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Preface<br />
The present dissertation has been carried out during the period 2002-2010 in the<br />
Section of Cariology and Endodontics, Department of Odontology, Faculty of Health<br />
Sciences, University of Copenhagen, Denmark.<br />
I'm deeply grateful to prof., odont. dr. Claes Reit, Institute of Odontology, The<br />
Sahlgrenska Academy at Gothenburg, University of Gothenburg, Sweden, for his<br />
collaboration and support from the very beginning.<br />
The Danish Dental Association and the Copenhagen Dental Association are highly<br />
acknowledged for their positive collaboration, and thanks to all the General Dental<br />
Practitioners. Chief advisor Christian Holt from the Danish Dental Association is<br />
kindly acknowledged for his assistance. The Danish National Health Insurance is<br />
acknowledged for the collaboration with the access to data on claims in dentistry.<br />
Prof. Niels Keiding, Section of Biostatistics, Department of Public Health, University<br />
of Copenhagen, is truly acknowledged for the collaboration about analysis of data<br />
from the questionnaires and the dental service register.<br />
I'm highly grateful to assoc. prof., dr. med. Christian Gluud, head of The Copenhagen<br />
Trial Unit (<strong>CTU</strong>), Centre for Clinical Intervention Research, Rigshospitalet,<br />
Copenhagen University Hospital, Copenhagen, for his great support during the<br />
running of the clinical trials, and together with dr. med. Per Winkel (<strong>CTU</strong>) their<br />
collaboration is highly appreciated, including acknowledgements to the <strong>CTU</strong> staff.<br />
DDS, PhD Student Merete Markvart and DDS Gitte Bruun are acknowledged for the<br />
teamwork and Else Lykke Bjerre for the organizing of many patient visits.<br />
Thanks to my co-authors for all your valuable contributions, I'm very grateful for that.<br />
The staff of the Section of Cariology and Endodontics in Copenhagen is<br />
acknowledged for support during the years. Many thanks for data management and<br />
practical help to secretary Eva-Marie Reinwald, and laboratory technologists Ulla<br />
Larsen and Helga Givskov. Thanks for inspiring discussions with my colleagues of<br />
many years Deputy Head of Department assoc. prof., PhD Kim Ekstrand and assoc.<br />
prof., dr. odont. Vibeke Qvist, and to Senior Dentist Ulla Pallesen and prof., odont. dr.<br />
Svante Twetman for critical comments.<br />
Financial support is acknowledged from the Danish Agency for Sciences and<br />
Innovation and the Danish Regions. Plandent, KerrHawe, 3m Espe, LM-instruments,<br />
Dentsply, DeTrey Dentsply, and Gedr. Brassier are acknowledged for providing trial<br />
products.<br />
Last but not least, thanks to my wife Vibe for always giving me invaluable support<br />
and sharing life with me and our children Mikkel, Marie and Jonas.<br />
Lars Bj0rndal Copenhagen 4 June 2010<br />
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