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CONTINUING EDUCATION AND TRAINING<br />
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Scleral contact lenses: indications<br />
and current clinical methods<br />
Ken Pullum, Senior Optometrist, Moorfields Eye<br />
Hospital, London and Oxford Eye Hospital<br />
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Scleral contact lenses (ScCLs) predate rigid corneal and hydrogel lenses by<br />
seven decades, but still have a unique clinical role. The general perception is<br />
that <strong>the</strong>y are only useful in <strong>the</strong> most advanced cases of ectatic corneal disease,<br />
<strong>the</strong> fitting process is cumbersome, <strong>the</strong>y are uncomfortable to wear and <strong>the</strong>y<br />
are <strong>the</strong> cause of hypoxic corneal changes. Professional instruction has become<br />
a low priority in recent years, hence relatively few practitioners have an<br />
understanding of sclerals’ unique advantages or <strong>the</strong> transformation in clinical<br />
methods and manufacturing techniques enabled by <strong>the</strong> introduction of rigid<br />
gas permeable (RGP) materials 1 . Contrary to popular belief, most RGP ScCL fitting<br />
is a straightforward and predictable process, so consequently, <strong>the</strong>y are<br />
also a feasible option for very much lower levels of pathology, ra<strong>the</strong>r than at<br />
a stage which would be described as end point. For example, <strong>the</strong>y may be<br />
offered when patients can still be fitted with corneal lenses, but are<br />
experiencing discomfort and excessive lens mobility.<br />
2 standard CET points<br />
1 CET point<br />
Module 5 Part 4<br />
Specialist contact lens<br />
fitting<br />
About <strong>the</strong> author<br />
Ken Pullum is a Senior<br />
Optometrist at Moorfields<br />
Eye Hospital with a special<br />
interest in medical indications<br />
for contact lenses and<br />
developments in modern<br />
scleral lens practice.<br />
Lens types: fenestrated or<br />
non-ventilated<br />
A ventilated ScCL includes a design feature<br />
which enables fresh oxygenated tears to<br />
access <strong>the</strong> cornea. The expression sealed<br />
has two conflicting meanings in ScCL practice.<br />
In reference to scleral lens categorisation,<br />
it is used to indicate a lens with no<br />
intended means of ventilation incorporated<br />
into <strong>the</strong> design. In a clinical context, its use<br />
describes <strong>the</strong> appearance in situ of a lens<br />
which beds down on <strong>the</strong> sclera so <strong>the</strong>re is<br />
no or only an insignificant tear exchange.<br />
A fenestration 2 is <strong>the</strong> most widely used of<br />
ventilation and can be used for both preformed<br />
and impression lenses. Channels<br />
and slots are alternatives for impression<br />
lenses, but do not function well for preformed<br />
lenses as <strong>the</strong> improved scleral zone<br />
apposition and centration of impression<br />
lenses is required for ei<strong>the</strong>r to function<br />
properly.<br />
It is quite possible that a non-ventilated<br />
coaxial ScCL may have a functional tear<br />
exchange if <strong>the</strong> underlying sclera is irregular,<br />
<strong>the</strong>refore is not sealed. Conversely, if an<br />
intended ventilation feature is non-functional<br />
for some reason, say if a fenestration<br />
is blocked, <strong>the</strong> lens may effectively be<br />
sealed. For clarification, use of <strong>the</strong> term<br />
sealed in <strong>the</strong> remainder of this text refers to<br />
a lens which bears on <strong>the</strong> sclera so that<br />
<strong>the</strong>re is no or insignificant tear exchange,<br />
and non-ventilated to a lens constructed<br />
without a fenestration or o<strong>the</strong>r intentional<br />
means of ventilation.<br />
Lens types: impression or<br />
preformed<br />
ScCLs can be specified after preformed trial<br />
diagnostic lenses of known parameters<br />
have been evaluated in situ, or an individually<br />
bespoke lens may be produced on <strong>the</strong><br />
basis of an eye impression. Impression lenses<br />
can be used virtually irrespective of irregular<br />
topography. Prior to <strong>the</strong> introduction of<br />
RGP materials this was <strong>the</strong> more versatile<br />
system as <strong>the</strong> great majority of <strong>the</strong> cases<br />
were fitted with ScCLs because of irregular<br />
corneal topography.<br />
The introduction of RGP materials shifted<br />
<strong>the</strong> emphasis back to preformed for two<br />
reasons. Firstly, RGP materials are not sufficiently<br />
<strong>the</strong>rmoplastic to be pressed over a<br />
cast, which is <strong>the</strong> simple traditional method<br />
used for PMMA. It is possible to make RGP<br />
impression lenses, but <strong>the</strong> process is much<br />
more cumbersome requiring precision<br />
milling or moulding. Secondly, corneal<br />
swelling studies show that nonventilated<br />
high Dk RGP ScCLs reduce<br />
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corneal swelling to a level comparable to<br />
normal overnight swelling, thus<br />
reintroducing <strong>the</strong> option of fitting ScCLs<br />
without <strong>the</strong> complicating impact of<br />
incorporating a fenestration 3,4,5 .<br />
Advantages and<br />
disadvantages of ScCLs<br />
Advantages<br />
The large size creates a scleral bearing surface<br />
and retains a pre-corneal fluid reservoir<br />
providing optical neutralisation of an astigmatic<br />
or irregular corneal surface and<br />
corneal hydration. Very high powers, up to<br />
+/- 40.00D, are possible because <strong>the</strong>re are<br />
