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Tramadol hydrochloride 50mg/ml <strong>inj</strong><br />

Trade name<br />

Trabilin<br />

Drug class<br />

Opioid analgesics<br />

Presentation<br />

Clear colorless solution, in 2mL white glass ampoule with a blue breaking point<br />

Prescriber<br />

All clinicians<br />

Cost<br />

RM2.50 per amp. FOC for inpatient use<br />

Indication<br />

Moderate to severe acute pain<br />

Dose<br />

Adults: SC/IM/IV 30 – <strong>100mg</strong> 6 hourly.<br />

Post operative pain: <strong>100mg</strong> initial dose, then 50mg every 10-20 minutes if<br />

necessary during first hour to total max. 250mg (including initial dose) in first<br />

hour, then 50 – <strong>100mg</strong> every 4-6 hours; max: 600mg daily.<br />

Children >1 yr: 1 – 2mg/kg body weight.<br />

Renal failure: 200mg (daily dose). Liver impairment: 50mg every 12 hours<br />

Geriatric above 75 yr: Recommended daily dose should not exceed 300mg daily.<br />

Location<br />

In-patient<br />

Administration IM <strong>inj</strong>ection: Yes<br />

SC <strong>inj</strong>ection: Yes<br />

IV <strong>inj</strong>ection: Suitable over 2 to 3 minutes<br />

IV infusion: Yes after dilution<br />

Stability / expiry Reconstituted solution: NA<br />

Compatibility Compatible fluids: Glucose 5%, NS, Ringer’s solution<br />

Compatible drugs: NA<br />

Compatible via Y site: NA<br />

Compatible in syringe: NA<br />

Incompatibility Incompatible fluids: NA<br />

Incompatible drugs: Diazepam, glyceryl trinitrate, midazolam<br />

Special precautions • IV bolus administered slowly over 3–4 min to reduce incidence of<br />

nausea/vomiting, sweating and occasionally hypertension.<br />

• Convulsions reported, usually after rapid intravenous <strong>inj</strong>ection.<br />

• In case of poor analgesic effect, it is possible to administer another single<br />

dose after 30–60 minutes of the previous dose.<br />

Special notes • Ward stock in some wards. Check PIS for updated list of wards.<br />

• Controlled drug. Record of use must be maintained in the wards.<br />

• Symptoms of overdosage include miosis, vomiting, cardiovascular collapse,<br />

sedation and coma, seizures and respiratory depression. Naloxone can be used


Patient Information<br />

Prepared/checked by<br />

Date compiled/edition<br />

to reverse respiratory depression. Fits can be controlled with diazepam.<br />

Patient may experience side effects such as nausea, vomiting headache, dizziness,<br />

restlessness or drowsiness<br />

Azwa Bt Haris / PDS / HKD / PL<br />

9 June 2008, 1 st edition

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