Sarawak Biodiversity Centre - NRE
Sarawak Biodiversity Centre - NRE
Sarawak Biodiversity Centre - NRE
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SILVESTROL: RESEARCH IN PROGRESS AT PRE-<br />
CLINICALS TOWARDS HUMAN CLINICAL TRIALS<br />
In vitro<br />
<br />
<br />
Various types of cancer cell<br />
line<br />
Unique mechanism of action<br />
in cancers<br />
Evaluation<br />
Animal cancer models<br />
In vitro human leukemia<br />
blood cells<br />
<br />
<br />
Cell type selectivity<br />
Overcome drug resistance in<br />
cancers<br />
Issues<br />
Supply<br />
Difficult to synthesize<br />
Toxicity<br />
Efficacy in humans<br />
others
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