minimal lid traction and centre of gravity<br />
effects. They cannot be dislodged by <strong>the</strong> lids<br />
and are often relatively comfortable even<br />
for <strong>the</strong> unadapted eye because <strong>the</strong> lid<br />
margin is in contact with <strong>the</strong> surface of <strong>the</strong><br />
lens ra<strong>the</strong>r than <strong>the</strong> edge. If RGP non-ventilated<br />
ScCLs are used, corneal contact can be<br />
minimal.<br />
ScCLs, including RGP lenses, can be kept<br />
dry when not being worn. There is no risk of<br />
contaminated storage solutions since none<br />
is used, so <strong>the</strong> risk of infections is reduced.<br />
They are robust, <strong>the</strong> surface can be polished<br />
or resurfaced periodically, and <strong>the</strong>y are not<br />
easily lost. Less dextrous patients may<br />
find <strong>the</strong>m easier to handle because <strong>the</strong>y do<br />
not need to be precariously balanced<br />
on a fingertip.<br />
Disadvantages<br />
While not producing any lid sensation, <strong>the</strong>re<br />
is a feeling and an appearance of bulk, and<br />
some people are intimidated by <strong>the</strong>ir large<br />
size. They cover a large area of <strong>the</strong> anterior<br />
globe, considerably reducing <strong>the</strong> oxygen<br />
available to <strong>the</strong> cornea, although <strong>the</strong> introduction<br />
of RGP materials has led to a major<br />
improvement. Because <strong>the</strong>y are fitted with<br />
corneal clearance, <strong>the</strong> VA and <strong>the</strong> ability of<br />
<strong>the</strong> lens to reduce distortions in ectatic<br />
corneal conditions may be reduced compared<br />
to rigid corneal lenses. However, if an<br />
RGP ScCL can be worn when a corneal lens<br />
cannot, <strong>the</strong> comparison is not valid.<br />
Indications<br />
ScCLs are indicated simply when <strong>the</strong> unique<br />
advantages of ScCLs can be applied. They<br />
can be considered to manage any eye condition<br />
if <strong>the</strong>re is a strong enough reason for<br />
contact lens correction, and in <strong>the</strong> management<br />
of some ocular surface disease. There<br />
have been a number of publications in<br />
recent years describing ScCL applications.<br />
6,7,8,9,10,11,12,13,14,15,16,17,18<br />
Irregular or abnormal<br />
corneal topography<br />
Corneal ectasia<br />
Keratoconus or o<strong>the</strong>r primary corneal<br />
ectasias (PCE) form <strong>the</strong> majority of current<br />
indications for ScCLs. RGP corneal lenses<br />
Figure 2 Irregular corneal topography<br />
as a consequence of a transplant that has<br />
unexpectedly sprung forward. There is a<br />
clear depression in <strong>the</strong> superior<br />
mid-periphery which would be a major<br />
problem for corneal lens fitting. A nonventilated<br />
RGP ScCL is unaffected by a<br />
localised irregularity like this provided it is<br />
sealed on <strong>the</strong> sclera<br />
may be simply impossible to fit in very<br />
advanced cases, for example, as shown in<br />
Figure 1, but <strong>the</strong>re is also an application for<br />
ScCLs when corneal lenses persistently<br />
dislodge, or are not well tolerated due to<br />
excessive mobility or <strong>the</strong> formation of<br />
epi<strong>the</strong>lial erosions.<br />
Corneal transplant<br />
The second largest group for which ScCLs<br />
are indicated are post-corneal transplants if<br />
<strong>the</strong>re is a residual refractive error, or if <strong>the</strong><br />
surface remains irregular, illustrated in<br />
Figure 2. Even if <strong>the</strong> astigmatism is very<br />
high, which still happens sometimes even<br />
with <strong>the</strong> most expert surgery, non-ventilated<br />
RGP ScCL fitting post-transplant is usually<br />
a comparatively straightforward exercise.<br />
The lenses are fitted with full corneal<br />
clearance irrespective of corneal topography,<br />
<strong>the</strong>refore <strong>the</strong> appearance is much <strong>the</strong><br />
same whe<strong>the</strong>r <strong>the</strong> cylinder is 2.00D or in<br />
excess of 20.00D.<br />
Figure 1 Downwardly displaced apex in an advanced keratoconus. Many corneal<br />
lenses were tried, but all dislodged almost immediately. ScCL fitting was a straightforward<br />
process with only two lenses necessary to establish corneal clearance<br />
Corneal trauma or postsurgery<br />
The vision in traumatised eyes with corneal<br />
scarring may be improved with ScCLs if <strong>the</strong><br />
injury has caused irregularities, but has left<br />
some areas of reasonably transparent<br />
cornea in <strong>the</strong> pupillary region. Some cases<br />
of unsuccessful refractive surgery may benefit<br />
if supplementary correction with rigid<br />
contact lenses is helpful in reducing visual<br />
disturbances such as starbursting and<br />
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ghosting. Grossly abnormal topography<br />
would not be expected after refractive surgery,<br />
but some patients remain intolerant of<br />
corneal lenses, in which cases ScCLs<br />
could be tried.<br />
Normal topography with high<br />
refractive errors<br />
ScCLs may be indicated when high power<br />
rigid corneal lenses cause intractable problems<br />
of excessive mobility or poor centration.<br />
They may be used whatever <strong>the</strong><br />
ametropia if <strong>the</strong>re is intolerance to corneal<br />
or hydrogel lens wear in high myopia, or<br />
hypermetropia or significant non-pathological<br />
corneal astigmatism.<br />
Therapeutic or protective<br />
applications<br />
ScCLs uniquely retain a pre-corneal fluid<br />
