Lithium: The Forgotten Wonderdrug
Lithium: The Forgotten Wonderdrug
Lithium: The Forgotten Wonderdrug
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Potential Toxicity of Long Term<br />
<strong>Lithium</strong> Use<br />
• Thyroid function was investigated in 100 manicdepressive<br />
patients<br />
– Goiter was more common in patients treated with<br />
lithium for 1-5 years (44%) and more than 10 years<br />
(50%) than in patients who never received lithium<br />
(16%)<br />
– Hypothyroidism was found in 21% of patients treated<br />
with lithium for more than 10 years<br />
Perrild H, Hegedus L, Baastrup PC, Kayser L, Kastberg S. Thyroid function and<br />
ultrasonically determined thyroid size in patients receiving long-term lithium<br />
treatment. Am J Psychiatry. 1990 Nov;147(11):1518-21.
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