Exploring Best Practices in the Design of Experiments - JMP
Exploring Best Practices in the Design of Experiments - JMP
Exploring Best Practices in the Design of Experiments - JMP
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Impact? From <strong>the</strong> conclusions:<br />
“Def<strong>in</strong>itive-screen<strong>in</strong>g designs were used to efficiently<br />
select a model describ<strong>in</strong>g <strong>the</strong> formulation <strong>of</strong> a prote<strong>in</strong><br />
under cl<strong>in</strong>ical development. The ability <strong>of</strong> <strong>the</strong> s<strong>in</strong>gle<br />
def<strong>in</strong>itive screen<strong>in</strong>g design to identify and model all <strong>the</strong><br />
active effects obviated <strong>the</strong> need for fur<strong>the</strong>r<br />
experimentation, reduc<strong>in</strong>g <strong>the</strong> total number <strong>of</strong><br />
experimental runs required to 17 from <strong>the</strong> greater than<br />
or equal to 70 runs that would have been necessary<br />
us<strong>in</strong>g <strong>the</strong> traditional screen<strong>in</strong>g/RSM approach.”<br />
4/29/2013