reservoir providing corneal hydration in serious<br />
dry eye conditions, such as Stevens<br />
Johnson Syndrome or ocular cicatricising<br />
pemphigoid. A ScCL in situ may give an<br />
improved environment for corneal healing<br />
where newly formed epi<strong>the</strong>lium is continually<br />
sloughed away by <strong>the</strong> action of <strong>the</strong> lids,<br />
or may prevent tear film evaporation with<br />
poor lid closure or lid absence. The lens<br />
retains a fluid reservoir which maintains<br />
some degree of corneal hydration and<br />
protects <strong>the</strong> cornea from trichiasis and lid<br />
margin keratinisation, and <strong>the</strong> front surface<br />
provides hugely improved refracting surface,<br />
giving a considerable visual benefit.<br />
There is also an application in less severe<br />
dry eye or tears dysfunction pathology.<br />
Sometimes <strong>the</strong> patient may describe very distressing<br />
and disproportionate ocular discomfort<br />
with very little visible corneal disruption.<br />
Mucus filaments adherent to <strong>the</strong> cornea are<br />
very painful when <strong>the</strong>y pull on <strong>the</strong> epi<strong>the</strong>lium<br />
or finally detach, but wave freely in <strong>the</strong> precorneal<br />
fluid reservoir behind a ScCL, and<br />
appear to float off into <strong>the</strong> fluid pool with little<br />
discomfort. ScCLs may be used as a prop<br />
for some cases of ptosis.<br />
Cosmetic shells<br />
A realistic iris can be encapsulated into<br />
PMMA scleral shells to mask unsightly blind<br />
eyes, or to relieve intractable diplopia or<br />
glare in cases of aniridia.<br />
Recreational or occupational<br />
applications<br />
Particles behind rigid corneal lenses in dusty<br />
work place environments are very troublesome.<br />
ScCLs eliminate this problem almost<br />
entirely. Most recreational activities are satisfactorily<br />
managed with <strong>the</strong> use of hydrogel<br />
lenses, but ScCLs are still indicated on<br />
occasions for contact or water sports.<br />
ScCL fitting options<br />
Ventilation by some means is a prerequisite<br />
for PMMA lenses whe<strong>the</strong>r impression or preformed,<br />
but non-ventilated designs are <strong>the</strong><br />
preferred option for RGP. Some limitations<br />
still remain for irregular ocular topography<br />
with RGP preformed sclerals, but considerably<br />
more irregular eyes can be fitted using<br />
preformed RGP sclerals because of <strong>the</strong> tear<br />
reservoir compared to fenestrated PMMA.<br />
Impression lenses of some kind can be used<br />
virtually irrespective of irregular topography.<br />
All <strong>the</strong> following alternatives are possible,<br />
and have different applications.<br />
RGP<br />
RGP sclerals should now be considered <strong>the</strong><br />
first choice for <strong>the</strong> great majority of ScCL<br />
cases. Some long-term wearers have worn<br />
<strong>the</strong> lenses for over 50 years, so <strong>the</strong>se should<br />
be considered a long-term option for most<br />
new referrals. As <strong>the</strong> great majority of ScCL<br />
referrals are for PCE or corneal transplant, it is<br />
crucial to minimise <strong>the</strong> risk of corneal hypoxia.<br />
A transplant may have to be a future management<br />
option for any PCE referred for ScCL<br />
fitting. If so, corneal neovascularisation, while<br />
not necessarily sight-threatening in its own<br />
right in <strong>the</strong> early stages, may increase <strong>the</strong> risk<br />
of transplant rejection.<br />
Preformed non-ventilated RGP can be<br />
used for <strong>the</strong> great majority of cases, irrespective<br />
of corneal topography. There are more<br />
potential problems with <strong>the</strong> scleral topography,<br />
but if <strong>the</strong> scleral zone is well enough<br />
sealed, a pre-corneal fluid reservoir is<br />
retained without bubbles and with minimal<br />
settling on <strong>the</strong> globe. The optimum clearance<br />
at <strong>the</strong> visual axis is approximately 0.25mm,<br />
but can be more than twice that value at <strong>the</strong><br />
limbus in some sectors without causing any<br />
problems provided it remains air free.<br />
The principal problem with preformed<br />
non-ventilated RGP ScCLs is that <strong>the</strong>y have<br />
to be inserted filled with saline. This requires<br />
keeping <strong>the</strong> lens horizontal at <strong>the</strong> moment<br />
of insertion, so it is necessary also to have<br />
<strong>the</strong> patient’s head horizontal and facing <strong>the</strong><br />
floor. This is a more difficult task for<br />
patients, and sometimes for <strong>the</strong> practitioner<br />
as well, compared to <strong>the</strong> relatively simple<br />
procedure for inserting a fenestrated lens,<br />
which can be inserted with <strong>the</strong> head in <strong>the</strong><br />
normal upright posture.<br />
Preformed fenestrated RGP is indicated<br />
if a fenestration is beneficial, for<br />
example, if retention of <strong>the</strong> pre-corneal fluid<br />
reservoir at <strong>the</strong> moment of insertion is<br />
impossible. However, <strong>the</strong>re is a serious limitation<br />
because air bubbles are admitted into<br />
<strong>the</strong> pre-corneal fluid reservoir and cross <strong>the</strong><br />
visual axis if <strong>the</strong> pre-corneal fluid reservoir<br />
depth is greater than 0.1mm. It is unlikely<br />
that a tear pool of uniformly shallow depth<br />
can be maintained with even just a moderately<br />
irregular corneal topography.<br />
Impression non-ventilated RGP is an<br />
option if <strong>the</strong>re is an intractable problem<br />
