Lithium: The Forgotten Wonderdrug
Lithium: The Forgotten Wonderdrug
Lithium: The Forgotten Wonderdrug
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Episode Recurrence in Bipolar I<br />
Disorder – Before <strong>Lithium</strong><br />
• Mania<br />
– 1.1 recurrences per year<br />
– 24.7% of time ill<br />
• Depression<br />
– 0.54 recurrences per year<br />
– 19.2% of time ill<br />
Tondo L, Baldessarini RJ, Hennen J, Floris G. <strong>Lithium</strong> maintenance treatment of depression and<br />
mania in bipolar I and bipolar II disorders. Am J Psychiatry. 1998 May;155(5):638-45.