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CDC Article-US Medical Eligibility Criteria for Contraceptive Use, 2010

CDC Article-US Medical Eligibility Criteria for Contraceptive Use, 2010

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Vol. 59 / RR-4 Recommendations and Reports 11<br />

Appendix B<br />

Classifications <strong>for</strong> Combined Hormonal <strong>Contraceptive</strong>s<br />

Combined hormonal contraceptives (CHCs) include lowdose<br />

(containing ≤35 μg ethinyl estradiol [EE]) combined oral<br />

contraceptives (COCs), the combined hormonal patch, and<br />

the combined vaginal ring. The combined hormonal patch and<br />

vaginal ring are relatively new contraceptive methods. Limited<br />

in<strong>for</strong>mation is available about the safety of these methods<br />

among women with specific medical conditions. Moreover,<br />

epidemiologic data on the long-term effects of the combined<br />

hormonal patch and the vaginal ring were not available <strong>for</strong><br />

review. Evidence indicates that the combined hormonal patch<br />

and the combined vaginal ring provide comparable safety<br />

and pharmacokinetic profiles to COCs with similar hormone<br />

<strong>for</strong>mulations (1–33). Pending further studies, the evidence<br />

available <strong>for</strong> recommendations about COCs applies to the<br />

recommendations <strong>for</strong> the combined hormonal patch and vaginal<br />

ring. There<strong>for</strong>e, the patch and ring should have the same<br />

categories (Box) as COCs, except where noted. The assigned<br />

categories should, there<strong>for</strong>e, be considered a preliminary, best<br />

judgement, which will be reevaluated as new data become<br />

available. CHCs do not protect against sexually transmitted<br />

infections (STIs) or human immunodeficiency virus (HIV).<br />

BOX. Categories <strong>for</strong> Classifying Combined Hormonal <strong>Contraceptive</strong>s<br />

1 = A condition <strong>for</strong> which there is no restriction <strong>for</strong> the use of the contraceptive method.<br />

2 = A condition <strong>for</strong> which the advantages of using the method generally outweigh the theoretical or proven risks.<br />

3 = A condition <strong>for</strong> which the theoretical or proven risks usually outweigh the advantages of using the method.<br />

4 = A condition that represents an unacceptable health risk if the contraceptive method is used.<br />

TABLE. Classifications <strong>for</strong> combined hormonal contraceptives, including pill, patch, and ring* †<br />

Condition Category Clarifications/Evidence/Comments<br />

Personal Characteristics and Reproductive History<br />

Pregnancy Not applicable Clarification: <strong>Use</strong> of COCs, P, or R is not required. There is no known harm to the woman, the course of<br />

her pregnancy, or the fetus if COCs, P, or R are inadvertently used during pregnancy.<br />

Age<br />

a. Menarche to

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