Lithium: The Forgotten Wonderdrug
Lithium: The Forgotten Wonderdrug
Lithium: The Forgotten Wonderdrug
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Disadvantages of <strong>Lithium</strong><br />
• Narrow window between therapeutic and toxic blood levels<br />
– Requires careful monitoring of blood levels<br />
• Thyroid reactions<br />
– Hypothyroidism<br />
– Hyperthyroidism<br />
• Renal reactions<br />
– Polyuria<br />
– Interstitial fibrosis<br />
– Possibility of reduced filtration rate<br />
• Cardiovascular reactions<br />
– Heart block<br />
– Reversible T wave changes on EKG<br />
• Weight gain
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