retaining an air free pre-corneal fluid reservoir<br />
with a non-ventilated preformed<br />
design. The ultimate fitting target is a flush<br />
back surface for <strong>the</strong> scleral zone and an<br />
optic zone clearance similar to that for a<br />
non-ventilated preformed RGP. As <strong>the</strong> scleral<br />
zone is fabricated from an eye impression,<br />
a very good alignment can be expected with<br />
effective sealing on <strong>the</strong> scleral zone, hence<br />
<strong>the</strong>re is scope for increasing <strong>the</strong> optic zone<br />
clearance with a good prospect of retaining<br />
a pre-corneal fluid reservoir.<br />
Impression fenestrated RGP is a major<br />
undertaking because it is a departure from<br />
mainstream manufacturing and, in<br />
addition, requires very precise fabrication of<br />
<strong>the</strong> back surface to keep a uniform depth of<br />
<strong>the</strong> pre-corneal fluid reservoir. However,<br />
<strong>the</strong>re may be a better chance than with a<br />
fenestrated preformed RGP lens because<br />
<strong>the</strong> optic zone is individually fabricated from<br />
<strong>the</strong> exact shape of <strong>the</strong> eye.<br />
PMMA<br />
PMMA ScCLs still have a role to play but<br />
<strong>the</strong>re is an acknowledged long-term threat of<br />
hypoxic corneal changes, so <strong>the</strong>se would not<br />
normally be <strong>the</strong> first choice for new ScCL<br />
wearers. However, if a PMMA lens has been<br />
worn successfully for some years without significant<br />
sequelae, <strong>the</strong>re is no reason for a<br />
change is to be made. Most impression<br />
PMMA lenses for moderate or advanced<br />
corneal ectasias were ventilated, hence <strong>the</strong><br />
initial clearance at <strong>the</strong> visual axis could not be<br />
much more than 0.1mm. After a period of<br />
settling on <strong>the</strong> globe, an almost universal<br />
occurrence with a ventilated lens, <strong>the</strong> result<br />
was apical contact. The author’s observation<br />
is that contact is better tolerated in PMMA<br />
than with RGP materials. The probable explanation<br />
is <strong>the</strong> increased co-efficient of friction<br />
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for RGP materials compared to PMMA.<br />
For <strong>the</strong> same reason, <strong>the</strong>re may be more<br />
surface/tarsal plate interaction with RGP<br />
compared to PMMA. Fur<strong>the</strong>rmore, <strong>the</strong> visual<br />
performance in terms of visual acuity,<br />
contrast and reduction of distortions or<br />
ghosting is reduced when <strong>the</strong>re is a visual<br />
axis contact zone.<br />
Impression ventilated PMMA proved to<br />
be a successful option in many cases before<br />
RGP materials were available. A ventilated<br />
impression PMMA lens is easier to produce<br />
than RGP due to its superior <strong>the</strong>rmoplasticity,<br />
and because it can be cut and polished<br />
with minimum risk of irreparable damage.<br />
Impression ventilated ScCLs very often have<br />
central corneal contact zones after settling<br />
back, irrespective of <strong>the</strong> material. If so, PMMA<br />
is more likely to be tolerated. Impression<br />
PMMA is arguably <strong>the</strong> method of choice for<br />
elderly aphakes. Centration is optimised with<br />
<strong>the</strong> impression method of fitting as <strong>the</strong>re is a<br />
near glove fit on <strong>the</strong> sclera. Thus <strong>the</strong> front<br />
optic can be sited over <strong>the</strong> visual axis to<br />
minimise aberrations.<br />
Preformed fenestrated PMMA may be<br />
a preferable option to RGP fenestrated<br />
because it may be fitted with less initial<br />
clearance so that apical contact following<br />
any settling on <strong>the</strong> globe is better tolerated<br />
than if an RGP lens is similarly fitted.<br />
However, <strong>the</strong> chances of a successful outcome<br />
with a moderately or advanced ectasia<br />
and irregular topography remain limited<br />
for <strong>the</strong> reasons discussed previously.<br />
Impression or preformed nonventilated<br />
PMMA has no place for long<br />
term wear as <strong>the</strong> onset of hypoxia is very<br />
rapid. However, it is worth remembering that<br />
advanced keratoconus causes extremely poor<br />
unaided vision and spectacles may do next to<br />
nothing by way of correction.<br />
Therefore, all contact lens options should<br />
be borne in mind. If good vision to deal with<br />
a particular task is urgently required for a<br />
few minutes, a non-ventilated PMMA lens<br />
provides just that.<br />
The fitting and production are <strong>the</strong> simplest<br />
for all scleral lens types provided <strong>the</strong><br />
scleral zone seals adequately on <strong>the</strong> sclera,<br />
which should be <strong>the</strong> case following an<br />
impression lens if not with a preformed lens.<br />
Preformed non-ventilated RGP<br />
ScCL fitting<br />
PMMA ScCLs, whe<strong>the</strong>r preformed or<br />
impression of preformed, are comparatively<br />
infrequently required nowadays. The fitting<br />
Figure 3 Optimum preformed lens fitting with scleral alignment and optic zone clearance<br />
Figure 4 Steep fitting scleral zone<br />
illustrating fluorescein encroaching almost<br />
to <strong>the</strong> periphery of <strong>the</strong> lens. There is also a<br />
small amount of blanching at <strong>the</strong> edge<br />
Figure 5 Flat fitting scleral zone on <strong>the</strong><br />
same eye as seen in Figure 4. The<br />
fluorescein is only seen just beyond <strong>the</strong><br />
limbus, and <strong>the</strong>re is obvious blanching in<br />
