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CDC Article-US Medical Eligibility Criteria for Contraceptive Use, 2010

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70 MMWR June 18, <strong>2010</strong><br />

TABLE. (Continued) Classifications <strong>for</strong> barrier methods,* † including condoms, spermicides, and diaphragms/caps<br />

Category<br />

Condition<br />

Condom<br />

Spermicide<br />

Diaphragm/<br />

cap<br />

Clarifications/Evidence/Comments<br />

Drug Interactions<br />

Antiretroviral (ARV) therapy<br />

a. Nucleoside reverse transcriptase inhibitors 1 3 3<br />

(NRTIs)<br />

b. Non-nucleoside reverse transcriptase<br />

1 3 3<br />

inhibitors (NNRTIs)<br />

c. Ritonavir-boosted protease inhibitors 1 3 3<br />

Clarification: No drug interaction between ARV therapy and barrier method<br />

use is known. However, HIV infection and AIDS are classified as Category 3 <strong>for</strong><br />

spermicides and diaphragms (see HIV/AIDS condition above).<br />

Anticonvulsant therapy<br />

a. Certain anticonvulsants (phenytoin, carbamazepine,<br />

1 1 1<br />

barbiturates, primidone, topiramate,<br />

oxcarbazepine)<br />

b. Lamotrigine 1 1 1<br />

Antimicrobial therapy<br />

a. Broad-spectrum antibiotics 1 1 1<br />

b. Antifungals 1 1 1<br />

c. Antiparasitics 1 1 1<br />

d. Rifampicin or rifabutin<br />

therapy<br />

1 1 1<br />

Allergy to latex 3 1 3 Clarification: The condition of allergy to latex does not apply to plastic condoms/<br />

diaphragms.<br />

* Abbreviations: STI = sexually transmitted infection; HIV = human immunodeficiency virus; BMI, body mass index; DVT = deep venous thrombosis; PE = pulmonary embolism;<br />

ARV = antiretroviral; hCG = human chorionic gonadotropin; PID = pelvic inflammatory disease; AIDS = acquired immunodeficiency syndrome; COC = combined oral contraceptive;<br />

NRTI = nucleoside reverse transcriptase inhibitor; NNRTI = non-nucleoside reverse transcriptase inhibitor.<br />

†<br />

If risk exists <strong>for</strong> STI/HIV (including during pregnancy or postpartum), the correct and consistent use of condoms is recommended, either alone or with another contraceptive<br />

method. Consistent and correct use of the male latex condom reduces the risk <strong>for</strong> STIs and HIV transmission. Women with conditions that make pregnancy an unacceptable<br />

risk should be advised that barrier methods <strong>for</strong> pregnancy prevention may not be appropriate <strong>for</strong> those who cannot use them consistently and correctly because of the relatively<br />

higher typical-use failure rates of these methods.<br />

§<br />

Condition that exposes a woman to increased risk as a result of unintended pregnancy.<br />

References<br />

1. The <strong>Criteria</strong> Committee of the New York Heart Association. Nomenclature<br />

and criteria <strong>for</strong> diagnosis of diseses of the heart and great vessels. 9th ed.<br />

Boston, MA: Little, Brown & Co; 1994.<br />

2. Wilkinson D, Ramjee G, Tholandi M, Ruther<strong>for</strong>d G. Nonoxynol-9 <strong>for</strong><br />

preventing vaginal acquisition of HIV infection by women from men.<br />

Cochrane Database Syst Rev 2002;4:CD003939.

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