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fluoride in dentistry - usm

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TOXICITY OF FLUORIDE<br />

1. Acute poison<strong>in</strong>g (S/S)<br />

Beg<strong>in</strong> with<strong>in</strong> 30 m<strong>in</strong>utes of <strong>in</strong>gestion<br />

a. GIT<br />

Fluoride <strong>in</strong> the stomach is acted by<br />

hydrochloric acid to form hydrofluoric acid that<br />

is irritable to stomach l<strong>in</strong><strong>in</strong>g, caus<strong>in</strong>g:<br />

- Nausea, vomit<strong>in</strong>g & diarrhea<br />

- Abdom<strong>in</strong>al pa<strong>in</strong><br />

- Increased salivation & thirst<br />

b. Systemic<br />

– CVS : Hyperreflexia, convulsions &<br />

paresthesia<br />

– CVS : Cardiac Failure<br />

– Resp : Paralysis

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