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Pediatric Terrorism and Disaster Preparedness: A ... - PHE Home

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espect to incident waves <strong>and</strong> the degree of reflected shock waves to which the victim is<br />

exposed.<br />

Primary blast injury. Primary blast injuries (PBI) are injuries caused specifically by<br />

exposure of the body to the blast wave. Pulmonary barotrauma, air embolization, <strong>and</strong><br />

intestinal perforation are the unique principal causes of death after a blast. Although most<br />

injuries in an explosion are secondary, tertiary, <strong>and</strong> miscellaneous (crush, burn,<br />

inhalational), a person close enough to a detonation would be subjected to the effects of<br />

the blast on a microscopic level.<br />

Urban bomb blasts tend to have the following characteristics:<br />

• Most victims sustain minor injuries.<br />

• Most injuries affect the head, neck, <strong>and</strong> extremities.<br />

• Torso injuries are uncommon yet lethal.<br />

• Primary blast injuries are uncommon because victims tend to die before arriving<br />

at the hospital.<br />

However, because all bomb blast incidents are different, the types of injuries seen are<br />

variable. A blast that occurs in an enclosed space, such as a bus, is associated with more<br />

severe injuries <strong>and</strong> a higher incidence of primary blast injuries. The number of casualties<br />

would be expected to be less than in an equipotent detonation in open space. Mortality is<br />

also higher when a blast occurs in an enclosed space, because the shock wave is<br />

contained <strong>and</strong> reaches a higher overpressure <strong>and</strong> a longer positive phase. However,<br />

containment of the wave does not affect the generation of propelled debris. Therefore,<br />

secondary <strong>and</strong> tertiary injuries, including amputations from large objects, are the same<br />

whether the blast occurs in an enclosed space or open air.<br />

The spectrum of PBI reflects involvement of the gas-containing organs <strong>and</strong> the<br />

pathophysiologic effects of these organs on other systems (Table 7.2). As in conventional<br />

trauma, all victims should be managed with careful attention to the airway, breathing, <strong>and</strong><br />

circulation; however, in certain patients, complications may arise with respect to positivepressure<br />

ventilation <strong>and</strong> fluid resuscitation management.<br />

Blast lung injury <strong>and</strong> air embolization. The anatomic structure of the lung makes it<br />

susceptible to the effects of blast barotrauma. Alveolar spaces are engulfed by delicate<br />

capillaries in a way that maximizes the surface area available for gas exchange.<br />

Pathophysiology. The pathophysiology induced by the blast involves the spalling of<br />

particles across the tissue-gas interface (alveolus) with the generation of micro-tears. This<br />

fills the air space with blood, edema, <strong>and</strong> tissue particles, impairing gas exchange. The<br />

most common lesion of the airway is the stripped-epithelium lesion, in which the<br />

bronchial epithelium <strong>and</strong> mucociliary apparatus are stripped from the basal lamina,<br />

resulting in ulcerations of the submucosa <strong>and</strong> impaired clearing of secretions. Structural<br />

tears occur through interfaces of blood vessels <strong>and</strong> air spaces, creating direct openings<br />

where air bubbles could escape into the circulation.<br />

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