Lithium: The Forgotten Wonderdrug
Lithium: The Forgotten Wonderdrug
Lithium: The Forgotten Wonderdrug
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Risk Reduction in Diagnostic<br />
Subtypes<br />
• Bipolar disorder, all suicidal acts<br />
– From 6.1% per year without lithium to 0.295% per<br />
year with lithium<br />
• 20.7-fold or 95.2% reduction of risk<br />
• Mixed groups of recurrent depressive and<br />
schizoaffective disorders, all suicidal acts<br />
– From 2.12% per year without lithium to 0.193% per<br />
year with lithium<br />
• 11.0-fold or 90.9% reduction of risk<br />
Baldessarini RJ, Tondo L, Hennen J. <strong>Lithium</strong> treatment and suicide risk in major<br />
affective disorders: update and new findings. J Clin Psychiatry. 2003;64 Suppl 5:44-52.