<strong>the</strong> mid-periphery<br />
systems for both have been well documented<br />
in previous textbooks and summarised<br />
recently 19 , so it is not appropriate to expand<br />
fur<strong>the</strong>r on <strong>the</strong> preceding discussion which<br />
outlines <strong>the</strong>ir role.<br />
However, <strong>the</strong> fitting processes for RGP<br />
ScCLs have been more recently developed,<br />
hence <strong>the</strong> principles are outlined in <strong>the</strong> following<br />
text.<br />
Lens diameter<br />
The diameter is chosen according to <strong>the</strong><br />
appearance at <strong>the</strong> assessment and fitting<br />
process, and can be between 16mm and<br />
25mm. In fact, 18mm to 23mm is a more<br />
usual range for preformed lenses. Indeed,<br />
16mm is very small for a lens to be defined<br />
as a ScCL, that is, having a scleral bearing<br />
surface and essentially with corneal clearance.<br />
If <strong>the</strong> corneal diameter is taken to be<br />
12mm, and it is deemed desirable to allow<br />
an extra 1mm all round for limbal clearance,<br />
a 16mm total diameter only allows a 1mm<br />
scleral bearing annulus. The author<br />
acknowledges <strong>the</strong> valuable role for lenses<br />
with a diameter smaller than 16mm, but<br />
<strong>the</strong>y do not conform to this definition of a<br />
ScCL and are fitted according to a different<br />
rationale.<br />
A small variation in <strong>the</strong> diameter may not<br />
make much difference, but if a lens were to<br />
be made progressively smaller <strong>the</strong> original<br />
bearing surface would eventually be eliminated.<br />
The new bearing surface would <strong>the</strong>n<br />
be <strong>the</strong> sector of <strong>the</strong> sclera which was previously<br />
<strong>the</strong> transition zone with <strong>the</strong> larger<br />
diameter lens. The result is likely to be<br />
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Figure 6 The optic zone sagitta, and consequently, <strong>the</strong> apical clearance, is increased<br />
by steepening <strong>the</strong> BOZR<br />
Figure 7 The optic zone parameters<br />
can be defined according to <strong>the</strong> projection<br />
of <strong>the</strong> optic zone from <strong>the</strong> continuation of<br />
<strong>the</strong> scleral curve measured axially at <strong>the</strong><br />
apex and at <strong>the</strong> limbus<br />
increased settling back with reduction of<br />
<strong>the</strong> optic zone clearance.<br />
There are some comparative advantages<br />
and disadvantages of smaller and larger<br />
lenses. The author’s observation is that <strong>the</strong><br />
scleral topography just outside <strong>the</strong> limbus is<br />
more regular and symmetrical than <strong>the</strong><br />
more peripheral sclera. Smaller diameter<br />
ScCLs may be indicated when a tighter fitting<br />
is necessary. For example, <strong>the</strong>y should<br />
be tried when a non-ventilated 23mm diameter<br />
lens fails to seal well enough on <strong>the</strong><br />
sclera to prevent admission of an air bubble<br />
into <strong>the</strong> pre-corneal reservoir. Bearing on<br />
<strong>the</strong> most symmetrical region of <strong>the</strong> sclera<br />
leads to noticeably less decentration, which<br />
may reduce any prismatic effects.<br />
Smaller lenses can be made thinner than<br />
larger lenses because <strong>the</strong> rigidity is greater<br />
with smaller diameter lenses. The reduced<br />
mass, and less movement on <strong>the</strong> eye compared<br />
to larger lenses, may render a contact<br />
zone more tolerable. Hence <strong>the</strong>y can be fitted<br />
with less corneal clearance, which may<br />
prove to be advantageous if <strong>the</strong> vision is<br />
improved with a visual axis contact zone. A<br />
final advantage of <strong>the</strong> improved centration<br />
and closer proximity to <strong>the</strong> cornea is a more<br />
even depth of <strong>the</strong> pre-corneal fluid reservoir,<br />
this increases <strong>the</strong> possibility that a fenestration<br />
can be more successful than with larger<br />
diameter lenses. However, on <strong>the</strong> downside,<br />
<strong>the</strong> increased tightness of <strong>the</strong> fitting on <strong>the</strong><br />
eye and <strong>the</strong> reduced limbal clearance are significant<br />
drawbacks at times. Although such<br />
lenses are more likely to retain an air-free<br />
pre-corneal reservoir <strong>the</strong>y are more difficult<br />
to insert without a bubble in <strong>the</strong> first place,<br />
and because <strong>the</strong>y fit tighter on <strong>the</strong> eye, <strong>the</strong>y<br />
are distinctly more difficult to remove than<br />
larger diameter lenses.<br />
Optimal scleral zone alignment<br />
The bearing surface should be spread as<br />
evenly as possible over <strong>the</strong> sclera, but with<br />
optic zone clearance. In fact, 13.50mm to<br />
14.50mm is a usual back scleral radius (BSR)<br />
range for most preformed ScCLs. The bearing<br />
surface is displaced away from <strong>the</strong> limbus<br />
if <strong>the</strong> scleral zone is too steep, and may<br />
cause <strong>the</strong> lens to vault as it rests only at <strong>the</strong><br />
periphery, giving an appearance of excessive<br />
apical clearance. A flat fitting scleral zone<br />
shifts <strong>the</strong> bearing surface nearer to <strong>the</strong> limbus,<br />
but does not appreciably affect <strong>the</strong> apical<br />
clearance. Figure 3 diagrammatically<br />
illustrates scleral zone alignment and<br />
corneal clearance. Figures 4 and 5 are fluorescein<br />
