4. Clinical Guidelines for Liver Transplantation (PDF) - British ...
4. Clinical Guidelines for Liver Transplantation (PDF) - British ...
4. Clinical Guidelines for Liver Transplantation (PDF) - British ...
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Guidebook <strong>for</strong> the Solid Organ Transplant Programme Chapter 4<br />
Appendix J<br />
TREATMENT FOR OTHER OPPORTUNISTIC INFECTIONS IN<br />
LIVER TRANSPLANT RECIPIENTS<br />
Organism Site of Infection Drug of Choice<br />
Herpes Simplex Virus (HSV)<br />
Mucocutaneous<br />
to mild<br />
Acyclovir 800 mg PO qid <strong>for</strong> 7 days<br />
OR<br />
Valacyclovir 1000 mg PO tid <strong>for</strong> 7 to 10 days<br />
Varicella-Zoster Virus (VZV)<br />
Pneumocytis Carinii Pneumonia<br />
to severe<br />
Respiratory<br />
Encephalitis<br />
Mild<br />
Severe<br />
Prophylaxis<br />
Treatment<br />
Acyclovir 5 mg/kg IV q 8h <strong>for</strong> 7 days<br />
Acyclovir 10 mg/kg IV q 8h <strong>for</strong> 10 days<br />
Acyclovir 10 mg/kg IV q 8h <strong>for</strong> 10 days<br />
Acyclovir 800 mg PO <strong>for</strong> 4 to 5x daily <strong>for</strong> 7 to 10<br />
days OR<br />
Valacyclovir 1g to tid x 7 to 10 days<br />
Acyclovir 10 to 12 mg/kg IV q 8h <strong>for</strong> 7 to 14 days<br />
None<br />
TMP-SMX 5 mg/kg IV (based on TMP<br />
component) q 6h <strong>for</strong> 21 days<br />
Sulfa allergy: Pentamidine IV 4mg/kg/daily <strong>for</strong> 21<br />
days<br />
Chapter 4 – <strong>Clinical</strong> <strong>Guidelines</strong> <strong>for</strong> <strong>Liver</strong> <strong>Transplantation</strong> – July, 2010 Page 54<br />
See Page 1 <strong>for</strong> disclaimer
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