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IMPROVEMENT OF CHRONIC FATIGUE AFTER ENDOVASCULAR TREATMENT FOR CHRONIC CEREBROSPINAL VENOUS INSUFFICIENCY IN THE PATIENTS WITH MULTIPLE SCLEROSIS Marian Simka, Piotr Janas, Tomasz Ludyga, Paweł Latacz, Marek Kazibudzki Affiliation: Euromedic Specialist Clinics, Department of Vascular & Endovascular Surgery, Katowice, Poland Purpose. The aim of this study was to evaluate impact of endovascular treatment for chronic cerebrospinal venous insufficiency on chronic fatigue in multiple sclerosis patients. Methods. Severity of fatigue was assessed in 340 multiple sclerosis patients after the follow-up of 6 months. For this evaluation the Fatigue Severity Scale (FSS) was used. Results. We found statistically significant improvement of fatigue. Six months after the treatment mean FSS score dropped from 4.7 to 3.8. However, these post-procedural changes were not evenly distributed. While the patients with no fatigue (FSS
Characteristics of patients who maintained improvement at Six Months • Number of patients - 50 • Duration of MS - 5.1 • M:F- 28:22 • Type of MS - RR:SP:PP=19:18:13 • Mean age - 45 (33 -60) – Some comments • increased Physical activity and mobility, feeling energetic and no longer taking afternoon nap • Now cycling/swimming • Feel strange, increased co -ordination skills Characteristics of Patients Who Relapsed After Initial Improvement • Number of patients -14 • Duration of MS -11 years • M:F=7:7 • Mean age -49yrs • Type of MS-RR:SP:PP -3:5:6 Characteristics of Patients With No Change After Treatment • Number of patients - 6 • Duration of MS -10 years • M:F-1:5 • Mean age -47.5 • Type of MS-RR:SP-3:3 MSFC SCORE • MSFC SCORE= {Z arm average + Z leg average + Z cognitive}/3.0 • Pre-treatment score 0.040397263 ± 0.56 • Post treatment score 0.058432175 ± 0.74 • p=0.11 • A decrease or an increase in the MSFC score represents, respectively, deterioration or improvement in neurological functions. MSQoL QoL(Physical ), p
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PRINCIPLE CONSIDERATIONS ON VENOUS
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using several methods. These method
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