photographs showing a steep and<br />
flat fitting scleral zone respectively.<br />
A glove fit on <strong>the</strong> sclera is not possible,<br />
nor essential, but <strong>the</strong> scleral zone needs to<br />
be sufficiently sealed to prevent <strong>the</strong> introduction<br />
of air bubbles into <strong>the</strong> pre-corneal<br />
fluid reservoir. An overall view of <strong>the</strong> scleral<br />
zone with a hand-held low magnification<br />
lamp is sufficient to see <strong>the</strong> extent of <strong>the</strong><br />
clearance beyond <strong>the</strong> limbus. Any areas of<br />
conjunctival blood vessel blanching, which<br />
are due to localised compression while <strong>the</strong><br />
lens is in situ, can be seen simultaneously<br />
with a white light source.<br />
Corneal and limbal clearance<br />
Achieving optimal clearance at <strong>the</strong> limbus<br />
and at <strong>the</strong> apex is determined by varying <strong>the</strong><br />
back optic zone radius (BOZR) and <strong>the</strong> back<br />
optic zone diameter (BOZD) in combination<br />
to give <strong>the</strong> optic zone sagitta (OZS). Varying<br />
<strong>the</strong> BOZR with a constant BOZD gives rise to<br />
a precisely calculable change to <strong>the</strong> central<br />
corneal clearance, as in Figure 6, but varying<br />
<strong>the</strong> BOZD with a constant BOZR does not<br />
because <strong>the</strong> curvature of <strong>the</strong> scleral bearing<br />
surface is an unknown quantity. This is <strong>the</strong><br />
same principle as traditional style PMMA<br />
ScCL fitting, but most modern fitting<br />
systems utilising <strong>the</strong> OZS principle calculate<br />
<strong>the</strong> combined specifications to give significant<br />
variations in apical and limbal<br />
clearance, <strong>the</strong>refore it is not necessary for<br />
<strong>the</strong> practitioner to try combinations of<br />
BOZRs and BOZDs.<br />
The corneal clearance can also be varied<br />
by changing <strong>the</strong> optic zone projection (OZP)<br />
in progressive increments but without reference<br />
to <strong>the</strong> BOZR or BOZD. Figure 7 illustrates<br />
OZP diagrammatically. The optic zone<br />
Figure 8 Off-axis apical contact zone in<br />
an advanced keratoconus wearing a nonventilated<br />
RGP scleral lens. This amount of<br />
contact was tolerated by <strong>the</strong> wearer and<br />
did not lead to any corneal erosion<br />
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Figure 9 The same eye as seen in<br />
Figure 8 with a significant increment in <strong>the</strong><br />
optic zone projection illustrating full<br />
corneal clearance.<br />
comparison to <strong>the</strong> corneal thickness, as<br />
shown in Figure 10. The fluorescence can<br />
be seen perfectly well with white light;<br />
cobalt blue filters reduce <strong>the</strong> brightness too<br />
much for <strong>the</strong> corneal thickness to be seen<br />
well.<br />
Apical clearance between 0.2mm and<br />
0.3mm is a satisfactory target for a nonventilated<br />
ScCL, approximately half a normal<br />
corneal thickness, with <strong>the</strong> pre-corneal<br />
fluid reservoir extending just beyond <strong>the</strong><br />
limbus. The exact measurement of corneal<br />
clearance is not critical, although if excessive<br />
it is more difficult to maintain an<br />
air-free pre-corneal fluid reservoir or for <strong>the</strong><br />
patient to insert <strong>the</strong> lens without an air<br />
methods consequent to <strong>the</strong> introduction of<br />
RGP materials. There are many fitting<br />
nuances which could not be covered, and<br />
<strong>the</strong>re are significant problem areas which<br />
have only briefly been touched upon.<br />
However, it is emphasised that <strong>the</strong> fitting<br />
processes have become straightforward and<br />
predictable in most cases, with a rapid<br />
arrival at <strong>the</strong> end-point mostly using nonventilated<br />
preformed RGP designs.<br />
ScCLs may be lens-of-choice when a<br />
result is needed more than at any o<strong>the</strong>r<br />
time. There are no conditions for which <strong>the</strong>y<br />
cannot be considered, so it is clearly necessary<br />
to preserve <strong>the</strong> clinical and manufacturing<br />
skills required . Since <strong>the</strong> introduction of<br />
is defined according to two axially measured<br />
parameters: <strong>the</strong> OZP from <strong>the</strong> extrapolation<br />
of <strong>the</strong> scleral curve measured at <strong>the</strong> apex<br />
and at <strong>the</strong> limbus. These increments are just<br />
clinically significant enough to keep <strong>the</strong><br />
number of lenses in <strong>the</strong> fitting system<br />
manageable. OZP is a function of <strong>the</strong> BSR,<br />
hence if <strong>the</strong> BSR is flattened, <strong>the</strong> OZP needs<br />
to be increased to compensate.<br />
The OZS or OZP for an initial trial lens is<br />
selected from an assessment of <strong>the</strong> overall<br />
corneal profile with <strong>the</strong> naked eye. If inaccurately<br />
estimated, <strong>the</strong>re is no major loss as<br />
<strong>the</strong> first lens inspected in situ gives a clear<br />
indication for subsequent lens selection.<br />
Keratometry and corneal topography are of<br />
limited value as nei<strong>the</strong>r provides any information<br />
about <strong>the</strong> peripheral cornea or <strong>the</strong><br />
projection from <strong>the</strong> sclera.<br />
The parameters are assessed simultaneously<br />
with <strong>the</strong> lens in situ, but <strong>the</strong> initial decision<br />
must be to determine <strong>the</strong> optimum<br />
