepancy<br />

- evaluation <strong>of</strong> suspected multiples<br />

C. As Component <strong>of</strong> Screening For Fetal<br />

Aneuploidy:<br />

- abnormal biochemical markers<br />

- history <strong>of</strong> previous congenital anomaly<br />

- to assess findings that may increase or<br />

decrease the risk <strong>of</strong> aneuploidy<br />

- family, environmental or maternal history<br />

increasing the risk for fetal anomalies<br />

- to screen for fetal anomalies<br />

D. Evaluation <strong>of</strong> Fetal Growth and Well Being:<br />

- confirm cardiac activity<br />

- suspected fetal death<br />

- determine fetal presentation<br />

- fetal condition in late registrants for<br />

prenatal care<br />

- medical conditions posing high risk <strong>of</strong><br />

fetal growth abnormalities<br />

- signs <strong>of</strong> fetal growth abnormality<br />

- follow up <strong>of</strong> known fetal anomaly<br />

E. As adjunct For Procedures:<br />

- amniocentesis, chorionic villus sampling<br />

or fetal surgery<br />

- external cephalic version<br />

- cervical cerclage placement/evaluation<br />

- embryo transfer, or localization and<br />

removal <strong>of</strong> an intrauterine device<br />

RATIONALE<br />

Neither early, late, nor serial ultrasound examination in low risk <strong>pregnancy</strong> has been proven to improve<br />

perinatal morbidity or mortality. <strong>Clinical</strong> trials show that a single mid‐trimester ultrasound examination<br />

detects multiple gestations and congenital malformations earlier in <strong>pregnancy</strong>, but there is currently<br />

insufficient evidence that early detection results in improved short term perinatal outcomes.<br />

Routine second‐trimester ultrasound can lower the rate <strong>of</strong> induction for presumed post‐term <strong>pregnancy</strong>, a<br />

benefit likely to accrue primarily to women with unreliable dates, among whom ultrasound is more accurate<br />

than the unreliable dates for predicting actual date <strong>of</strong> delivery. It is also unclear whether the likeliest<br />

potential benefits <strong>of</strong> routine second‐trimester ultrasound (reduced induction <strong>of</strong> labor for postterm <strong>pregnancy</strong><br />

and increased induced abortions for fetal anomalies) would justify widespread testing from a cost<br />

effectiveness standpoint.<br />

No benefits <strong>of</strong> routine ultrasound examination <strong>of</strong> the fetus in the third trimester have been demonstrated<br />

despite multiple randomized controlled trials. Additional trials <strong>of</strong> third‐trimester placental grading are<br />

needed to adequately evaluate the potential benefits <strong>of</strong> screening for placental appearance.<br />

DISCUSSION<br />

One meta-analysis <strong>of</strong> controlled trials <strong>of</strong> routine versus selective ultrasound evaluation before 24 weeks’ gestation<br />

found that routine screening provided better gestational age assessment (with subsequent lower incidence <strong>of</strong><br />

induction for post-term <strong>pregnancy</strong>), earlier detection <strong>of</strong> multiple gestations, and greater detection <strong>of</strong> unsuspected<br />

Interventions Page - 77

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