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Sanford-Burnham

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MLPCN screening at CPCCG<br />

Detection<br />

Format<br />

63 (50%)<br />

Biochemical<br />

Screens<br />

(22 probes)<br />

48 (38%)<br />

Cell-based<br />

Pathway<br />

Screens<br />

(19 probes)<br />

14<br />

(12%)<br />

High<br />

Content<br />

Screens<br />

(11 probes)<br />

Target<br />

Class<br />

Absorbance<br />

Fluorescence<br />

FRET / TR-FRET<br />

Luminescence<br />

AlphaScreen<br />

Fluorescence Polarization<br />

High Content Screen<br />

NMR<br />

2005-2013<br />

125 Library Screens<br />

52 Probes Identified<br />

Cell Death<br />

Endonuclease<br />

GPCR<br />

Kinase<br />

Phenotypic Pathway<br />

Protease<br />

Protein-Nucleic Acid Interaction<br />

Reporter Gene<br />

Transferase<br />

Cell Proliferation<br />

Glycosylation<br />

Isomerase<br />

Ligase<br />

Phosphatase<br />

Protein Localization<br />

Protein-Protein Interaction<br />

Thioesterase

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