scleral zone specifications as <strong>the</strong> scleral zone<br />
has an impact on <strong>the</strong> optic zone clearance.<br />
The lens is inserted filled with saline and fluorescein<br />
so that areas where <strong>the</strong> lens is clear<br />
of <strong>the</strong> surface can be easily distinguished<br />
from areas where <strong>the</strong> lens is in contact.<br />
Figures 8 and 9 demonstrate <strong>the</strong> effect of<br />
increasing <strong>the</strong> OZP to reduce corneal contact.<br />
Slit lamp biomicroscopy<br />
assessment of <strong>the</strong> optic zone<br />
If fluorescein is added to <strong>the</strong> saline prior to<br />
insertion, inspection of <strong>the</strong> optic zone using<br />
a cobalt blue filter shows any corneal<br />
contact zones. A slit lamp optical section<br />
can be used to measure <strong>the</strong> optic zone<br />
clearance. A pachometer is not necessary<br />
but <strong>the</strong> depth of <strong>the</strong> pre-corneal reservoir<br />
can be estimated with sufficient accuracy by<br />
Figure 10 Slit lamp optical cross section demonstrating <strong>the</strong> pre-corneal fluid reservoir.<br />
The lens, <strong>the</strong> reservoir and <strong>the</strong> cornea are all clearly seen in cross section. The depth of<br />
<strong>the</strong> reservoir is just less than <strong>the</strong> corneal thickness at <strong>the</strong> visual axis, <strong>the</strong>refore<br />
approximately 0.35mm to 0.4mm. By comparison, <strong>the</strong> cornea is 0.5mm to 0.6mm in<br />
thickness. The reservoir is thinner superiorly, and thicker inferiorly, indicating a degree of<br />
downward displacement of <strong>the</strong> lens. This is a normal feature with non-ventilated RGP<br />
ScCL fitting and does not usually have any detrimental effect (Courtesy of Scott Hau)<br />
bubble. If <strong>the</strong>re is insufficient clearance,<br />
corneal contact zones may reduce comfort<br />
and tolerance. Increasing <strong>the</strong> OZS or OZP by<br />
0.25mm alleviates a compressive central<br />
contact zone to give corneal clearance.<br />
Conclusion<br />
This is paper intended to provide an introduction<br />
to modern scleral contact lens practice,<br />
principally to outline changes in fitting<br />
RGP materials <strong>the</strong>ir application can be made<br />
at all grades of pathology where benefits<br />
can be seen. There remain some problems,<br />
and commitment to clinical practice is a<br />
prime requirement. The pathology may be<br />
active or progressive, so close liaison with<br />
ophthalmology is essential. A small number<br />
of practitioners are needed to maintain a<br />
functional service, but those who are not<br />
directly involved should also be aware of <strong>the</strong><br />
significant developments in recent years.<br />
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References<br />
1) Ezekiel D. Gas permeable haptic lenses.<br />
J Br Contact Lens Ass, (1983), 6(4),<br />
158 - 161.<br />
2) Bier N (1948). The practice of ventilated<br />
contact lenses. Optician 116, 497-501.<br />
3) Pullum KW, Hobley AJ and Parker JH.<br />
Dallos Award Lecture part two. Hypoxic<br />
corneal changes following sealed gas<br />
permeable impression scleral lens wear.<br />
J Br Contact Lens Assoc 1990; 13(1):<br />
83 - 87.<br />
4) Pullum KW, Hobley AJ and Davison C.<br />
100 + Dk: Does thickness make much<br />
difference? J Br Contact Lens Assoc<br />
1991; 6: 158 - 161.<br />
5) Pullum KW and Stapleton FJ (1997).<br />
Scleral lens induced corneal swelling:<br />
what is <strong>the</strong> effect of varying Dk and<br />
lens thickness? The CLAO Journal.<br />
23(4), 259 – 263.<br />
6) Pullum KW, Parker J H and Hobley AJ.<br />
Development of gas permeable<br />
impression scleral lenses. The Josef<br />
Dallos Award Lecture, part one. Trans<br />
BCLA Conf J. Br. Contact Lens Ass.<br />
1989; 77-81.<br />
7) Schein OD, Rosenthal P and Ducharme<br />
C. A gas-permeable scleral contact lens<br />
for visual rehabilitation. Am J<br />
Ophthalmol, (1990), 109, 318 - 322.<br />
8) Kok JHC, and Visser R. Treatment of<br />
ocular surface disorders and dry eyes<br />
with high gas-permeable scleral lenses.<br />
Cornea, (1992), 11, 518 - 522.<br />
9) Tan DTH, Pullum KW and Buckley RJ.<br />
Medical Applications of Scleral Contact<br />
Lenses: 2. Gas-Permeable Scleral<br />
Contact Lenses. Cornea, (1995), 14(2),<br />
130 – 137.<br />
10) Pullum KW and Buckley RJ. A study of<br />
530 patients referred for rigid gas<br />
permeable scleral contact lens<br />
assessment. Cornea, (1997), 16(6),<br />
612 – 622.<br />
11) Cotter J and Rosenthal P. Scleral contact<br />
lenses. J Am Optom Ass, (1998), 69,<br />
33 - 40.<br />
12) Swann PG and Mountford J. Facial<br />
nerve palsy and scleral contact lenses.<br />
Br J Optom and dispensing, (1999), 7,<br />
85-87.<br />
13) Ramero-Rangel T, Stavrou P, Cotter JM,<br />
Rosenthal P, Baltatzis S, Foster CS.<br />
Gas-permeable scleral contact lens<br />
<strong>the</strong>rapy in ocular surface disease. Am J<br />
Ophthalmology, (2000), 130, 25 - 32.<br />
14) Rosenthal P, Cotter JM, Baum J.<br />
Treatment of persistent corneal<br />
epi<strong>the</strong>lial defect with extended wear of<br />
a fluid-ventilated gas-permeable scleral<br />
contact lens. Am J Ophthalmology,<br />
(2000), 130, 33 - 41.<br />
15) Tappin MJ, Pullum KW, and Buckley RJ.<br />
Scleral contact lenses for overnight<br />
wear in <strong>the</strong> management of ocular sur<br />
face disorders. Eye, (2001). 15,<br />
168-172.<br />
16) Rosenthal P, Cotter J. The Boston<br />
scleral lens in <strong>the</strong> management of<br />
severe ocular surface disease.<br />
Ophthalmol Clin North Am<br />
(2003);16:89-93<br />
