Air Quality Guidelines - World Health Organization Regional Office ...

72 chapter 5
Table 10. Some concentration–response relationships in occupational
exposure to carbon disulfide
Carbon disulfide Duration of Symptoms and signs Reference
concentration exposure
(mg/m 3 ) (years)
500–2500 0.5 Polyneuritis, myopathy, 1
acute psychosis
450–1000 < 0.5 Polyneuritis, encephalopathy 2
200–500 1–9 Increased ophthalmic 3
pressure
60–175 5 Eye burning, abnormal 4
pupillary light reactions
31–137 10 Psychomotor and 5
psychological disturbances
29–118 15 Polyneuropathy, abnormal 6, 7
EEG, conduction velocity
slowed, psychological
changes
29–118 10 Increase in coronary 8–11
mortality, angina pectoris,
slightly higher systolic and
diastolic blood pressure
40–80 2 Asthenospermia, 12
hypospermia, teratospermia
22–44 > 10 Arteriosclerotic changes 13
and hypertension
30–50 > 10 Decreased immunological 14
reactions
30 3 Increase in spontaneous 15
abortions and premature
births
20–25 < 5 Functional disturbances of 16, 17
the central nervous system
10 10–15 Sensory polyneuritis, 18
increased pain threshold
10 10–15 Depressed blood 19
progesterone, increased
estriol, irregular
menstruation