Quattro 2 User's Guide, issue 2. 6666533 - Waters

Quattro II
User's Guide
Sample Inlet Systems
With the exception of the vacuum lock, all of the permanent inlets are located on the
left hand side of the mass spectrometer. The heated GC transfer line passes through a
computer-controlled oven and enters the ion source through a combined inlet flange
along with the reference inlet and CI gas.
The optional particle beam interface, when fitted, is located to the right of the source.
For all other ionisation techniques, and for solids and involatile liquids, sample is
admitted by probe. Apart from the atmospheric pressure techniques (ESP and APcI)
the probe is inserted through a vacuum lock.
Electrospray Co-axial and Triaxial Probes
The CE Probe
The APcI Probe
The electrospray probe allows sample, solvent and a stream of nebulising gas
(nitrogen), to flow into the electrospray source.
The triaxial flow probe is a direct alternative to the standard co-axial electrospray
probe. It incorporates a sheath tube which allows additional solvent to be transported
to the probe tip and mixed co-axially with the sample flow immediately before
spraying.
The CE probe is used to interface capillary electrophoresis (CE) to a standard
electrospray source. The probe utilises a triaxial flow arrangement whereby the CE
eluent is mixed with a suitable make-up solvent at the probe tip, and then nebulised
using nitrogen gas.
For APcI operation sample, along with the solvent and nebulising gas, is admitted to
the mass spectrometer through the heated APcI probe.
The SFC/APcl Interface
The SFC/APcl interface can be configured for both capillary column supercritical
fluid chromatography (cSFC) and packed column SFC (pSFC).
The Reference Inlet
The reference inlet is a simple reservoir inlet system for the introduction of volatile
liquid reference compounds, such as heptacosa (FC43), for the purpose of calibration.
If required this inlet can also be used to introduce volatile liquid samples. Computer
controlled solenoid valves control the introduction of the sample into the source and
the evacuation of the reservoir.
Instrument Description
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