17) Fine P, Savrinski G, Millodot M. Contact<br />
lens management of a case of Stevens-<br />
Johnson syndrome: a case report.<br />
Optometry (2003) Oct; 74:659-64<br />
18) Looi AL, Lim L, Tan DT. Visual rehabili<br />
tation with new-age rigid gas-perme<br />
able scleral contact lenses - a case<br />
series. Ann Acad Med Singapore<br />
(2002);31:234-7<br />
19) Contact Lenses, edited by Anthony<br />
J Phillips and Lynne Speedwell,<br />
Publishers Elsevier, Chapter 15, Scleral<br />
Contact Lenses, by KW Pullum,<br />
pp 333 - 353.<br />
Acknowledgements<br />
The author is grateful for <strong>the</strong> assistance of<br />
<strong>the</strong> cornea consultants at Moorfields and<br />
Oxford Eye Hospitals, and for <strong>the</strong>ir support<br />
over many years in a long-term project<br />
modernising scleral lens practice and developing<br />
new clinical and manufacturing techniques.<br />
Figure 10 is courtesy of Scott Hau,<br />
senior optometrist, Moorfields Eye Hospital.<br />
For fur<strong>the</strong>r information<br />
contact address:<br />
Ken Pullum, 73 Railway Street, Hertford,<br />
Hertfordshire, United Kingdom, SG14 1RP,<br />
(kenpullum@btinternet.com,<br />
kenpullum@tiscali.co.uk)<br />
Continuing<br />
education and<br />
training initiative<br />
For all CET<br />
Queries please<br />
contact:<br />
Jessica<br />
Buckingham<br />
CET,<br />
McMillan-Scott,<br />
9 Savoy Street<br />
London,<br />
WC2E 7HR<br />
Telephone:<br />
0207 878 2412<br />
Fax:<br />
0207 379 7118<br />
E-mail:<br />
jessica@mcms<br />
london.co.uk<br />
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Module questions<br />
Course code: c-4090<br />
Please note, <strong>the</strong>re is only one correct answer. Enter online or by form provided.<br />
1. For a highly irregular corneal topography would you<br />
try as first choice...<br />
a. Non-ventilated impression RGP scleral lens?<br />
b. Preformed fenestrated RGP scleral lens?<br />
c. Fenestrated impression PMMA scleral lens?<br />
d. Non-ventilated preformed RGP scleral lens?<br />
2. What is <strong>the</strong> optimum corneal clearance for a<br />
non-ventilated RGP scleral lens?<br />
a. Not more than 0.1mm<br />
b. Not less than 1.0mm<br />
c. Between 0.2mm and 0.3mm<br />
d. Between 0.4mm and 0.9mm<br />
3. If <strong>the</strong> BSR is changed from 13.50mm to 14.50mm<br />
without altering <strong>the</strong> OZP, would you expect...<br />
a. Increased apical clearance<br />
b. Reduced apical clearance<br />
c. There would be no difference<br />
d. There would be increased vaulting from <strong>the</strong> scleral zone<br />
4. What is <strong>the</strong> most probable objective when<br />
fenestrating an RGP scleral lens?<br />
a. To enable easier handling<br />
b. To increase apical clearance<br />
c. To create corneal contact<br />
d. To give a crescent-shaped bubble under <strong>the</strong> lens<br />
5. What is <strong>the</strong> usual objective when fenestrating a<br />
PMMA scleral lens?<br />
a. To give a crescent shaped bubble<br />
b. To increase apical clearance<br />
c. To facilitate oxygenated tear exchange<br />
d. To create corneal contact<br />
6. What would be <strong>the</strong> reason for considering a scleral<br />
lens in moderate keratoconus?<br />
a. To improve on vision achieved with a corneal lens<br />
b. To give increased oxygenation<br />
c. To alleviate corneal contact<br />
d. To create corneal contact<br />
7. Comparing small and large diameter non-ventilated<br />
scleral lenses, would you expect...<br />
a. More limbal clearance with <strong>the</strong> smaller lens?<br />
b. More apical clearance with <strong>the</strong> smaller lens?<br />
c. Better tear pool retention with <strong>the</strong> larger lens?<br />
d. The smaller lens to be more stable on <strong>the</strong> eye?<br />
8. What is <strong>the</strong> most common modern indication for<br />
scleral lenses?<br />
a. Aphakia<br />
b. High myopia<br />
c. Keratoconus<br />
d. Corneal transplant fitted post-operatively<br />
9. What is meant by <strong>the</strong> term sealed in <strong>the</strong> context of<br />
scleral lens practice?<br />
a. Near perfect alignment to <strong>the</strong> cornea<br />
b. Near perfect alignment to <strong>the</strong> sclera<br />
c. A lens retaining an air bubble-free tear pool<br />
d. A lens which is very difficult to remove<br />
10. Under what circumstances could a PMMA scleral be<br />
arguably preferable to an RGP scleral?<br />
a. For keratoconus<br />
b. Never<br />
c. For aphakia<br />
d. For work in dusty environments<br />
11. If <strong>the</strong> BSR is changed from 14.50mm to 13.50mm, & <strong>the</strong> OZP<br />
is increased one clinically significant step, would you expect...<br />
a. An 0.25mm increase in <strong>the</strong> apical clearance?<br />
b. A 0.50mm or greater increase in <strong>the</strong> apical clearance?<br />
c. No change in <strong>the</strong> apical clearance?<br />
d. A reduction in apical clearance of 0.25mm?<br />
12. What would be <strong>the</strong> probable outcome of reducing <strong>the</strong> diameter<br />
of a non-ventilated RGP scleral lens from 23mm to 18mm?<br />
a. Increased apical clearance<br />
b. More decentration of <strong>the</strong> lens<br />
c. An apical contact zone<br />
d. More chance of <strong>the</strong> lens falling out<br />
An answer return form is included in this issue.<br />
It should be completed and returned to:<br />
CET initiatives (c-4090), OT, McMillan Scott, 9 Savoy Street, London, WC2E 7HR by November 15. Under no circumstances will forms received after this date be<br />
marked – <strong>the</strong> answers to <strong>the</strong> module will be published in our December 15 issue.<br />
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