Lithium: The Forgotten Wonderdrug
Lithium: The Forgotten Wonderdrug
Lithium: The Forgotten Wonderdrug
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Acute Manic or Mixed Episodes<br />
• Mild/Moderate<br />
– First line, lithium monotherapy or valproate or<br />
antipsychotic like olanzapine<br />
• Severe<br />
– First line is initiation of lithium plus an antipsychotic or<br />
valproate and an antipsychotic<br />
• If the episode is breakthrough while patient is<br />
already on lithium maintenance<br />
– Optimize dose<br />
– Add valproate to the lithium