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i<br />

v<br />

Organization<br />

Director’s Report<br />

Research Highlights<br />

2 Good Housekeep<strong>in</strong>g<br />

3 Poor Transport Cuts to the Bone<br />

4 Cell Fusion may Create Niche for Immune Cell Education<br />

5 Interferon Production Mechanisms Revealed<br />

6 Halt<strong>in</strong>g the Inflammation Overload<br />

7 How Eat<strong>in</strong>g Cell ‘Corpses’ Reduces Inflammation<br />

8 Signal<strong>in</strong>g Simplified<br />

9 Identification of a Novel Intracellular Second Messenger<br />

10 Look<strong>in</strong>g Beneath the Surface<br />

11 Regulat<strong>in</strong>g Antibody Production<br />

12 Immune Cells Stimulated by Calcium Levels<br />

13 Silenc<strong>in</strong>g Allergic Inflammation<br />

14 How Cells Switch From Killers to Helpers<br />

15 Dampen<strong>in</strong>g Dangerous Inflammation<br />

16 On the Road to a Vacc<strong>in</strong>e Aga<strong>in</strong>st Tumors<br />

17 Understand<strong>in</strong>g Cancer <strong>in</strong> Mice and Men<br />

18 Award W<strong>in</strong>ners 2007<br />

19 Outstand<strong>in</strong>g Contribution of the Year<br />

20 2007 Excellent Paper Award and Excellent Poster of the Year<br />

Research Activities<br />

24 Laboratory for Developmental Genetics<br />

26 Research Unit for Lymphocyte Clon<strong>in</strong>g<br />

28 Laboratory for Lymphocyte Development<br />

30 Laboratory for Transcriptional Regulation<br />

32 Laboratory for Cell Signal<strong>in</strong>g<br />

34 Research Unit for S<strong>in</strong>gle Molecule Imag<strong>in</strong>g<br />

36 Laboratory for Lymphocyte Differentiation<br />

38 Research Unit for Molecular Systems Immunology<br />

40 Laboratory for Epithelial Immunobiology<br />

42 Laboratory for Mucosal Immunity<br />

44 Laboratory for Immunological Memory<br />

46 Laboratory for Immune Diversity<br />

48 Laboratory for Host Defense<br />

50 Laboratory for Infectious Immunity<br />

52 Laboratory for Dendritic Cell Immunobiology<br />

54 Laboratory for Innate Cellular Immunity<br />

56 Research Unit for Therapeutic Model<br />

58 Laboratory for Autoimmune Regulation<br />

iii

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