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ISNVD Abstract Book

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volume and higher pressure. There are proponents for both approaches. While hand injection mimics<br />

physiological venous flow, pressure injectors are more accurate, reproducible, make some flow related<br />

analyses quantifiable. Either or both approaches may be utilized in any case depending on the<br />

objectives desired. There are some modern injectors that allow low-pressure administration of contrast<br />

and perhaps such an equipment should be preferentially used.<br />

3. Interpretation of venographic pictures. Left versus right IJV<br />

It may seem obvious that venography of both internal jugular veins should be interpreted in the same<br />

way. But there are some arguments favoring a different approach to the right vs. left (or: dominant vs.<br />

non-dominant) jugular vein. Right internal jugular vein is usually bigger, its valve has longer leaflets;<br />

left internal jugular vein is smaller and has more transversally oriented valve leaflets. Perhaps these<br />

parameters should be taken into account while deciding if the vein assessed should be interpreted as<br />

normal, or pathological and requiring endovascular treatment. These dilemmas will be of special<br />

importance if the definition of pathology were based on quantitative assessment of the flow (which in<br />

most normal individuals is asymmetric). It is important to emphasize that asymmetry between the<br />

jugular veins itself is not pathological, however other attributes such as stenoses, need to be<br />

considered in the context of each individual jugular vein. In terms of what is a stenosis, there is little<br />

consensus, the authors of already published research have utilized an arbitrary definition of 50%<br />

luminal restriction when compared to nominal diameter of the proximal vein. However, the jugular<br />

vein stenosis in particular is more difficult to assess because of the routine dilatation of the vein<br />

cranially to the valve. Therefore, perhaps a nominal diameter of the vein proximal to the bulb or most<br />

dilated part of the distal jugular should be utilized.<br />

A few other considerations that are relevant in regards the jugular veins are, that unless the<br />

diagnostic catheter is placed at the level of the skull base/jugular foramen, one is likely to miss a<br />

multitude of anatomical and flow related anomalies in the upper jugular vein. Additionally, if an<br />

angled catheter is used and it is pointed medially, the injected contrast will specifically opacify<br />

through the mastoid and condylar emissary veins the vertebral and cervical epidural plexuses<br />

suggesting an underlying hemodynamic anomaly when none exists. Therefore, it is important that the<br />

angled catheters are directly laterally at the level of the jugular foramen. Frequently, the transverse<br />

process of the C1 vertebra will visibly indent the jugular vein (since the vein lies on this bony<br />

structure) however, a balloon will inflate under minimal pressure and Valsalva maneuver will enlarge<br />

the compressed vein during angiography or IVUS confirming this normal relationship.<br />

4. Interpretation of venographic pictures. Jugular valve.<br />

What should be regarded as a pathologic valve? Currently there are two ways of thinking. Firstly,<br />

some interpret jugular valve as abnormal if a narrowing at its level is detected: using venography,<br />

through inflating a compliant angioplastic balloon, or through intravascular ultrasound (IVUS).<br />

Secondly, some suggest that the valve should be interpreted as abnormal only if flow disturbances are<br />

found (no outflow through the vein, venous outflow slowed down, reversed flow direction, outflow<br />

through collaterals, etc). Probably more research in healthy individuals is needed to solve this<br />

problem. Such a research, however, will not be easy to perform taking into account an invasive nature<br />

of venography.<br />

5. Interpretation of venographic pictures. Azygous vein<br />

There is widespread discrepancy between performance and interpretation of azygous venograms.<br />

Firstly, there are no standards as to where exactly along the course of the azygous vein should a<br />

contrast injection be made, any injection made in the arch is likely to miss pathology in more proximal<br />

portions, while abdominal injections in a much smaller caliber vessel may artificially induce reverse

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