Lithium: The Forgotten Wonderdrug
Lithium: The Forgotten Wonderdrug
Lithium: The Forgotten Wonderdrug
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Rapid Cycling<br />
• Four or more mood episodes within single year<br />
demarcated by partial or full remission or switch<br />
to episode of opposite polarity<br />
• Look for causes<br />
– Comorbid substance use<br />
– Thyroid dysfunction<br />
– Antidepressant can contribute<br />
• Initial treatment should be lithium, valproate,<br />
lamotrigine or a combination