immunoglobulin G 2.5g 5g inj (IVI)

Human Normal Immunoglobulin (IVIG)
Trade name
Vigam® Liquid
Drug class
Immunoglobulin
Presentation
Intravenous sterile colourless liquid containing 2.5g / vial
Cost
RM320.00 per vial
Approved indications: Govt servants FOC, others – include total cost in hospital
bill if patient is unable to pay.
Prescriber
Consultants & Lecturers
Indication
ITP, Kawasaki disease and paediatric BMT (part of package)
Dose
400mg/kg/day x 5 days or 2g/day x 1 dose
Location
In patient pharmacy
Administration IM injection: NA
SC injection: NA
IV injection: NA
IV infusion: Initial rate, 0.01 – 0.02mL/kg/min for 30min, then gradually increase
to 0.04mL/kg/min up to max rate of 3mL/min
Intrathecal: NA
Intraperitoneal: NA
Stability / expiry Reconstituted solution – Contains no antimicrobial preservatives, use promptly
after reconstitution
Undiluted solution: - Store at 2-8ºC and protect from light. A short period of up
to 3 months at 25ºC is possible within the storage date printed on the label
Compatibility Compatible fluids: NaCl 0.9%, D5%
Compatible drugs: NA
Compatible via Y site: Fluconazole – avoid mixing with other drugs
Compatible in syringe: NA
Incompatibility Incompatible fluids: NA
Incompatible drugs: NA
Special precautions • Adequate hydration is required prior to the infusion of IVIG
• Follow recommended infusion rate to minimize adverse reactions
• During the infusion, urine output and serum creatinine levels should be
monitored
• Avoid concomitant use of loop diuretics
• Single use only. Any left over should be discarded
Special notes • Approved indications: All requests for IVIG must be accompanied by

Borang Ubat Khas. Completed form does not need to be sent for Director’s
approval. File to be kept in IP. Govt servants FOC, others to pay.
Other indications:
• Govt servants: to pay in full. Those unable to pay cost will need to get the
Borang Ubat Khas form completed and Director’s approval for supply.
• Others: To pay in full. Patients who are unable to pay in full need to fill the
Borang Ubat Khas form and be assessed by the social worker. Completed
forms will be sent for Director’s approval. Patient will be billed for amount
assessed. Copy of approved form must be sent to PTj Kewangan (Hasil)
Patient Information • Adverse reactions include chills, headache, GI side effects, rash and low BP
Prepared/checked by
Date
compiled/edition
• Inform doctor if patient feels unwell during infusion
Tan Wen Chieh / PDS / HKD / PL
23/02/07 / 1 st edition